Zhenzhang Li

Prof. Zhenzhang Li

orcid

Research Focus & Metrics

Academic Career Length

9Years (2018-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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25 May 2021 in Scientific Reports
Verified
Journal Article
Open access
PDF file
XZXinyu Zeng
Xinyu Zeng
ZJZifan Jiang
Zifan Jiang
WLWen Luo
Wen Luo
HLHonggui Li
Honggui Li
HLHongye Li
Hongye Li
ZLZhenzhang Li
Zhenzhang Li
Early detection and appropriate medical treatment are of great use for ear disease. However, a new diagnostic strategy is necessary for the absence of experts and relatively low diagnostic accuracy, in which deep learning plays an important role. This paper puts forward a mechanic learning model which uses abundant otoscope image data gained in clinical cases to achieve an automatic diagnosis of ear diseases in real time. A total of 20,542 endoscopic images were employed to train nine common deep convolution neural networks. According to the characteristics of the eardrum and external auditory canal, eight kinds of ear diseases were classified, involving the majority of ear diseases, such as normal, Cholestestoma of the middle ear, Chronic suppurative otitis media, External auditory cana bleeding, Impacted cerumen, Otomycosis external, Secretory otitis media, Tympanic membrane calcification. After we evaluate these optimization schemes, two best performance models are selected to combine the ensemble classifiers with real-time automatic classification. Based on accuracy and training time, we choose a transferring learning model based on DensNet-BC169 and DensNet-BC1615, getting a result that each model has obvious improvement by using these two ensemble classifiers, and has an average accuracy of 95.59%. Considering the dependence of classifier performance on data size in transfer learning, we evaluate the high accuracy of the current model that can be attributed to large databases. Current studies are unparalleled regarding disease diversity and diagnostic precision. The real-time classifier trains the data under different acquisition conditions, which is suitable for real cases. According to this study, in the clinical case, the deep learning model is of great use in the early detection and remedy of ear diseases.


31 December 2024 in npj Digital Medicine
Verified
Journal Article
Open access
PDF file
YYYubiao Yue
Yubiao Yue
XZXinyu Zeng
Xinyu Zeng
HLHuanjie Lin
Huanjie Lin
JXJialong Xu
Jialong Xu
FZFan Zhang
Fan Zhang
ZLZhenzhang Li
Zhenzhang Li
Nasal endoscopy is crucial for the early detection of nasopharyngeal carcinoma (NPC), but its accuracy relies heavily on the clinician’s expertise, posing challenges for primary healthcare providers. Here, we retrospectively analysed 39,340 nasal endoscopic white-light images from three high-incidence NPC centres, utilising eight advanced deep learning models to develop an Internet-enabled smartphone application, “Nose-Keeper”, that can be used for early detection of NPC and five prevalent nasal diseases and assessment of healthy individuals. Our app demonstrated a remarkable overall accuracy of 92.27% (95% Confidence Interval (CI): 90.66%–93.61%). Notably, its sensitivity and specificity in NPC detection achieved 96.39% and 99.91%, respectively, outperforming nine experienced otolaryngologists. Explainable artificial intelligence was employed to highlight key lesion areas, improving Nose-Keeper’s decision-making accuracy and safety. Nose-Keeper can assist primary healthcare providers in diagnosing NPC and common nasal diseases efficiently, offering a valuable resource for people in high-incidence NPC regions to manage nasal cavity health effectively.

17 April 2024 in iScience
Verified
Journal Article
Open access
YYYubiao Yue
Yubiao Yue
MJMinghua Jiang
Minghua Jiang
XZXinyue Zhang
Xinyue Zhang
JXJialong Xu
Jialong Xu
HYHuacong Ye
Huacong Ye
YLYang Li
Yang Li
Swift and accurate diagnosis for earlier-stage monkeypox (mpox) patients is crucial to avoiding its spread. However, the similarities between common skin disorders and mpox and the need for professional diagnosis unavoidably impaired the diagnosis of earlier-stage mpox patients and contributed to mpox outbreak. To address the challenge, we proposed “Super Monitoring”, a real-time visualization technique employing artificial intelligence (AI) and Internet technology to diagnose earlier-stage mpox cheaply, conveniently, and quickly. Concretely, AI-mediated “Super Monitoring” (mpox-AISM) integrates deep learning models, data augmentation, self-supervised learning, and cloud services. According to publicly accessible datasets, mpox-AISM’s Precision, Recall, Specificity, and F1-score in diagnosing mpox reach 99.3%, 94.1%, 99.9%, and 96.6%, respectively, and it achieves 94.51% accuracy in diagnosing mpox, six like-mpox skin disorders, and normal skin. With the Internet and communication terminal, mpox-AISM has the potential to perform real-time and accurate diagnosis for earlier-stage mpox in real-world scenarios, thereby preventing mpox outbreak.

10 January 2025 in Scientific Reports
Verified
Journal Article
Open access
PDF file
YCYujun Cao
Yujun Cao
YYYubiao Yue
Yubiao Yue
XMXiaoming Ma
Xiaoming Ma
DLDi Liu
Di Liu
RNRongkai Ni
Rongkai Ni
ZLZhenzhang Li
Zhenzhang Li
Due to the lack of efficient mpox diagnostic technology, mpox cases continue to increase. Recently, the great potential of deep learning models in detecting mpox and non-mpox has been proven. However, existing methods are susceptible to interference from various noises in real-world settings, require diverse non-mpox images, and fail to detect abnormal input, which makes them unsuitable for practical deployment and application. To address these challenges, we proposed a novel strategy based on image inpainting called “Mask, Inpainting, and Measure” (MIM). In MIM’s pipeline, a generative adversarial network learns feature representations of mpox images by inpainting the masked mpox images. On this basis, MIM measure the similarity between the inpainted image and the original image to detect mpox and non-mpox. Compared with multi-class classification models, MIM can handle unknown categories and abnormal inputs more effectively. We used the recognized mpox dataset (MSLD) and a dataset containing 18 categories of non-mpox skin diseases to verify the effectiveness and robustness of MIM. Experimental results show that the average AUROC of MIM achieves 0.8237. In addition, external clinical testing further demonstrates the robustness of MIM. Importantly, we developed a free smartphone app to help the public and healthcare professionals detect mpox more conveniently.

27 October 2023 in Sustainability
Verified
Journal Article
Open access
PDF file
JZJialing Zhang
Jialing Zhang
ZCZhanxu Chen
Zhanxu Chen
AWAn Wang
An Wang
ZLZhenzhang Li
Zhenzhang Li
WWWei Wan
Wei Wan
The demand for personalized lighting environments based on households is steadily increasing among users. This article proposes a novel intelligent control system for personalized lighting in home environments, aiming to automatically capture user information, such as homecoming time and light switching behavior, in order to train a model that intelligently regulates the lights for users. Facial recognition technology is employed by this system to identify users and record their lighting data. Subsequently, nine commonly used machine learning models were evaluated, revealing that the error back-propagation neural network algorithm exhibits excellent performance in time-series analysis. The BPNN weights were optimized using genetic algorithms, resulting in an improved coefficient of determination (R2) of 0.99 for turn-on time and 0.82 for turn-off time test sets. Furthermore, testing was conducted on data collection duration which demonstrated that even with only 20 time-series data collected from new users, the model still displayed exceptional performance in training prediction tasks. Overall, this system effectively identifies users and automatically adjusts the lighting environment according to their preferences, providing comfortable and convenient lighting conditions tailored to individual needs. Consequently, a broader goal of energy conservation and environmental sustainability can be achieved.