Hansoo Park

Prof. Hansoo Park

School of Integrative Engineering, Chung-Ang University, Seoul, South Korea

Research Focus & Metrics

Academic Career Length

16Years (2011-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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5 April 2019 in Frontiers in Chemistry
Verified
Journal Article
Open access
PDF file
JVJeremy B. Vines
Jeremy B. Vines
JYJee-Hyun Yoon
Jee-Hyun Yoon
NRNa-Eun Ryu
Na-Eun Ryu
Dong LimDong Lim
Dong Lim
HPHansoo Park
Hansoo Park
Gold is a multifunctional material that has been utilized in medicinal applications for centuries because it has been recognized for its bacteriostatic, anticorrosive, and antioxidative properties. Modern medicine makes routine, conventional use of gold and has even developed more advanced applications by taking advantage of its ability to be manufactured at the nanoscale and functionalized because of the presence of thiol and amine groups, allowing for the conjugation of various functional groups such as targeted antibodies or drug products. It has been shown that colloidal gold exhibits localized plasmon surface resonance (LPSR), meaning that gold nanoparticles can absorb light at specific wavelengths, resulting in photoacoustic and photothermal properties, making them potentially useful for hyperthermic cancer treatments and medical imaging applications. Modifying gold nanoparticle shape and size can change their LPSR photochemical activities, thereby also altering their photothermal and photoacoustic properties, allowing for the utilization of different wavelengths of light, such as light in the near-infrared spectrum. By manufacturing gold in a nanoscale format, it is possible to passively distribute the material through the body, where it can localize in tumors (which are characterized by leaky blood vessels) and be safely excreted through the urinary system. In this paper, we give a quick review of the structure, applications, recent advancements, and potential future directions for the utilization of gold nanoparticles in cancer therapeutics.

30 July 2020 in Advanced Healthcare Materials
Verified
Journal Article
Closed access
PDF file
SKSe‐Jeong Kim
Se‐Jeong Kim
EKEun Mi Kim
Eun Mi Kim
MYMasaya Yamamoto
Masaya Yamamoto
HPHansoo Park
Hansoo Park
HSHeungsoo Shin
Heungsoo Shin

26 April 2016 in Macromolecular Research
Verified
Journal Article
Closed access
PDF file
SASajjad Ashraf
Sajjad Ashraf
HPHun-Kuk Park
Hun-Kuk Park
HPHansoo Park
Hansoo Park
Soo Hong LeeSoo Hong Lee
Soo Hong Lee

1 February 2016 in Osteoarthritis and Cartilage
Verified
Journal Article
Closed access
SAS. Ashraf
S. Ashraf
BCB.-H. Cha
B.-H. Cha
JKJ.-S. Kim
J.-S. Kim
JAJ. Ahn
J. Ahn
In Bo HanIn Bo Han
In Bo Han
Soo Hong LeeSoo Hong Lee
Soo Hong Lee

26 November 2022 in Biomaterials Research
Verified
Journal Article
Open access
PDF file
NBNaline Bellier
Naline Bellier
PBPhornsawat Baipaywad
Phornsawat Baipaywad
NRNaeun Ryu
Naeun Ryu
JLJae Young Lee
Jae Young Lee
HPHansoo Park
Hansoo Park
Recently, nanocarriers, including micelles, polymers, carbon-based materials, liposomes, and other substances, have been developed for efficient delivery of drugs, nucleotides, and biomolecules. This review focuses on graphene oxide (GO) and reduced graphene oxide (rGO) as active components in nanocarriers, because their chemical structures and easy functionalization can be valuable assets for in vitro and in vivo delivery. Herein, we describe the preparation, structure, and functionalization of GO and rGO. Additionally, their important properties to function as nanocarriers are presented, including their molecular interactions with various compounds, near-infrared light adsorption, and biocompatibility. Subsequently, their mechanisms and the most appealing examples of their delivery applications are summarized. Overall, GO- and rGO-based nanocomposites show great promise as multipurpose nanocarriers owing to their various potential applications in drug and gene delivery, phototherapy, bioimaging, biosensing, tissue engineering, and as antibacterial agents.

12 February 2021 in Biomaterials Research
Verified
Journal Article
Open access
PDF file
MBMallinath S. Birajdar
Mallinath S. Birajdar
HJHaejin Joo
Haejin Joo
WKWon-Gun Koh
Won-Gun Koh
HPHansoo Park
Hansoo Park
In recent years, synthetic and semi-synthetic polymer materials have been widely used in various applications. Especially concerning biomedical applications, their biocompatibility, biodegradability, and non-toxicity have increased the interest of researchers to discover and develop new products for the well-being of humanity. Among the synthetic and semi-synthetic materials, the use of natural bio-based monomeric materials presents a possible novel avenue for the development of new biocompatible, biodegradable, and non-toxic products. The purpose of this article is to review the information on the role of natural bio-based monomers in biomedical applications. Increased eco-friendliness, biocompatibility, biodegradability, non-toxicity, and intrinsic biological activity are some of the attributes which make itaconic, succinic, citric, hyaluronic, and glutamic acids suitable potential materials for biomedical applications. Herein, we summarize the most recent advances in the field over the past ten years and specifically highlight new and interesting discoveries in biomedical applications. Graphical Natural origin acid-based bio-monomers for biomedical applications