Prashant Upadhyay

Dr. Prashant Upadhyay


Research Focus & Metrics

Academic Career Length

5Years (2022-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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3 November 2022 in Cancers
Verified
Journal Article
Open access
PDF file
OBOthman Bin-Alamer
Othman Bin-Alamer
LBLokeshwar Bhenderu
Lokeshwar Bhenderu
PPPaolo Palmisciano
Paolo Palmisciano
KBKishore Balasubramanian
Kishore Balasubramanian
PUPrashant Upadhyay
Prashant Upadhyay
AHAli S. Haider
Ali S. Haider
Background: Infratemporal fossa (ITF) tumors represent various pathologies and are seldom described in the literature, reflecting their rarity. Here we review the literature on tumors invading ITF and describe patient characteristics, treatment strategies, and clinical outcomes. Methods: Relevant articles were retrieved from PubMed, Scopus, and Cochrane. A systematic review and meta-analysis were conducted on the clinical presentation, treatment protocols, and clinical outcomes. Result: A total of 27 articles containing 106 patients with ITF tumors (median tumor size: 24.3 cm3 [interquartile range, 15.2–42 cm3]) were included (median age: 46 years [interquartile range, 32–55 years]; 59.4% were males]). Of the confirmed tumor pathology data, schwannomas (n = 24; 26.1%) and meningiomas (n = 13; 14.1%) were the most common tumors. Facial hypoesthesia (n = 22; 18.5%), auricular/preauricular pain (n = 20; 16.8%), and headaches (n = 11; 9.2%) were the most common presenting symptoms. Of patients who had surgical resection (n = 97; 95.1%), 70 (73.7%) had transcranial surgery (TCS) and 25 (26.3%) had endoscopic endonasal surgery (EES). Among available details on the extent of resection (n = 84), gross-total resection (GTR) was achieved in 62 (73.8%), and 5 (6.0%) had biopsy only. Thirty-five (33.0%) patients had postoperative complications. Among cases with available data on reconstruction techniques (n = 8), four (50%) had adipofascial antero-lateral thigh flap, three (37.5%) had latissimus dorsi free flap, and one (12.5%) had antero-lateral thigh flap. Fourteen (13.2%) patients had adjuvant chemotherapy, and sixteen (15.1%) had adjuvant radiotherapy. During a median follow-up time of 28 months (IQR, 12.25–45.75 months), 15 (14.2%) patients had recurrences, and 18 (17.0%) patients died. The median overall survival (OS) time was 36 months (95% confidence interval: 29–41 months), and the 5-year progression-free survival (PFS) rate was 61%. Conclusion: Various tumor types with different biological characteristics invade the ITF. The present study describes patient demographics, clinical presentation, management, and outcomes. Depending on the tumor type and patient condition, patient-tailored management is recommended to optimize treatment outcomes.

15 September 2024 in Journal of Minimally Invasive Surgery
Verified
Journal Article
Open access
PDF file
MHMuad Haidar
Muad Haidar
NSNuha Ahmed H Sharaf
Nuha Ahmed H Sharaf
SSSuha Abdullah Saleh
Suha Abdullah Saleh
PUPrashant Upadhyay
Prashant Upadhyay
Muad Gamil M Haidar, Nuha Ahmed H Sharaf, Suha Abdullah Saleh, Prashant Upadhyay. Journal of Minimally Invasive Surgery 2024;27:156-64. https://doi.org/10.7602/jmis.2024.27.3.156

1 February 2023 in International Journal of Surgery
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Journal Article
Open access
DMDattatreya Mukherjee
Dattatreya Mukherjee
PUPrashant Upadhyay
Prashant Upadhyay
NMNobendu Mukerjee
Nobendu Mukerjee
SJSri Mbbs Jamya
Sri Mbbs Jamya
APAnuj Paul
Anuj Paul
PBPuspendu Biswas
Puspendu Biswas

1 January 2024
Verified
Book Chapter
Open access
Harendra KumarHarendra Kumar
Harendra Kumar
DMDattatreya Mukherjee
Dattatreya Mukherjee
PMPronoy Mukherjee
Pronoy Mukherjee
SBSumitaksha Banerjee
Sumitaksha Banerjee
PUPrashant Upadhyay
Prashant Upadhyay
TSTanmay Sanyal
Tanmay Sanyal
Green surgery, a concept aiming at improving sustainability in the healthcare industry, has become practically important due to the increasing environmental impact of typical surgical procedures. The following chapter thoroughly examines the environmental issues associated with traditional surgical procedures, such as waste creation, large energy consumption, excessive water use, and the release of harmful chemicals and anesthetics. This book provides fundamental concepts of green surgery, such as material reduction, reuse, and recycling, focusing on energy efficiency, water conservation, and sustainable procurement. A comprehensive analysis of realistic strategies for implementing these principles is provided, emphasising waste management, energy and water conservation, and emission reduction. Furthermore, the chapter discusses the problems and impediments to green surgery, such as institutional opposition, financial concerns, and regulatory limits, and provides solutions to overcome them. This chapter includes case studies and success stories from prominent hospitals that demonstrate new technology and practices that have effectively reduced the environmental impact of surgical procedures. This chapter emphasizes the importance of sustainability in ensuring the long-term well-being of patients and the environment by promoting a collaborative effort to adopt more environmentally friendly surgical practices.

15 August 2024 in Clinical Case Reports
Verified
Journal Article
Open access
AKAshok Kumar
Ashok Kumar
PUPrashant Upadhyay
Prashant Upadhyay
Harendra KumarHarendra Kumar
Harendra Kumar
DMDattatreya Mukherjee
Dattatreya Mukherjee
DTDivyansh Tiwari
Divyansh Tiwari
AAAymar Akilimali
Aymar Akilimali
Key Clinical Message: This is a challenging case where the surgeon has initially thought it is a gallbladder (GB) mucocele. The surprise finding of a mucocele during an emergency laparotomy highlights the deceptive nature of certain clinical manifestations within the hepatobiliary domain. The intraoperative discovery of a 1×1 cm GB hole on the right lateral wall of the GB fundus revealed an unexpected and significant deviation from the hypothesized pathogenesis. This case report provides a complicated diagnosis scenario for a hepatobiliary illness aggravated by schizophrenia. Arriving with frequent nausea and vomiting, a 70‐year‐old female patient with schizophrenia missed typical symptoms of gallbladder (GB) disease, including fever and stomach discomfort. This odd look and corroborative imaging showing a cystic lesion in the right belly led to a diagnostic suspicion of a sizable GB mucocele. But a surprising result from an emergency laparotomy revealed a significant GB perforation, different from the previous diagnosis. This case highlights the difficulties in identifying atypical GB diseases, particularly in individuals with mental comorbidities that could conceal or alter the expression of physical symptoms. To confirm or rule out differential diagnosis and allow early and tailored treatments, it emphasizes the need for thorough diagnostic tests, including a complete clinical history, physical examinations, laboratory analysis, imaging modalities, and surgical procedures. This case emphasizes the importance of careful examination in complex medical contexts by stressing the requirement of thorough assessments and comprehensive diagnostic frameworks in navigating challenging clinical situations.