Background: Knee osteoarthritis (KOA) is a common degenerative and progressive joint disorder that negatively influences patients’ quality of life. Intra-articular therapies, such as hyaluronic acid (HA) and platelet-rich plasma (PRP), have garnered attention for their potential to manage osteoarthritis OA symptoms effectively. This systematic review aims to identify the effectiveness and safety of HA and PRP treatment modalities in treating KOA. Methods: A literature search was conducted across MEDLINE (PubMed), Web of Science Core Collection, and Science Direct Collection Elsevier. Twenty-three randomized controlled trials, cohort studies, and observational studies were included in the review. The selection criteria focused on studies published in English within the last 10 years, involving subjects with KOA treated with intra-articular injections of HA or PRP and reporting on pain, function, or overall treatment efficacy outcomes. Results: The analysis showed that both HA and PRP significantly improve functionality and reduce pain in KOA patients. High molecular weight HA consistently reduced pain and improved joint mobility in various studies. PRP had better long-term outcomes when combined with HA, leading to greater pain reduction and functional improvement. Both therapies had generally favorable safety profiles, with only minor adverse events reported. However, there were potential biases identified across the studies, such as selection, performance, detection, and reporting biases, which impacted the reliability of the results. Conclusions: Intra-articular treatments with HA and PRP show promise in managing knee osteoarthritis, with personalized treatment plans and further research needed to confirm these findings.

Introduction: The sequelae after a stroke cause proprioceptive disorders that cause disabilities in the individual, negatively influencing the performance of daily activities. Objectives: This paper aims to analyze the effectiveness of virtual reality (VR) rehabilitation methods through various technologies in post-stroke patients. Material and method: Web of Science Core Collection database was interrogated. Clinical trials from the last five years were included in the review. Results: Twelve papers were included in the literature review. Immersive and non-immersive technologies were used as an adjunct or standalone therapy in post-stroke rehabilitation, with 30 to 40 minutes daily sessions or 3 to 4 times a week. Virtual reality therapy was performed. The length and the therapy were heterogenous, with patients receiving conventional physiotherapy exercises, mirror therapy or robotic therapy. Conclusions: VR therapy seems to improve patients functioning and positively influences the rehabilitation of the upper extremities in post-stroke patients, especially in association with conventional physiotherapy. Rezumat Introducere: Sechelele după un accident vascular cerebral (AVC) provoacă tulburări proprio¬ceptive care determină dizabilități la individ, influențând negativ desfășurarea activităților zilnice. Obiective: Această lucrare își propune să analizeze eficacitatea metodelor de reabilitare în realitate virtuală (VR) prin diverse și tehnologii la pacienții post-AVC. Material și metodă: A fost interogată baza de date Web of Science Core Collection. Studiile clinice din ultimii 5 ani au fost incluse în revizuire. Rezultate: Doisprezece lucrări au fost incluse în analiza literaturii de specialitate. Tehnologiile imersive și non-imersive au fost utilizate ca terapie adjuvantă sau de sine stătătoare în reabilitarea post-accident vascular cerebral, cu ședințe zilnice de 30 până la 40 de minute sau de 3 până la 4 ori pe săptămână, au fost efectuate terapii cu realitate virtuală. Durata terapiei și terapiile combinate au fost eterogene, pacienții primind și exerciții convenționale de fizioterapie, terapie cu oglindă sau terapie robotică. Concluzii: Terapia VR pare să îmbunătățească funcționarea pacienților și influențează pozitiv reabilitarea extremităților superioare la pacienții post-AVC, în special în asociere cu kinetoterapie convențională.

Digital health solutions have experienced an essential expansion during the COVID-19 pandemic. Digitization contributes to ensuring the continuity of care for people and offers the possibility of more accessible access to information related to the patient, facilitates communication and can be a way to provide medical services through telemedicine. This work aims to identify the potential of the digitization of physiotherapy services. 17 physiotherapists from Romania completed a questionnaire with ten items. The results showed that although physiotherapists consider themselves prepared for computer systems, their use in medical practice mainly relates to communication with colleagues and other medical specialties.