This research develops the TB/non-TB detection and drug-resistant categorization diagnosis decision support system (TB-DRC-DSS). The model is capable of detecting both TB-negative and TB-positive samples, as well as classifying drug-resistant strains and also providing treatment recommendations. The model is developed using a deep learning ensemble model with the various CNN architectures. These architectures include EfficientNetB7, mobileNetV2, and Dense-Net121. The models are heterogeneously assembled to create an effective model for TB-DRC-DSS, utilizing effective image segmentation, augmentation, and decision fusion techniques to improve the classification efficacy of the current model. The web program serves as the platform for determining if a patient is positive or negative for tuberculosis and classifying several types of drug resistance. The constructed model is evaluated and compared to current methods described in the literature. The proposed model was assessed using two datasets of chest X-ray (CXR) images collected from the references. This collection of datasets includes the Portal dataset, the Montgomery County dataset, the Shenzhen dataset, and the Kaggle dataset. Seven thousand and eight images exist across all datasets. The dataset was divided into two subsets: the training dataset (80%) and the test dataset (20%). The computational result revealed that the classification accuracy of DS-TB against DR-TB has improved by an average of 43.3% compared to other methods. The categorization between DS-TB and MDR-TB, DS-TB and XDR-TB, and MDR-TB and XDR-TB was more accurate than with other methods by an average of 28.1%, 6.2%, and 9.4%, respectively. The accuracy of the embedded multiclass model in the web application is 92.6% when evaluated with the test dataset, but 92.8% when evaluated with a random subset selected from the aggregate dataset. In conclusion, 31 medical staff members have evaluated and utilized the online application, and the final user preference score for the web application is 9.52 out of a possible 10.

Urban transportation systems in tourism-centric cities face challenges from rapid urbanization and population growth. Efficient, resilient, and sustainable bus route optimization is essential to ensure reliable service, minimize environmental impact, and maintain safety standards. This study presents a novel Hybrid Reinforcement Learning-Variable Neighborhood Strategy Adaptive Search (H-RL-VaNSAS) algorithm for multi-objective urban bus route optimization. Our mathematical model maximizes resilience, sustainability, tourist satisfaction, and accessibility while minimizing total travel distance. H-RL-VaNSAS is evaluated against leading optimization methods, including the Crested Porcupine Optimizer (CPO), Krill Herd Algorithm (KHA), and Salp Swarm Algorithm (SSA). Using metrics such as Hypervolume and the Average Ratio of Pareto Optimal Solutions, H-RL-VaNSAS demonstrates superior performance. Specifically, H-RL-VaNSAS achieved the highest resilience index (550), sustainability index (370), safety score (480), tourist preferences score (300), and accessibility score (2300), while minimizing total travel distance to 950 km. Compared to other methods, H-RL-VaNSAS improved resilience by 12.24–17.02%, sustainability by 5.71–12.12%, safety by 4.35–9.09%, tourist preferences by 7.14–13.21%, accessibility by 4.55–9.52%, and reduced travel distance by 9.52–17.39%. This research offers a framework for designing efficient, resilient, and sustainable public transit systems that align with urban planning and transportation goals. The integration of reinforcement learning with VaNSAS significantly enhances optimization capabilities, providing a valuable tool for mathematical and urban transportation research communities.

A person infected with drug-resistant tuberculosis (DR-TB) is the one who does not respond to typical TB treatment. DR-TB necessitates a longer treatment period and a more difficult treatment protocol. In addition, it can spread and infect individuals in the same manner as regular TB, despite the fact that early detection of DR-TB could reduce the cost and length of TB treatment. This study provided a fast and effective classification scheme for the four subtypes of TB: Drug-sensitive tuberculosis (DS-TB), drug-resistant tuberculosis (DR-TB), multidrug-resistant tuberculosis (MDR-TB), and extensively drug-resistant tuberculosis (XDR-TB). The drug response classification system (DRCS) has been developed as a classification tool for DR-TB subtypes. As a classification method, ensemble deep learning (EDL) with two types of image preprocessing methods, four convolutional neural network (CNN) architectures, and three decision fusion methods have been created. Later, the model developed by EDL will be included in the dialog-based object query system (DBOQS), in order to enable the use of DRCS as the classification tool for DR-TB in assisting medical professionals with diagnosing DR-TB. EDL yields an improvement of 1.17–43.43% over the existing methods for classifying DR-TB, while compared with classic deep learning, it generates 31.25% more accuracy. DRCS was able to increase accuracy to 95.8% and user trust to 95.1%, and after the trial period, 99.70% of users were interested in continuing the utilization of the system as a supportive diagnostic tool.

Generative artificial intelligence (GenAI) may assist evidence-informed health-policy work, but favorable user perceptions and well-written outputs do not establish factual reliability or implementation readiness. A multilevel mixed-methods pilot evaluation examined MUSYA AI, a locally grounded policy-support platform in Thailand. Thirty-five health-sector personnel completed questionnaires, seven participated in Think-Aloud observation, sixteen Policy Briefs were assessed using an expert rubric, and seventy factual claims underwent evidence auditing. The document comparison included eight MUSYA AI and eight ChatGPT (GPT-5.6, OpenAI) outputs under common task instructions and system-specific information access. Mean System Usability Scale, perceived usefulness, and trust scores were 97.29/100, 4.70/5, and 4.57/5, respectively. Ceiling effects and limited internal consistency constrained interpretation of these descriptive indices; user experience, ease of use, and behavioral intention were interpreted at the item level. Observations documented reading and editing, but successful error detection and correction were not evaluated. MUSYA AI documents received higher overall quality ratings than comparator documents (95.38 ± 2.39 versus 72.25 ± 11.90; difference, 23.13 points; bootstrap 95% confidence interval, 15.63–31.38; Hedges’ g = 2.55). However, classification–rationale inconsistencies affected forty-five claims (64.3%), leaving comparative factual-accuracy findings provisional. The small, nonrandomized document sample and absence of verified task pairing prevented causal attribution of quality differences. MUSYA AI elicited favorable pilot-user perceptions and produced higher-rated documents within the evaluated sample. These findings support continued supervised evaluation; institutional readiness requires traceable claim adjudication, demonstrated oversight effectiveness, and broader controlled assessment.