After receiving their PhD degree from the Chinese Academy of Sciences, Shanghai Institute of Materia Medica in 2015, Lesha Zhang worked in the Department of Physiology, School of Basic Medicine, Anhui Medical University as a lecturer till now. During this time, they once studied in Xue’s lab at the university of science and technology of China for 1 year and visited the university of Tasmania for 3 months. Their research interest focuses on investigating the role of opioid receptors in cerebral ischemic stroke and its therapeutic targets. Another research interest includes discovering the action of cerebral vascular smooth muscle cells and endothelial cells in cardiovascular diseases based on genetic sequencing analysis. They participate in the Anhui Provincial Association of Physiological Sciences.