One of the most challenging computer vision problems in the plant sciences is the segmentation of roots and soil in X-ray tomography. So far, this has been addressed using classical image analysis methods. In this paper, we address this soil–root segmentation problem in X-ray tomography using a variant of supervised deep learning-based classification called transfer learning where the learning stage is based on simulated data. The robustness of this technique, tested for the first time with this plant science problem, is established using soil–roots with very low contrast in X-ray tomography. We also demonstrate the possibility of efficiently segmenting the root from the soil while learning using purely synthetic soil and roots.
Gait, balance, and coordination are important in the development of chronic disease, but the ability to accurately assess these in the daily lives of patients may be limited by traditional biased assessment tools. Wearable sensors offer the possibility of minimizing the main limitations of traditional assessment tools by generating quantitative data on a regular basis, which can greatly improve the home monitoring of patients. However, these commercial sensors must be validated in this context with rigorous validation methods. This scoping review summarizes the state-of-the-art between 2010 and 2020 in terms of the use of commercial wearable devices for gait monitoring in patients. For this specific period, 10 databases were searched and 564 records were retrieved from the associated search. This scoping review included 70 studies investigating one or more wearable sensors used to automatically track patient gait in the field. The majority of studies (95%) utilized accelerometers either by itself (N = 17 of 70) or embedded into a device (N = 57 of 70) and/or gyroscopes (51%) to automatically monitor gait via wearable sensors. All of the studies (N = 70) used one or more validation methods in which “ground truth” data were reported. Regarding the validation of wearable sensors, studies using machine learning have become more numerous since 2010, at 17% of included studies. This scoping review highlights the current state of the ability of commercial sensors to enhance traditional methods of gait assessment by passively monitoring gait in daily life, over long periods of time, and with minimal user interaction. Considering our review of the last 10 years in this field, machine learning approaches are algorithms to be considered for the future. These are in fact data-based approaches which, as long as the data collected are numerous, annotated, and representative, allow for the training of an effective model. In this context, commercial wearable sensors allowing for increased data collection and good patient adherence through efforts of miniaturization, energy consumption, and comfort will contribute to its future success.
Predictive maps of the final infarct may help therapeutic decisions in acute ischemic stroke patients. Our objectives were to assess whether integrating the reperfusion status into deep learning models would improve their performance, and to compare them to current clinical prediction methods. We trained and tested convolutional neural networks (CNNs) to predict the final infarct in acute ischemic stroke patients treated by thrombectomy in our center. When training the CNNs, non-reperfused patients from a non-thrombectomized cohort were added to the training set to increase the size of this group. Baseline diffusion and perfusion-weighted magnetic resonance imaging (MRI) were used as inputs, and the lesion segmented on day-6 MRI served as the ground truth for the final infarct. The cohort was dichotomized into two subsets, reperfused and non-reperfused patients, from which reperfusion status specific CNNs were developed and compared to one another, and to the clinically-used perfusion-diffusion mismatch model. Evaluation metrics included the Dice similarity coefficient (DSC), precision, recall, volumetric similarity, Hausdorff distance and area-under-the-curve (AUC). We analyzed 109 patients, including 35 without reperfusion. The highest DSC were achieved in both reperfused and non-reperfused patients (DSC = 0.44 ± 0.25 and 0.47 ± 0.17, respectively) when using the corresponding reperfusion status-specific CNN. CNN-based models achieved higher DSC and AUC values compared to those of perfusion-diffusion mismatch models (reperfused patients: AUC = 0.87 ± 0.13 vs 0.79 ± 0.17, P < 0.001; non-reperfused patients: AUC = 0.81 ± 0.13 vs 0.73 ± 0.14, P < 0.01, in CNN vs perfusion-diffusion mismatch models, respectively). The performance of deep learning models improved when the reperfusion status was incorporated in their training. CNN-based models outperformed the clinically-used perfusion-diffusion mismatch model. Comparing the predicted infarct in case of successful vs failed reperfusion may help in estimating the treatment effect and guiding therapeutic decisions in selected patients.
With the widespread development of the quantified-self movement, an increasing number of users rely on mobile applications to monitor their physical activity through their smartphones. However, granting applications a direct access to sensor data exposes users to privacy risks. In particular, motion sensor data are usually transmitted to analytics applications hosted in the cloud, which leverages on machine learning models to provide feedback on their activity status to users. In this setting, nothing prevents the service provider to infer private and sensitive information about a user such as health or demographic attributes. To address this issue, we propose DySan, a privacy-preserving framework to sanitize motion sensor data against unwanted sensitive inferences (i.e., improving privacy) while limiting the loss of accuracy on the physical activity monitoring (i.e., maintaining data utility). Our approach is inspired from the framework of Generative Adversarial Networks to sanitize the sensor data for the purpose of ensuring a good trade-off between utility and privacy. More precisely, by learning in a competitive manner several networks, DySan is able to build models that sanitize motion data against inferences on a specified sensitive attribute (e.g., gender) while maintaining an accurate activity recognition. DySan builds various sanitizing models, characterized by different sets of hyperparameters in the global loss function, to propose a transfer learning scheme over time by dynamically selecting the model which provides the best utility and privacy trade-off according to the incoming data. Experiments conducted on real datasets demonstrate that DySan can drastically limit the gender inference up to 41% (from 98% with raw data to 57% with sanitized data) while only reducing the accuracy of activity recognition by 3% (from 95% with raw data to 92% with sanitized data).
A new automatic algorithm for assessing fiber‐bundle organization in the human heart using diffusion‐tensor magnetic resonance imaging is presented. The proposed approach distinguishes from the locally “greedy” paradigm, which uses voxel‐wise seed initialization intrinsic to conventional tracking algorithms. It formulates the fiber tracking problem as the global problem of computing paths in a boolean‐weighted undirected graph, where each voxel is a vertex and each pair of neighboring voxels is connected with an edge. This leads to a global optimization task that can be solved by iterated conditional modes‐like algorithms or Metropolis‐type annealing. A new deterministic optimization strategy, namely iterated conditional modes with α‐relaxation using (t2)‐ and (t4)‐moves, is also proposed; it has similar performance to annealing but offers a substantial computational gain. This approach offers some important benefits. The global nature of our tractography method reduces sensitivity to noise and modeling errors. The discrete framework allows an optimal balance between the density of fiber bundles and the amount of available data. Besides, seed points are no longer needed; fibers are predicted in one shot for the whole diffusion‐tensor magnetic resonance imaging volume, in a completely automatic way. Magn Reson Med, 2010.