Melina Fatseas

Prof. Dr. Melina Fatseas


Research Focus & Metrics

Academic Career Length

24Years (2003-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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28 September 2020 in Nutrients
Verified
Journal Article
Open access
PDF file
LBLéna Bourdier
Léna Bourdier
MFMelina Fatseas
Melina Fatseas
AMAnne-Solène Maria
Anne-Solène Maria
ACArnaud Carré
Arnaud Carré
SBSylvie Berthoz
Sylvie Berthoz
The aim of the study was to examine the extent to which obese people differ in their emotionally driven and addictive-like eating behaviors from normal-weight and overweight people. A total of 1142 participants were recruited from a general population, by a web-based cross-sectional survey assessing anxiety/depression (Hospital Anxiety and Depression Scale), emotional eating (Emotional Appetite Questionnaire), food addiction (modified Yale Food Addiction Scale), and intuitive eating (Intuitive Eating Scale-2). The statistical design was based on analyses of (co)variance, correlograms, and mediations. A set of Body Mass Index (BMI) group comparisons showed that obese people reported higher levels of depression and emotional eating and that they experienced more severe and frequent food addiction symptoms than overweight and normal-weight people. Associations between anxiety, depression, food addiction symptoms’ count, and the difficulties to rely on hunger and satiety cues were found across all weight classes, suggesting that addictive-like eating may represent a unique phenotype of problematic eating behavior that is not synonymous with high BMI or obesity. Conversely, the interrelation between anxiety/depression, emotional eating, and the difficulties to rely on hunger and satiety cues was found only among obese participants, and negative emotional eating mediated the association between depression and anxiety and the difficulties to rely on hunger and satiety cues. This study emphasizes the necessity to develop more comprehensive approaches integrating emotional dysregulation and addictive-like eating behaviors to improve weight management and quality of life of obese people.

1 May 2016 in Psychiatry Research
Verified
Journal Article
Closed access
MFMelina Fatseas
Melina Fatseas
JAJean-Marc Alexandre
Jean-Marc Alexandre
JVJean-Luc Vénisse
Jean-Luc Vénisse
LRLucia Romo
Lucia Romo
MVMarc Valleur
Marc Valleur
Marie Grall-BronnecMarie Grall-Bronnec
Marie Grall-Bronnec

14 December 2021 in Frontiers in Psychiatry
Verified
Journal Article
Open access
FRFabien Renaud
Fabien Renaud
LJLouise Jakubiec
Louise Jakubiec
JSJoel Swendsen
Joel Swendsen
MFMelina Fatseas
Melina Fatseas
The frequent co-occurrence of post-traumatic stress disorder (PTSD) and substance use disorders (SUDs) leads to manifestations of both conditions that are more severe and more resistance to treatment than single disorders. One hypothesis to explain this synergy is the impact of intrusive memories on craving which, in turn, increases the risk of relapse among patients with substance use disorders. The aim of this systematic review is to examine this possibility by assessing the impact of PTSD and its symptoms on craving among dual disorder patients. Using PRISMA criteria, four databases were comprehensively searched up to June, 2021, in order to identify all candidate studies based on broad key words. Resulting studies were then selected if they examined the impact of PTSD or PTSD symptoms on craving, and if they used standardized assessments of PTSD, SUD, and craving. Twenty-seven articles matched the selection criteria and were included in this review. PTSD was found to be significantly associated with increased craving levels among patients with alcohol, cannabis, cocaine, tobacco, and other substance use disorders. Exposition to traumatic cues among dual disorder patients was also shown to trigger craving, with an additive effect on craving intensity when exposure to substance-related cues occurred. In addition, certain studies observed a correlation between PTSD symptom severity and craving intensity. Concerning mechanisms underlying these associations, some findings suggest that negative emotional states or emotion dysregulation may play a role in eliciting craving after traumatic exposure. Moreover, these studies suggest that PTSD symptoms may, independently of emotions, act as powerful cues that trigger craving. These findings argue for the need of dual disorder treatment programs that integrate PTSD-focused approaches and emotion regulation strategies, in addition to more traditional interventions for craving management.

16 July 2023 in Addictive Behaviors Reports
Verified
Journal Article
Open access
NPNatasha Pistre
Natasha Pistre
Benoit SchreckBenoit Schreck
Benoit Schreck
Marie Grall-BronnecMarie Grall-Bronnec
Marie Grall-Bronnec
MFMelina Fatseas
Melina Fatseas
• There is ongoing debate regarding addiction criteria of problematic sex use. • Impaired control and craving are highly prevalent among problematic sex users. • Impaired control and intensity of craving are predictive to problematic sex use. • Craving for sex is associated to unregulated use, frequency and quantity of use. • Anti-craving interventions could be effective in improving clinical outcomes.

28 October 2022 in Biomedicines
Verified
Journal Article
Open access
PDF file
LJLouise Jakubiec
Louise Jakubiec
VCValentine Chirokoff
Valentine Chirokoff
MAMajd Abdallah
Majd Abdallah
ESErnesto Sanz-Arigita
Ernesto Sanz-Arigita
MDMaud Dupuy
Maud Dupuy
MFMelina Fatseas
Melina Fatseas
Deficits in neurocognitive functioning are trait-like vulnerabilities that have been widely studied in persons with substance use disorders (SUD), but their role in the craving–use association and relapse vulnerability remains poorly understood. The main objectives of this study were to examine whether executive capacities moderate the magnitude of the craving–substance use relationship, and if this influence is correlated with the functional connectivity of cerebral networks, combining rsfMRI examinations and ecological momentary assessment (EMA). Eighty-six patients beginning outpatient treatment for alcohol, tobacco or cannabis addiction and 40 healthy controls completed neuropsychological tests followed by EMA to collect real-time data on craving. Fifty-four patients and 30 healthy controls also completed a resting-state fMRI before the EMA. Among the patients with SUD, better verbal fluency and resistance to interference capacities were associated with a greater propensity to use substances when the individual was experiencing craving. Preliminary rsfMRI results identified specific networks that interacted with executive performance capacities to influence the magnitude of the craving–use association. Individuals with better executive functioning may be more prone to relapse after craving episodes. Specifically, better resistance to interference and cognitive flexibility skills may reduce attention to distracting stimuli, leading to a greater awareness of craving and susceptibility to use substances.