Prof. Gennaro De Pascale is an Associate Professor at the School of Anesthesia and Intensive Care, the Catholic University of the Sacred Heart, Italy. He works as First Level Medical Director at UOC Anesthesia, Intensive Care and Clinical Toxicology and Head of UOS Antibiotic Stewardship and Infection Control in Intensive Care. His research interests include risk factors, management and outcome of sepsis and septic shock, difficulty in treating infections, multidrug resistance, biomarkers of infection, microbiome, blood purification techniques, and ventilatory support.