Manuella Epiney

Prof. Dr. Manuella Epiney


Research Focus & Metrics

Academic Career Length

27Years (2000-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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19 March 2008 in BMC Public Health
Verified
Journal Article
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HWHans Wolff
Hans Wolff
MEManuella Epiney
Manuella Epiney
ALAna P Lourenco
Ana P Lourenco
MCMichael C Costanza
Michael C Costanza
JDJacqueline Delieutraz-Marchand
Jacqueline Delieutraz-Marchand
OIOlivier Irion
Olivier Irion
Illegal migration is an increasing problem worldwide and the so-called undocumented migrants encounter major problems in access to prevention and health care. The objective of the study was to compare the use of preventive measures and pregnancy care of undocumented pregnant migrants with those of women from the general population of Geneva, Switzerland.

1 June 2000 in Human Reproduction
Verified
Journal Article
Open access
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MEManuella Epiney
Manuella Epiney
CBC. Bertossa
C. Bertossa
AWA. Weil
A. Weil
ACA. Campana
A. Campana
PBP. Bischof
P. Bischof
The source of CA125 synthesis is still debated. Endometrial, peritoneal, ovarian and amniotic cells have been demonstrated to produce and secrete CA125. Different studies show that the peritoneum is a source of CA125. The present study aimed at investigating in vivo and in vitro the peritoneal contribution to circulating CA125. Cultures of uterine peritoneum, abdominal peritoneum and myometrium explants were performed and CA125 measured in the culture medium. To modulate the potential production of CA125, the explants were cultured with or without cycloheximide, bacterial lipopolysaccharide (LPS) or ascitic fluid. In a prospective study, we compared a group of patients after abdominal surgery (n = 19; nine men, 10 women) with a group after extra-abdominal surgery (n = 21; 11 men, 10 women), in order to detect a postoperative increase of serum CA125. De-novo synthesis of CA125 could not be demonstrated in the cultures of uterine and abdominal peritoneum and in myometrium, but CA125 concentrations were detectable in the culture medium without being modulated by cycloheximide, LPS or ascitic fluid. After peritoneal surgery, the proportion of patients with increased serum CA125 was significantly higher (P < 0.03) after abdominal surgery as compared with extra-abdominal surgery. This is considered as indirect evidence for in-vivo production of CA125 by the peritoneum.

22 July 2019 in Reproductive Health
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Journal Article
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JSJ. Sami
J. Sami
KLKatharina Quack Loetscher
Katharina Quack Loetscher
IEI. Eperon
I. Eperon
LGL. Gonik
L. Gonik
BTBegona Martinez De Tejada
Begona Martinez De Tejada
NSN. C. Schmidt
N. C. Schmidt
Migrant mothers in high-income countries often encounter more complications during pregnancy, delivery, and the postpartum period. To enlighten health care providers concerning potential barriers, the objective of this study was to explore positive and negative experiences with maternal health services in the University Hospitals of Geneva and Zurich and to describe barriers to maternity services from a qualitative perspective. In this qualitative study, six focus groups (FGs) were conducted involving 33 women aged 21 to 40 years. All FG discussions were audio-recorded and later transcribed. Data were analysed using a thematic analysis approach assisted by the Atlas.ti qualitative data management software. Positive experiences included not only the availability of maternity services, especially during emergency situations and the postpartum period, but also the availability of specific maternity services for undocumented migrants in Geneva. Negative experiences were classified into either personal or structural barriers. On the personal level, the main barriers were a lack of social support and a lack of health literacy, whereas the main themes on the structural level were language barriers and a lack of information. Structural adaptation is necessary to meet the needs of the extremely diverse population. The needs include (1) the provision of specific information for migrant women in multiple languages, (2) the availability of trained interpreters who are easily accessible to health care providers, (3) specifically trained nurses or social assistance providers to guide migrants through the health system, and (4) a cultural competence-training programme for health care providers.

17 December 2019 in BMJ Open
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Journal Article
Open access
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VSVania Sandoz
Vania Sandoz
CDCamille Deforges
Camille Deforges
SSSuzannah Stuijfzand
Suzannah Stuijfzand
MEManuella Epiney
Manuella Epiney
YVYvan Vial
Yvan Vial
AHAntje Horsch
Antje Horsch
Introduction Emergency caesarean section (ECS) qualifies as a psychological trauma, which may result in postnatal post-traumatic stress disorder (PTSD). Maternal PTSD may not only have a significant negative impact on mother–infant interactions, but also on long-term infant development. The partner’s mental health may also affect infant development. Evidence-based early interventions to prevent the development of postpartum PTSD in mothers are lacking. Immediately after a traumatic event, memory formation is vulnerable to interference. There is accumulating evidence that a brief behavioural intervention including a visuospatial task may result in a reduction in intrusive memories of the trauma. Methods and analysis This study protocol describes a double-blind multicentre randomised controlled phase III trial testing an early brief maternal intervention including the computer game ‘Tetris’ on intrusive memories of the ECS trauma (≤1 week) and PTSD symptoms (6 weeks, primary outcome) of 144 women following an ECS. The intervention group will carry out a brief behavioural procedure including playing Tetris. The attention-placebo control group will complete a brief written activity log. Both simple cognitive tasks will be completed within the first 6 hours following traumatic childbirth. The intervention is delivered by midwives/nurses in the maternity unit. The primary outcome will be differences in the presence and severity of maternal PTSD symptoms between the intervention and the attention-placebo control group at 6 weeks post partum. Secondary outcomes will be physiological stress and psychological vulnerability, mother–infant interaction and infant developmental outcomes. Other outcomes will be psychological vulnerability and physiological regulation of the partner and their bonding with the infant, as well as the number of intrusive memories of the event. Ethics and dissemination Ethical approval was granted by the Human Research Ethics Committee of the Canton de Vaud (study number 2017–02142). Dissemination of results will occur via national and international conferences, in peer-reviewed journals, public conferences and social media. Trial registration number NCT 03576586.

24 November 2008 in BMC Public Health
Verified
Journal Article
Open access
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HWHans Wolff
Hans Wolff
ALAna Lourenço
Ana Lourenço
PBPatrick Bodenmann
Patrick Bodenmann
MEManuella Epiney
Manuella Epiney
MUMonique Uny
Monique Uny
JDJean-Bernard Dubuisson
Jean-Bernard Dubuisson
Chlamydia trachomatis infection (CTI) is the most frequent sexual transmitted disease (STI) in Switzerland but its prevalence in undocumented migrants is unknown. We aimed to compare CTI prevalence among undocumented migrants undergoing termination of pregnancy (ToP) to the prevalence among women with residency permit.

1 June 2012 in Gynecologic Oncology
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Journal Article
Closed access
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PRPascale Ribaux
Pascale Ribaux
PPPatrick Petignat
Patrick Petignat
VFV. Finci
V. Finci
FNF. Pelluard Nehmé
F. Pelluard Nehmé
DCD. Carles
D. Carles
MCM. Cohen
M. Cohen