Evolution in the fields of science and technology has led to the development of newer applications based on Artificial Intelligence (AI) technology that have been widely used in medical sciences. AI-technology has been employed in a wide range of applications related to the diagnosis of oral diseases that have demonstrated phenomenal precision and accuracy in their performance. The aim of this systematic review is to report on the diagnostic accuracy and performance of AI-based models designed for detection, diagnosis, and prediction of dental caries (DC). Eminent electronic databases (PubMed, Google scholar, Scopus, Web of science, Embase, Cochrane, Saudi Digital Library) were searched for relevant articles that were published from January 2000 until February 2022. A total of 34 articles that met the selection criteria were critically analyzed based on QUADAS-2 guidelines. The certainty of the evidence of the included studies was assessed using the GRADE approach. AI has been widely applied for prediction of DC, for detection and diagnosis of DC and for classification of DC. These models have demonstrated excellent performance and can be used in clinical practice for enhancing the diagnostic performance, treatment quality and patient outcome and can also be applied to identify patients with a higher risk of developing DC.

Artificial intelligence (AI) is a new breakthrough in technological advancements based on the concept of simulating human intelligence. These emerging technologies highly influence the diagnostic process in the field of medical sciences, with enhanced accuracy in diagnosis. This review article intends to report on the trends and application of AI models designed for diagnosis and treatment planning in orthodontics. A data search for the original research articles that were published over the last 22 years (from 1 January 2000 until 31 August 2022) was carried out in the most renowned electronic databases, which mainly included PubMed, Google Scholar, Web of Science, Scopus, and Saudi Digital Library. A total of 56 articles that met the eligibility criteria were included. The research trend shows a rapid increase in articles over the last two years. In total: 17 articles have reported on AI models designed for the automated identification of cephalometric landmarks; 12 articles on the estimation of bone age and maturity using cervical vertebra and hand-wrist radiographs; two articles on palatal shape analysis; seven articles for determining the need for orthodontic tooth extractions; two articles for automated skeletal classification; and 16 articles for the diagnosis and planning of orthognathic surgeries. AI is a significant development that has been successfully implemented in a wide range of image-based applications. These applications can facilitate clinicians in diagnosing, treatment planning, and decision-making. AI applications are beneficial as they are reliable, with enhanced speed, and have the potential to automatically complete the task with an efficiency equivalent to experienced clinicians. These models can prove as an excellent guide for less experienced orthodontists.

Automatic age estimation has garnered significant interest among researchers because of its potential practical uses. The current systematic review was undertaken to critically appraise developments and performance of AI models designed for automated estimation using dento-maxillofacial radiographic images. In order to ensure consistency in their approach, the researchers followed the diagnostic test accuracy guidelines outlined in PRISMA-DTA for this systematic review. They conducted an electronic search across various databases such as PubMed, Scopus, Embase, Cochrane, Web of Science, Google Scholar, and the Saudi Digital Library to identify relevant articles published between the years 2000 and 2024. A total of 26 articles that satisfied the inclusion criteria were subjected to a risk of bias assessment using QUADAS-2, which revealed a flawless risk of bias in both arms for the patient-selection domain. Additionally, the certainty of evidence was evaluated using the GRADE approach. AI technology has primarily been utilized for automated age estimation through tooth development stages, tooth and bone parameters, bone age measurements, and pulp–tooth ratio. The AI models employed in the studies achieved a remarkably high precision of 99.05% and accuracy of 99.98% in the age estimation for models using tooth development stages and bone age measurements, respectively. The application of AI as an additional diagnostic tool within the realm of age estimation demonstrates significant promise.

Background: In recent years, there has been remarkable growth in AI-based applications in healthcare, with a significant breakthrough marked by the launch of large language models (LLMs) such as ChatGPT and Google Bard. Patients and health professional students commonly utilize these models due to their accessibility. The increasing use of LLMs in healthcare necessitates an evaluation of their ability to generate accurate and reliable responses. Objective: This study assessed the performance of LLMs in answering orthodontic-related queries through a systematic review and meta-analysis. Methods: A comprehensive search of PubMed, Web of Science, Embase, Scopus, and Google Scholar was conducted up to 31 October 2024. The quality of the included studies was evaluated using the Prediction model Risk of Bias Assessment Tool (PROBAST), and R Studio software (Version 4.4.0) was employed for meta-analysis and heterogeneity assessment. Results: Out of 278 retrieved articles, 10 studies were included. The most commonly used LLM was ChatGPT (10/10, 100% of papers), followed by Google’s Bard/Gemini (3/10, 30% of papers), and Microsoft’s Bing/Copilot AI (2/10, 20% of papers). Accuracy was primarily evaluated using Likert scales, while the DISCERN tool was frequently applied for reliability assessment. The meta-analysis indicated that the LLMs, such as ChatGPT-4 and other models, do not significantly differ in generating responses to queries related to the specialty of orthodontics. The forest plot revealed a Standard Mean Deviation of 0.01 [CI: 0.42–0.44]. No heterogeneity was observed between the experimental group (ChatGPT-3.5, Gemini, and Copilot) and the control group (ChatGPT-4). However, most studies exhibited a high PROBAST risk of bias due to the lack of standardized evaluation tools. Conclusions: ChatGPT-4 has been extensively used for a variety of tasks and has demonstrated advanced and encouraging outcomes compared to other LLMs, and thus can be regarded as a valuable tool for enhancing educational and learning experiences. While LLMs can generate comprehensive responses, their reliability is compromised by the absence of peer-reviewed references, necessitating expert oversight in healthcare applications.

Oral diseases are the most prevalent chronic childhood diseases, presenting as a major public health issue affecting children of all ages in the developing and developed countries. Early detection and control of these diseases is very crucial for a child’s oral health and general wellbeing. The aim of this systematic review is to assess the performance of artificial intelligence models designed for application in pediatric dentistry. A systematic search of the literature was conducted using different electronic databases, primarily (PubMed, Scopus, Web of Science, Embase, Cochrane) and secondarily (Google Scholar and the Saudi Digital Library) for studies published from 1 January 2000, until 20 July 2022, related to the research topic. The quality of the twenty articles that satisfied the eligibility criteria were critically analyzed based on the QUADAS-2 guidelines. Artificial intelligence models have been utilized for the detection of plaque on primary teeth, prediction of children’s oral health status (OHS) and treatment needs (TN); detection, classification and prediction of dental caries; detection and categorization of fissure sealants; determination of the chronological age; determination of the impact of oral health on adolescent’s quality of life; automated detection and charting of teeth; and automated detection and classification of mesiodens and supernumerary teeth in primary or mixed dentition. Artificial intelligence has been widely applied in pediatric dentistry in order to help less-experienced clinicians in making more accurate diagnoses. These models are very efficient in identifying and categorizing children into various risk groups at the individual and community levels. They also aid in developing preventive strategies, including designing oral hygiene practices and adopting healthy eating habits for individuals.

The technological advancements in the field of medical science have led to an escalation in the development of artificial intelligence (AI) applications, which are being extensively used in health sciences. This scoping review aims to outline the application and performance of artificial intelligence models used for diagnosing, treatment planning and predicting the prognosis of orthognathic surgery (OGS). Data for this paper was searched through renowned electronic databases such as PubMed, Google Scholar, Scopus, Web of science, Embase and Cochrane for articles related to the research topic that have been published between January 2000 and February 2022. Eighteen articles that met the eligibility criteria were critically analyzed based on QUADAS-2 guidelines and the certainty of evidence of the included studies was assessed using the GRADE approach. AI has been applied for predicting the post-operative facial profiles and facial symmetry, deciding on the need for OGS, predicting perioperative blood loss, planning OGS, segmentation of maxillofacial structures for OGS, and differential diagnosis of OGS. AI models have proven to be efficient and have outperformed the conventional methods. These models are reported to be reliable and reproducible, hence they can be very useful for less experienced practitioners in clinical decision making and in achieving better clinical outcomes.