Introduction and Objective: Previously, various stretching techniques were compared to study their effects on the different physiological parameters of hamstring muscles in the elderly population. There is no research that compares the immediate and long-term effects of proprioceptive neuromuscular facilitation-contract–relax (PNF-CR) and static stretching (SS) techniques on knee range of motion (ROM), hamstring flexibility, and knee flexor muscle EMG activity in the elderly. This study intends to compare the same. Methods: A total of 30 males aged 55–75 years were randomly assigned into the PNF-CR group (n = 10), SS group (n = 10), and control group (n = 10). The PNF-CR group received four trials of the contract–relax technique, the SS group received passive stretching of an 80 s duration by the therapist, and the control group received no intervention. A total of 12 sessions were given during the four-week period. Knee range of motion, electromyographic activity of the biceps femoris, and the sit-and-reach test were taken for the dominant side thrice: pre-intervention, immediately after stretching, and after the training period. Results: A statistically significant difference was observed in the maximum voluntary isometric contraction (MVIC) of biceps femoris between the PNF and the control groups (p = 0.01) after four weeks of intervention. The knee ROM and hamstring flexibility for the PNF group showed significant improvement immediately post-test (p = 0.01) and after four weeks of training (p = 0.07 and p = 0.001). SS showed significant results for both ROM and flexibility after four weeks of intervention (p = 0.001), and significant immediate post-test improvements were seen for ROM only (p = 0.007). Conclusions: PNF stretching has an immediate, as well as long-term, effect on knee ROM and hamstring flexibility, whereas it has only a long-term effect on muscle electromyographic activity. SS has an immediate, as well as long-term, effect on knee ROM and only a long-term effect on hamstring flexibility, without any immediate or long-term effects on muscle electromyographic activity.

This study aimed to assess the effects of exercise interventions of more than 8 weeks on thyroid function in adults with hypothyroidism through a systematic review and meta-analysis of randomized controlled trials. The PEDro, WOS, PubMed, Cochrane Central Register of Controlled Trials, and Scopus databases were searched for relevant articles, which then underwent standardised screening, data extraction, and bias risk assessment. A total of seven randomised controlled trials (n = 7) were included, predominantly examining 12 weeks of exercise therapy. A meta-analysis was conducted using data extracted from the included studies. Standardised mean differences were calculated for thyroid-stimulating hormone levels, and heterogeneity was assessed using the I² statistic. The certainty of evidence was evaluated using the GRADE approach. Statistically significant reductions in thyroid stimulating hormone (TSH) levels (SMD: -3.254; 95 % CI: -3.937 to -2.572; p < 0.001) and increases in thyroxine (T4) level (SMD: 1.315; 95 % CI: 0.263-2.367; p = 0.015) were noted in exercise intervention groups as compared to control groups. Heterogeneity was moderate (I² = 65.93 %, p = 0.019) and no publication bias was detected. In addition, based on GRADE assessment, the certainty of evidence was rated as moderate for the TSH outcome and very low for the T4 outcome. Findings from seven randomised controlled trials support the integration of long-term exercise as a non-pharmacological adjunct in the management of hypothyroidism. Exercise interventions, alongside conventional treatment, appear to improve thyroid function by reducing TSH and increasing T4 levels.

Chronic neck pain is a prevalent condition affecting a substantial portion of the population globally. Pressure pain threshold (PPT) evaluation using algometers offers a quantifiable and potentially reliable tool for pain assessment. However, its test-retest reliability, particularly using the Wagner algometer, requires further validation in this population. To assess the test-retest reliability of the Wagner algometer for measuring PPT in patients with chronic neck pain. A total of 100 patients with chronic neck pain underwent PPT assessment using the Wagner algometer at two time points across four muscle sites: right and left upper trapezius, and right and left levator scapulae. Intraclass correlation coefficients (ICC), standard error of measurement (SEM), and minimal detectable change (MDC) were calculated. ICC values indicated good to excellent reliability: right trapezius (0.98), left trapezius (1.00), right levator scapulae (0.88), and left levator scapulae (0.99). SEM ranged from 0 to 0.26, and MDC from 0 to 0.73. Bland-Altman plots confirmed high agreement without proportional bias. The Wagner algometer demonstrates excellent test-retest reliability for measuring PPT in chronic neck pain patients and may serve as a consistent tool for clinical pain assessment and outcome tracking when tested under required conditions.