Marco Antonio da Costa Borges

Marco Antonio da Costa Borges

orcid

Research Focus & Metrics

Academic Career Length

8Years (2019-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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24 December 2020 in Molecules
Verified
Journal Article
Open access
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HBHélida Gomes de Oliveira Barud
Hélida Gomes de Oliveira Barud
RSRobson Silva
Robson Silva
MBMarco Antonio da Costa Borges
Marco Antonio da Costa Borges
Guillermo Raul CastroGuillermo Raul Castro
Guillermo Raul Castro
SRSidney Ribeiro
Sidney Ribeiro
Hernane Silva BarudHernane Silva Barud
Hernane Silva Barud
Bacterial cellulose (BC) is a natural polymer that has fascinating attributes, such as biocompatibility, low cost, and ease of processing, being considered a very interesting biomaterial due to its options for moldability and combination. Thus, BC-based compounds (for example, BC/collagen, BC/gelatin, BC/fibroin, BC/chitosan, etc.) have improved properties and/or functionality, allowing for various biomedical applications, such as artificial blood vessels and microvessels, artificial skin, and wounds dressing among others. Despite the wide applicability in biomedicine and tissue engineering, there is a lack of updated scientific reports on applications related to dentistry, since BC has great potential for this. It has been used mainly in the regeneration of periodontal tissue, surgical dressings, intraoral wounds, and also in the regeneration of pulp tissue. This review describes the properties and advantages of some BC studies focused on dental and oral applications, including the design of implants, scaffolds, and wound-dressing materials, as well as carriers for drug delivery in dentistry. Aligned to the current trends and biotechnology evolutions, BC-based nanocomposites offer a great field to be explored and other novel features can be expected in relation to oral and bone tissue repair in the near future.

11 February 2023 in Polymers
Verified
Journal Article
Open access
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MBMarco Antonio da Costa Borges
Marco Antonio da Costa Borges
ASAmanda Rinaldi Sorigotti
Amanda Rinaldi Sorigotti
RPRafaella Takehara Paschoalin
Rafaella Takehara Paschoalin
JJJosé Alberto Paris Júnior
José Alberto Paris Júnior
LSLucas Henrique Domingos da Silva
Lucas Henrique Domingos da Silva
Hernane Silva BarudHernane Silva Barud
Hernane Silva Barud
Sterilization is a fundamental step to eliminate microorganisms prior to the application of products, especially in the food and medical industries. γ-irradiation is one of the most recommended and effective methods used for sterilization, but its effect on the properties and performance of bio-based polymers is negligible. This work is aimed at evaluating the influence of γ-radiation at doses of 5, 10, 15, 25, 30, and 40 kGy on the morphology, properties, and performance of bioplastic produced from onion bulb (Allium cepa L.), using two hydrothermal synthesis procedures. These procedures differ in whether the product is washed or not after bioplastic synthesis, and are referred to as the unwashed hydrothermally treated pulp (HTP) and washed hydrothermally treated pulp (W-HTP). The morphological analysis indicated that the film surfaces became progressively rougher and more irregular for doses above 25 kGy, which increases their hydrophobicity, especially for the W-HTP samples. In addition, the FTIR and XRD results indicated that irradiation changed the structural and chemical groups of the samples. There was an increase in the crystallinity index and a predominance of the interaction of radiation with the hydroxyl groups—more susceptible to the oxidative effect—besides the cleavage of chemical bonds depending on the γ-radiation dose. The presence of soluble carbohydrates influenced the mechanical behavior of the samples, in which HTP is more ductile than W-HTP, but γ-radiation did not cause a change in mechanical properties proportionally to the dose. For W-HTP, films there was no mutagenicity or cytotoxicity—even after γ-irradiation at higher doses. In conclusion, the properties of onion-based films varied significantly with the γ-radiation dose. The films were also affected differently by radiation, depending on their chemical composition and the change induced by washing, which influences their use in food packaging or biomedical devices.

15 November 2024 in Pharmaceutics
Verified
Journal Article
Open access
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ARAndré M. Resende
André M. Resende
BMBeatriz Alves de Miranda
Beatriz Alves de Miranda
LSLuiza Bezerra da Silva
Luiza Bezerra da Silva
AOAndressa B. Oliveira
Andressa B. Oliveira
MCMárcio Botelho de Castro
Márcio Botelho de Castro
RCRita de Cassia Campebell
Rita de Cassia Campebell
Background/Objectives: Skin injuries are common in the equine clinical practice, requiring effective treatment to support natural healing. Bacuri butter is gaining attention for its potential in wound healing and its anti-inflammatory, antimicrobial, and antioxidant properties. Natural polymers such as onion (Allium cepa) bioplastics have been investigated for their potential as occlusive dressings and for tissue regeneration. Methods: This study evaluated the healing process of experimentally induced skin wounds on horses treated with bacuri butter, washed onion film, and unwashed onion film. Clinical and histopathological analyses of the wounds were conducted in six clinically healthy horses over 28 days, with a control group receiving Ringer’s lactate solution. The onion films were produced and characterized for their chemical structure and properties, while the bacuri butter was sourced and prepared for application. Results: All treatments, including the control group, promoted wound healing without relevant differences in wound contraction rates, gross aspect, or histopathological parameters. Conclusions: Therefore, despite minor variations observed in the clinical evaluations between the treatment groups, the bacuri butter or onion biopolymer showed no significant healing effect on skin wounds in horses. Additionally, this study showed the potential of equine models in testing novel therapeutic approaches for wound healing, benefiting both veterinary and human medicine.

1 June 2019 in Journal of Cranio-Maxillofacial Surgery
Verified
Journal Article
Closed access
MBMarco Antonio da Costa Borges
Marco Antonio da Costa Borges
RMRogério Margonar
Rogério Margonar
MSMaciel Antônio Spinelli
Maciel Antônio Spinelli
ICIndira Moraes Gomes Cavalcanti
Indira Moraes Gomes Cavalcanti
GOGuilherme José Pimentel Lopes De Oliveira
Guilherme José Pimentel Lopes De Oliveira
TQThallita Pereira Queiroz
Thallita Pereira Queiroz