Background: With the development of the electronics manufacturing industry, the demand for human resources has increased, which has also led to the frequent occurrence of multi-site work-related musculoskeletal disorders. Method: The participants (n = 7307) were recruited from 30 enterprises in China in 2018. The prevalence of musculoskeletal disorders was estimated using a modified Chinese version of the Musculoskeletal Disorders Questionnaire. The multivariate logistic regression model was applied to evaluate the effects of risk factors on multi-site musculoskeletal symptoms. Additionally, the log-binomial model was established to examine the correlation between the various sites of musculoskeletal symptoms in the body. Results: The 12-month prevalence of musculoskeletal symptoms among participants was 40.6%. The proportion of musculoskeletal symptoms involving single-site and 2/>2 body sites were 11.6% and 29.0%, respectively. The results of logistic regression showed that female adults who smoked, had >5-year job tenure, and always stood or sat for long period at work had a higher risk in 2/>2 body sites of musculoskeletal symptoms (p < 0.05). However, physical exercise during leisure time and “Squatting or kneeling for long period at work” were more frequently protective factors. Furthermore, the log-binomial model indicated that the neck and shoulder were significantly related to each other (Prevalence Ratio, PR: 5.511 and 7.017). Conclusions: Several demographic characteristics and work-related factors were associated with multi-site musculoskeletal symptoms in the electronics manufacturing industry in China. Improving the levels of physical exercise and reducing posture problems and force loads may help to promote the health of workers.