We propose a modified population-based susceptible-exposed-infectious-recovered (SEIR) compartmental model for a retrospective study of the COVID-19 transmission dynamics in India during the first wave. We extend the conventional SEIR methodology to account for the complexities of COVID-19 infection, its multiple symptoms, and transmission pathways. In particular, we consider a time-dependent transmission rate to account for governmental controls (e.g., national lockdown) and individual behavioral factors (e.g., social distancing, mask-wearing, personal hygiene, and self-quarantine). An essential feature of COVID-19 that is different from other infections is the significant contribution of asymptomatic and pre-symptomatic cases to the transmission cycle. A Bayesian method is used to calibrate the proposed SEIR model using publicly available data (daily new tested positive, death, and recovery cases) from several Indian states. The uncertainty of the parameters is naturally expressed as the posterior probability distribution. The calibrated model is used to estimate undetected cases and study different initial intervention policies, screening rates, and public behavior factors, that can potentially strike a balance between disease control and the humanitarian crisis caused by a sudden strict lockdown.
Firefighters have demanding jobs, requiring high levels of fitness in stressful situations for operational readiness, yet many firefighters are at an increased risk of developing cardiovascular disease (CVD). Diet is an important factor contributing to the development of CVD. The purpose of this study was to describe the dietary intake of firefighters and examine the associations between dietary intake and the CVD risk. Forty-six male career firefighters (age = 41.2 ± 11.2 years; BMI = 29.2 ± 4.1 kg/m2; body fat = 21.7 ± 6.1%) enrolled in a fitness-focused wellness program completed a health survey and a fitness assessment. The survey responses and fitness assessment were used to calculate the Framingham CVD Risk Score. Data were analyzed using R, the residual assumptions were verified, and the alpha level was set at 0.05. The results revealed that firefighters consume a standard American diet, with the overconsumption of meat and underconsumption of fruits and vegetables. The average CVD risk approached the upper limit of low risk. The results also indicate that meat servings and preparation fat affect the CVD risk (R2 = 0.21, p = 0.006). The outcomes of this study can inform investigations aimed at improving operational readiness and reducing the CVD risk in firefighters by implementing a holistic approach combining dietary interventions with physical training.