Periyar Selvam Sellamuthu

Dr. Periyar Selvam Sellamuthu

Department of Food Process Engineering, SRM Institute of Science & Technology, Chengalpattu, India
orcid

Research Focus & Metrics

Academic Career Length

14Years (2013-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 May 2022 in Food Chemistry
Verified
Journal Article
Closed access
Anand Babu PerumalAnand Babu Perumal
Anand Babu Perumal
LHLingxia Huang
Lingxia Huang
Reshma B NambiarReshma B Nambiar
Reshma B Nambiar
Yong HeYong He
Yong He
Xiaoli LiXiaoli Li
Xiaoli Li
Periyar Selvam SellamuthuPeriyar Selvam Sellamuthu
Periyar Selvam Sellamuthu

1 January 2022 in Chemosphere
Verified
Journal Article
Closed access
Anand Babu PerumalAnand Babu Perumal
Anand Babu Perumal
Reshma B NambiarReshma B Nambiar
Reshma B Nambiar
Periyar Selvam SellamuthuPeriyar Selvam Sellamuthu
Periyar Selvam Sellamuthu
Rotimi SadikuRotimi Sadiku
Rotimi Sadiku
Xiaoli LiXiaoli Li
Xiaoli Li
Yong HeYong He
Yong He



1 October 2018 in Process Biochemistry
Verified
Journal Article
Closed access
Reshma B NambiarReshma B Nambiar
Reshma B Nambiar
Periyar Selvam SellamuthuPeriyar Selvam Sellamuthu
Periyar Selvam Sellamuthu
Anand Babu PerumalAnand Babu Perumal
Anand Babu Perumal
Rotimi SadikuRotimi Sadiku
Rotimi Sadiku
GPGoitse Phiri
Goitse Phiri
JJJ. Jayaramudu
J. Jayaramudu

12 September 2013 in ISRN Pharmacology
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Journal Article
Open access
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Periyar Selvam SellamuthuPeriyar Selvam Sellamuthu
Periyar Selvam Sellamuthu
APArulselvan Palanisamy
Arulselvan Palanisamy
KSKamalraj Subban
Kamalraj Subban
SFSharida Fakurazi
Sharida Fakurazi
MKMurugesan Kandasamy
Murugesan Kandasamy
Oxidative stress plays an important role in the progression of diabetes complications. The aim of the present study was to investigate the beneficial effect of oral administration of mangiferin in streptozotocin (STZ)-induced diabetic rats by measuring the oxidative indicators in liver and kidney as well as the ameliorative properties. Administration of mangiferin to diabetic rats significantly decreased blood glucose and increased plasma insulin levels. The activities of antioxidant enzymes superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) and level of reduced glutathione (GSH) were significantly (P<0.05) decreased while increases in the levels of lipidperoxidation (LPO) markers were observed in liver and kidney tissues of diabetic control rats as compared to normal control rats. Oral treatment with mangiferin (40 mg/kg b.wt/day) for a period of 30 days showed significant ameliorative effects on all the biochemical and oxidative parameters studied. Diabetic rats treated with mangiferin restored almost normal architecture of liver and kidney tissues, which was confirmed by histopathological examination. These results indicated that mangiferin has potential ameliorative effects in addition to its antidiabetic effect in experimentally induced diabetic rats.