Xin Guo

Xin Guo

orcid

Research Focus & Metrics

Academic Career Length

11Years (2016-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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KYKang Yu-Ting
Kang Yu-Ting
YYyan yao
yan yao
JDJing Dou
Jing Dou
XGXin Guo
Xin Guo
SLShu-Yue Li
Shu-Yue Li
BLBo Li
Bo Li
Objective: A large number of studies have shown the adverse neonatal outcomes of maternal psychological ill health. Given the potentially high prevalence of antenatal anxiety and few studies performed among Chinese people, the authors wanted to investigate the prevalence of antenatal anxiety and associated factors among pregnant women and to provide scientific basis to reduce prenatal anxiety effectively. Methods: A cross-sectional study was carried out at the Changchun Gynecology and Obstetrics Hospital from January 2015 to march 2015, with 467 participants of at least 38 weeks’ gestation enrolled. Antenatal anxiety was measured using the Self-Rating Anxiety Scale (SAS). χ2 test and logistic regression analysis were performed to evaluate the association of related factors of antenatal anxiety. Results: Among the 467 participants, the prevalence of antenatal anxiety was 20.6% (96 of 467). After adjustment for women’s socio-demographic characteristics (e.g., area, age, household income), multivariate logistical regression analysis revealed that antenatal anxiety showed significant relationship with education level lower than middle school (years ≤ 9), expected natural delivery, anemia during pregnancy, pregnancy-induced hypertension syndrome, disharmony in family relationship and life satisfaction. Conclusions: It is important to prevent or reduce antenatal anxiety from occurring by improving the health status of pregnant women and strengthening prenatal-related education and mental intervention.

21 May 2018 in Scientific Reports
Verified
Journal Article
Open access
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YLYaogai Lv
Yaogai Lv
YYyan yao
yan yao
JYJunsen Ye
Junsen Ye
XGXin Guo
Xin Guo
JDJing Dou
Jing Dou
LJLina Jin
Lina Jin
Hypertension and diabetes mellitus (DM) have become major public health issues, and previous studies have shown that there is an association between hypertension and DM. However, there is a lack of detailed information about this association. This study aimed to explore how different blood pressure (BP) levels were associated with fasting blood glucose (FBG) levels. A cross-sectional survey with adults aged 18 to 79 years was conducted in Jilin Province, China in 2012. Lambda-mu-sigma (LMS) was used to preliminarily explore the associations of BP with FBG. Quantile regression (QR) was performed to identify the specific associations by adjusting for confounding factors. The distributions of systolic blood pressure (SBP) (χ2 = 710.76, P < 0.001) and diastolic blood pressure (DBP) (χ2 = 460.20, P < 0.001) were different according to gender. LMS showed that the associations of BP with FBG became stronger when the FBG levels were close to 5.6 mmol/L. QR showed that FBG was positively associated with SBP (P30 to P90) and DBP (P20 to P90) in males. In females, FBG was positively associated with SBP from only P85 to P90. In summary, FBG was positively associated with BP in a gender-dependent manner.

5 June 2018 in Scientific Reports
Verified
Journal Article
Open access
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LJLina Jin
Lina Jin
XGXin Guo
Xin Guo
JDJing Dou
Jing Dou
BLBinghui Liu
Binghui Liu
JWJiangzhou Wang
Jiangzhou Wang
YYyan yao
yan yao
Non-communicable diseases (NCDs) are great challenges in public health, where cardiovascular diseases (CVD) accounted for the large part of mortality that caused by NCDs. Multimorbidity is very common in NCDs especially in CVD, thus multimorbidity could make NCDs worse and bring heavy economic burden. This study aimed to explore the multimorbidity among adults, especially the important role of CVD that played in the entire multimorbidity networks. A total of 21435 participants aged 18–79 years old were recruited in Jilin province in 2012. Weighted networks were adopted to present the complex relationships of multimorbidity, and Charlson Comorbidity Index (CCI) was used to evaluate the burden of multimorbidity. The prevalence of CVD was 14.97%, where the prevalence in females was higher than that in males (P < 0.001), and the prevalences of CVD increased with age (from 2.22% to 38.38%). The prevalence of multimorbidity with CVD was 96.17%, and CVD could worsen the burden of multimorbidity. Multimorbidity and multimorbidity with CVD were more marked in females than those in males. And the prevalence of multimorbidity was the highest in the middle-age, while the prevalence of multimorbidity with CVD was the highest in the old population.

XGXin Guo
Xin Guo
LSLi Shen
Li Shen
JDJing Dou
Jing Dou
YLYaogai Lv
Yaogai Lv
AZAnning Zhang
Anning Zhang
YYyan yao
yan yao
Background: Diabetes mellitus (DM) has become a major public health problem in China. Although a number of researchers have investigated DM risk factors, little is known about the associations between values of fasting blood glucose (FBG) and influencing factors. This study aims to explore these associations by the quantile regression (QR) model. Methods: A cross-sectional survey based on a sample of 23,050 adults aged 18 to 79 years was conducted in Jilin in 2012, and some subjects were excluded due to missing values with respect to necessary variables or having glycemic control, in accordance with the purposes of this study. Finally, in total 14,698 people were included in this study. QR was performed to identify the factors influencing the level of FBG in different quantiles of FBG. Results: The distribution of FBG status was different between males and females (χ2 = 175.30, p < 0.001). The QR model provided more detailed views on the associations of FBG with different factors and revealed apparent quantile-related patterns separately for different factors. Body mass index (BMI) was positively associated with the low and middle quantiles of FBG. Waist circumference (WC) had a positive association with the high quantiles of FBG. Conclusions: FBG had a positive association with BMI in normal FBG, and a positive association with WC in high FBG. Diet and alcohol intake were associated with FBG in normal FBG. FBG was more likely to be elevated in the elderly, female workers, and people with family history of DM.

6 April 2021 in Genes & Genomics
Verified
Journal Article
Closed access
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KLKexin Li
Kexin Li
LSLi Shen
Li Shen
PZPingping Zheng
Pingping Zheng
YWYanjun Wang
Yanjun Wang
LWLijuan Wang
Lijuan Wang
YYyan yao
yan yao