As one of the most promising thermal management solutions, spray cooling has the advantages of high heat-transfer coefficient and maintaining a low temperature of the cooling surface. By summarizing the influential factors and practical applications of spray cooling, the current challenges and bottlenecks were indicated so as to prompt its potential applications in the future. Firstly, this paper reviewed the heat-transfer mechanism of spray cooling and found that spray cooling is more advantageous for heat dissipation in high-power electronic devices by comparing it with other cooling techniques. Secondly, the latest experimental studies on spray cooling were reviewed in detail, especially the effects of spray parameters, types of working fluid, surface modification, and environmental parameters on the performance of cooling system. Afterwards, the configuration and design of the spray cooling system, as well as its applications in the actual industry (data centers, hybrid electric vehicles, and so on) were enumerated and summarized. Finally, the scientific challenges and technical bottlenecks encountered in the theoretical research and industrial application of spray cooling technology were discussed, and the direction of future efforts were reasonably speculated.

Real-time monitoring of blood flow and thrombosis formation induced by laser irradiation is critical to reveal the thermal-damage mechanism and successfully implement vascular-dermatology laser surgery. Laser speckle contrast imaging (LSCI) is a non-invasive technique to visualize perfusion in various tissues. However, the ability of the LSCI to monitor the transient thermal response of blood vessels, especially thrombus formation during laser irradiation, requires further research. In this paper, an LSCI system was constructed and a 632 nm He-Ne laser was employed to illuminate a Sprague Dawley rat dorsal skin chamber model irradiated by a 1064 nm Nd: YAG therapy laser. The anisotropic diffusion filtering (ADF) technique is implemented after temporal LSCI (tLSCI) processing to improve the SNR and temporal resolution. The speckle flow index is used to characterize the blood-flow velocity to reduce the computational cost. The combination of the tLSCI and ADF increases the temporal resolution by five times and the SNR by 17.2 times and 16.14 times, without and with laser therapy, respectively. The laser-induced thrombus formation and vascular damage during laser surgery can be visualized without any exogenous labels, which provides a powerful tool for thrombus monitoring during laser surgery.

To investigate the spray cooling characteristics and the impact of spray parameters such as chamber pressure, spray height, and spray tilt angle on heat transfer efficiency, a mathematical model based on the Eulerian–Lagrangian frame was established for an R410A closed-loop spray cooling system. The results revealed that the spray pattern is conical, with the center velocity significantly higher than the edge velocity. The temperature distribution of the cooling surface and liquid film height both exhibit a “W” shape, and the surface temperature is lower where the liquid film is thin. There is an optimal liquid film height of approximately 5 μm, at which the cooling surface temperature is the lowest. The surface temperature increases with an increase in the spray chamber pressure. Considering average cooling surface temperature, the optimal tilt angle is 40° with an average surface temperature of 330.1 K. When considering wall temperature and wall heat transfer coefficient uniformity, however, the optimal tilt angle is 10°, leading to the average surface temperature of 332.6 K. When increasing the optimal spray height to 70 mm, the average surface temperature is 313.4 K.