Shengbin Zhou

Dr. Shengbin Zhou


Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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14 May 2021 in Computational and Mathematical Methods in Medicine
Verified
Journal Article
Open access
PDF file
XGXiue Gao
Xiue Gao
WXWenxue Xie
Wenxue Xie
ZWZumin Wang
Zumin Wang
BCBo Chen
Bo Chen
SZShengbin Zhou
Shengbin Zhou
Diabetes mellitus is a disease that has reached epidemic proportions globally in recent years. Consequently, the prevention and treatment of diabetes have become key social challenges. Most of the research on diabetes risk factors has focused on correlation analysis with little investigation into the causality of these risk factors. However, understanding the causality is also essential to preventing the disease. In this study, a causal discovery method for diabetes risk factors was developed based on an improved functional causal likelihood (IFCL) model. Firstly, the issue of excessive redundant and false edges in functional causal likelihood structures was resolved through the construction of an IFCL model using an adjustment threshold value. On this basis, an IFCL-based causal discovery algorithm was designed, and a simulation experiment was performed with the developed algorithm. The experimental results revealed that the causal structure generated using a dataset with a sample size of 2000 provided more information than that produced using a dataset with a sample size of 768. In addition, the causal structures obtained with the developed algorithm had fewer redundant and false edges. The following six causal relationships were identified: insulinplasma glucose concentration, plasma glucose concentrationbody mass index (BMI), triceps skin fold thicknessBMI and age, diastolic blood pressureBMI, and number of times pregnantage. Furthermore, the reasonableness of these causal relationships was investigated. The algorithm developed in this study enables the discovery of causal relationships among various diabetes risk factors and can serve as a reference for future causality studies on diabetes risk factors.

23 January 2021
Verified
Book Chapter
Closed access
PDF file
SZShengbin Zhou
Shengbin Zhou
XGXiue Gao
Xiue Gao
SCShifeng Chen
Shifeng Chen
YGYannan Gao
Yannan Gao