The objectives of this study were to analyse the capacity of different anthropometric indices to predict vascular ageing and this association in Spanish adult population without cardiovascular disease. A total of 501 individuals without cardiovascular disease residing in the capital of Salamanca (Spain) were selected (mean age: 55.9 years, 50.3% women), through stratified random sampling by age and sex. Starting from anthropometric measurements such as weight, height, and waist circumference, hip circumference, or biochemical parameters, we could estimate different indices that reflected general obesity, abdominal obesity, and body fat distribution. Arterial stiffness was evaluated by measuring carotid-femoral pulse wave velocity (cf-PWV) using a SphygmoCor^® device. Vascular ageing was defined in three steps: Step 1: the participants with vascular injury were classified as early vascular ageing (EVA); Step 2: classification of the participants using the 10 and 90 percentiles of cf-PWV in the study population by age and sex in EVA, healthy vascular ageing (HVA) and normal vascular ageing (NVA); Step 3: re-classification of participants with arterial hypertension or type 2 diabetes mellitus included in HVA as NVA. The total prevalence of HVA and EVA was 8.4% and 21.4%, respectively. All the analysed anthropometric indices, except waist/hip ratio (WHpR), were associated with vascular ageing. Thus, as the values of the different anthropometric indices increase, the probability of being classified with NVA and as EVA increases. The capacity of the anthropometric indices to identify people with HVA showed values of area under the curve (AUC) ≥ 0.60. The capacity to identify people with EVA, in total, showed values of AUC between 0.55 and 0.60. In conclusion, as the values of the anthropometric indices increased, the probability that the subjects presented EVA increased. However, the relationship of the new anthropometric indices with vascular ageing was not stronger than that of traditional parameters. Therefore, BMI and WC can be considered to be the most useful indices in clinical practice to identify people with vascular ageing in the general population.

Background/Objectives: Protein–energy wasting (PEW) is a common complication in patients with chronic kidney disease (CKD) receiving renal replacement therapy by dialyses. This condition is associated with higher morbidity, mortality, and poorer quality of life. The aim of this systematic review was to evaluate the effectiveness of different nutritional strategies—such as oral nutritional supplements and intra-dialytic parenteral nutrition—in improving the nutritional status of these patients. Methods: A systematic review was carried out in accordance with the PRISMA statement. Searches were performed in PubMed, BVS, and Scopus between January and March 2025. Randomised or controlled clinical trials published in English or Spanish, available in full text, involving adults on haemodialysis (HD) or peritoneal dialyses (PD) were included. Fourteen studies met the inclusion criteria. Results: The nutritional interventions assessed produced consistent benefits in biochemical markers (e.g., serum albumin), muscle mass, inflammatory indices, and perceived quality of life. Intra-dialytic supplementation and multidisciplinary management were particularly effective in patients with moderate-to-severe malnutrition. Conclusions: Malnutrition is frequent and clinically significant in dialyses patients. Nutritional strategies—including oral supplementation, IDPN, and personalised counselling—effectively prevent and treat PEW. Early, tailored, evidence-based, and multidisciplinary implementation could decisively improve clinical prognosis and quality of life in this population.

Background: The ageing of the population and the progressive increase in chronic diseases represent a major challenge for healthcare systems. The community nurse case manager (CNCM) is emerging as a key figure to provide comprehensive and continued care for complex and pluripathological chronic patients (CPCPs), especially after hospital discharge. Objective: The aim of this study is to pilot CNCMs in assisting CPCPs and assess their effects on functional capacity, cognitive performance, quality of life, readmissions, clinical parameters, satisfaction with home care, and caregiver overload. Methods: A comparative study will be carried out at two health centres in Salamanca (Spain). In both centres, CPCPs will continue to receive the interventions included in the Castilla y León Health System Portfolio from their primary care (PC) nurses. In the intervention centre, case management provided by a CNCM will be added. We will recruit 212 CPCPs with cardiac or respiratory disease and/or diabetes mellitus who are dependent for basic activities of daily living and have a programmed hospital discharge. An initial assessment will be performed at home after discharge, followed by assessments at 3, 6, and 12 months. Expected results: The intervention is anticipated to improve all study outcomes. Discussion: CNCMs may contribute to more proactive and individualised follow-up care for CPCPs and their caregivers, improving care coordination. Conclusions: This study will help to evaluate the feasibility and clinical relevance of incorporating the CNCM’s role into PC. This study was registered at ClinicalTrials.gov with the identifier NCT06155591. The date of trial registration was 24 November 2023.

Introduction: Persistent COVID-19 is associated with microvascular dysfunction, with retinal vessels as potential early biomarkers. Obesity, particularly visceral adiposity, contributes to this dysfunction; however, the body mass index (BMI) is limited in its ability to assess it. Therefore, more precise alternative anthropometric indices have been proposed, although their relationship with retinal vascular caliber in persistent COVID-19 has not been studied. Objective: To analyze the relationship between different anthropometric measurements and the caliber of retinal vessels in an adult population with persistent COVID-19. Materials and Methods: This was an observational, descriptive, and cross-sectional study and included individuals diagnosed with persistent COVID-19. Retinal images were obtained using a non-mydriatic retinograph. The anthropometric variables used included: waist and hip circumference, BMI, waist-to-height ratio (WHtR), Body Roundness Index (BRI), Abdominal Volume Index (AVI), and body composition parameters measured by bioelectrical impedance analysis. Results: The sample included 284 participants (mean age: 52.7 years; 31.8% men). Men exhibited greater general and abdominal adiposity. The AV Index was negatively associated with various anthropometric indicators (BMI, BRI, waist circumference, and AVI), while venular caliber showed positive associations with all these indices, except for BMI (p < 0.05 for all). No significant correlations were found between anthropometric values and arteriolar caliber. These associations persisted after adjusting for age, sex, and pharmacological treatment. Conclusions: Individuals with obesity are associated with alterations in retinal vessels in patients with persistent COVID-19, evidenced by an increase in venous caliber and a decrease in the AV Index. However, these findings should be interpreted cautiously.

Poor sleep quality is associated with obesity, cardiovascular disease, cognitive impairment, increased hospitalization and mortality. Combining actigraphy with questionnaires effectively evaluates sleep. Age and sex shape both subjective sleep quality and objective actigraphic metrics; however, stratified estimates combining both approaches in Spanish adults are scarce. The aim of this study was to analyse the role of age and sex on sleep quality, in an age-sex stratified random sample of the general Spanish population. For this, it was carried out a cross-sectional descriptive study carried out in Salamanca and Ávila (Spain). The study population included a sample of 500 people aged 25-65 years selected by stratified random sampling by age and sex. Sleep quality was analysed using actigraphy and the Pittsburgh Sleep Quality Index-PSQI. Sociodemographic and clinical variables were also studied. The results were that men obtained a lower mean PSQI score than women. By age group, the poorer subjective sleep quality corresponded to the 25-years group, whereas the 45-year group had the lowest PSQI scores. Actigraphy showed higher efficiency in women. Men had more WASO, more awakenings and higher fragmentation. Midlife groups (35-45 years) showed lower efficiency and higher WASO. Trial registration number: NCT05324267.

Correction on: Murillo-Zaldívar AM, Alonso-Domínguez R, González-Sánchez J, Vicente-García T, Recio-Rodríguez JI, Barbero-Iglesias FJ, Sánchez-Tocino ML, García-Barrueco L, García-Oterino M and González-Manzano S (2026) Effect of a multicomponent intervention on adherence to the Mediterranean diet in older adults: a randomized controlled trial. Front. Nutr. 13:1918299. doi: 10.3389/fnut.2026.1918299 Wrong contentThe figure captions were in the wrong order in the published version of this paper. The caption of Figure 1 was incorrectly assigned to Figure 2, and the caption of Figure 2 Reminder: Figures, tables, and images will be published under a Creative Commons CC-BY license and permission must be obtained for use of copyrighted material from other sources (including republished/adapted/modified/partial figures and images from the internet). It is the responsibility of the authors to acquire the licenses, to follow any citation instructions requested by third-party rights holders, and cover any supplementary charges.