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Dr. Vera Viktorovna Erdman
Institute of Biochemistry and Genetics - Subdivision of the Ufa Federal Research Centre of the Russian Academy of Sciences, Ufa, Bashkortostan, Russia
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Academic Career Length
14Years (2013-Present)
(Calculated once Scilit publication data is synced: current year − year of first publication + 1)
Representative Publications
View All Publications12 December 2015 in Molecular Biology Reports
Journal Article
TNTimur R. Nasibullin
Timur R. Nasibullin
Yanina TimashevaRSRegina I. Sadikova
Regina I. Sadikova
ITIlsiyar A. Tuktarova
Ilsiyar A. TuktarovaVEVera Viktorovna Erdman
Vera Viktorovna ErdmanOMOlga E. Mustafina
Olga E. Mustafina +3
30 April 2022 in Hygiene and sanitation
Journal Article
VEVera Viktorovna Erdman
Vera Viktorovna ErdmanEKEldar R. Kudoyarov
Eldar R. KudoyarovYVYana Valova
Yana ValovaDSDenis A. Smolyankin
Denis A. SmolyankinERElvira F. Repina
Elvira F. RepinaDKDenis O. Karimov
Denis O. KarimovNowadays over the world absolute and relative number of aging population dramatically increases with life expectancy up and birth rate down. Aging and senescence assessment are assumed to reflect current changes, internal degeneration and various stressors respond ability (i.e. genetic, environmental and occupational factors) of human organism. Occupational experience time is leading risk factor and indicator for accelerated aging. Last years, many reports concerning aging rate dependence on physical and chemical occupational hazardous factors were published. Summarizing this exposures and their effects on aging reviews are almost absent despite many provided studies. Overview of main occupational neuropsychiatric, physical and chemical risk factors, that causes human aging acceleration presented here. Circadian rhythm disorders, allostatic load, heat stress, local vibration, chemical effects and suspended nanoparticles (fine dust) influences on aging and such signs as Alzheimer’s disease risk increase, telomere length decrease and epigenetic changes and possible interactions between them are also briefly presented. Agricultural, industrial workers, teachers and police officers aging acceleration is detected in results of analysis of biological age markers.
1 June 2019 in Russian Journal of Genetics
Journal Article
VEVera Viktorovna Erdman
Vera Viktorovna ErdmanTNT. R. Nasibullin
T. R. Nasibullin
ITI. A. Tuktarova
I. A. Tuktarova
RSR. Sh. Somova
R. Sh. Somova
OMO. E. Mustafina
O. E. Mustafina
The aim of this study was to investigate the associations between the polymorphic loci in the JAK/STAT signaling pathway and the aging processes and longevity in the populations of ethnic...
23 September 2014 in Russian Journal of Genetics
Journal Article
TNTimur Nasibullin
Timur NasibullinYanina TimashevaITI. A. Tuktarova
I. A. TuktarovaVEVera Viktorovna Erdman
Vera Viktorovna ErdmanINI. E. Nikolaeva
I. E. Nikolaeva
OMO. E. Mustafina
O. E. MustafinaWith the intent to identify informative predictors of myocardial infarction (MI) development in an ethnically homogenous group of Russian men after MI (255 subjects) and in a corresponding control group (257 subjects), an analysis of genotype frequency distribution for polymorphic DNA markers (SNP) rs16944 (−511C>T, IL1B gene), rs1800796 (−572G>C, IL6 gene), rs1800872 (−592C>A, IL10 gene), rs3212227 (1159A>C, IL12B gene), rs1800629 (−308G>A, TNF), rs909253 (252A>G, LTA), rs767455 (36A>G, TNFRSF1A) was conducted. Using the Monte Carlo method and a Markov chain (APSampler), allele combinations associated both with decreased and increased MI risk were revealed. The most significant results were obtained for IL6*C/C (P = 3 × 10−4, OR = 6.3 CI 2.37–16.75), LTA*A + IL6*G/G (FDR = 2.3 × 10−4, OR = 0.25 CI 0.14–0.46), LTA*G/G + IL12B*A/A (FDR = 0.0053, OR = 4.92 CI 1.8–13.33), TNF*G + LTA*G/G + TNFRSF1A*A (FDR = 0.013, OR = 4.38, CI 1.6–12.01), TNFRSF1A*G + IL10*A/A + IL12B*C (FDR = 0.016, OR = 8.79, CI 2.17–35.63), TNF*G + LTA*G/G + IL10*C (FDR = 0.0105, OR = 3.54 CI 1.55–8.09).
1 April 2019 in Russian Journal of Genetics
Journal Article
Yanina TimashevaOZO. V. Zaplakhova
O. V. Zaplakhova
TNT. R. Nasibullin
T. R. Nasibullin
ITI. A. Tuktarova
I. A. Tuktarova
VEVera Viktorovna Erdman
Vera Viktorovna ErdmanOMO. E. Mustafina
O. E. Mustafina
+1
Multiple sclerosis is a chronic progressive disease of nervous system caused by a combination of genetic and environmental factors leading to the development of a complex of autoimmune and...
12 December 2014 in Clinical and Experimental Hypertension
Journal Article
Yanina TimashevaTNTimur R. Nasibullin
Timur R. Nasibullin
EIElvira B. Imaeva
Elvira B. Imaeva
VEVera Viktorovna Erdman
Vera Viktorovna Erdman
Peter KruzliakOMOlga E. Mustafina
Olga E. Mustafina +2
Essential hypertension (EH) is a common disease with a clear genetic component. Inflammation and endothelial dysfunction play a prominent role in the development of persistent blood pressure elevation. The aim of the current study was to detect an association between EH and polymorphic markers in genes encoding for molecules involved in the control of intercellular interactions during the inflammation process. We analysed SNPs in SELE, SELP, SELL, ICAM1, VEGFA, IL1B, IL6, IL10 and IL12B genes in a group of 534 men of Tatar ethnicity (217 patients with EH and 317 controls). Using a Markov chain Monte-Carlo-based approach (APSampler), we found genotype and allelic combinations associated with EH. The most significant associations were observed for SELE rs2076059*C–SELP rs6131*A–VEGFA –2549*I–IL1B rs16944*C (p = 3.42 × 10−5, FDR q = 0.035) and SELE rs2076059*C–SELP rs6131*A–IL12B rs3212227*C–IL1B rs16944*C (p = 323 × 10−4, FDR q = 0.035).
About Me
Vera Erdman, PhD, is a Senior Scientist of the Laboratory of Physiological Genetics of Institute of Biochemistry and Genetics, Ufa, Russia. Erdman graduated from the Bashkir State Paedagogical University in 1999 with a diploma of higher education in Psychology and Biology; conducted the population-based studies of genetic predictors of longevity since 2003; formed and supervised the collection of DNA and RNA samples of long-livers belonging to the largest ethnic groups of Volga-Ural region, Russia; authored more than 80 scientific publications; participated in national and international scientific events. Erdman's research interests are related to the genetic background of human longevity and age-associated diseases. At present, their scientific research focused on the study of the key genes and gene networks involved in the development of the highly adaptive phenotype of the longevity. Erdman has also achieved the following: member of the Russian Society of Medical Genetics since 2005; received the Award of The Gerontological Society of the Russian Academy of Sciences in 2007; Grant of the International Society of Hypertension in 2016; Grant of the Russian Foundation for Basic Research and Academy of Sciences of Abkhazia in 2019 and 2020; Award of Russian Society of the Medical Genetics in 2021.