Tuğba Onur

Dr. Tuğba Onur

orcid

Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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9 June 2022 in Journal of Cardiac Surgery
Verified
Journal Article
Closed access
TOTuğba Onur
Tuğba Onur
ÜKÜmran Karaca
Ümran Karaca
FAFiliz Ata
Filiz Ata
HSHalil E. Sayan
Halil E. Sayan
AOANIL ONUR
ANIL ONUR
CECüneyt Eriş
Cüneyt Eriş

23 August 2023 in Children
Verified
Journal Article
Open access
PDF file
ADAsiye Demirel
Asiye Demirel
SOSeyda Ozgunay
Seyda Ozgunay
ŞEŞermin Eminoğlu
Şermin Eminoğlu
ABAYŞE NESLİHAN BALKAYA
AYŞE NESLİHAN BALKAYA
TOTuğba Onur
Tuğba Onur
MGMehmet Gamlı
Mehmet Gamlı
Anesthesia-related complications, such as pulmonary aspiration of gastric contents, occur in approximately 0.02–0.1% of elective pediatric surgeries. Aspiration risk can be reliably assessed by ultrasound examination of the gastric antrum, making it an essential non-invasive bedside tool. In this prospective observational study, since most of our patients are immigrants and have communication problems, we wanted to investigate gastric contents and the occurrence of “high risk stomach” in children undergoing elective surgery for the possibility of pulmonary aspiration, even if the children and/or parents reported their last oral intake time. This risk is defined by ultrasound findings of solid content in the antrum and/or a calculated gastric volume exceeding 1.25 mL/kg. Children aged 2–18 were included in the study. Both supine and right lateral decubitus (RLD) ultrasound examinations were performed on the antrum before surgery. Using a qualitative grading scale from 0 to 2, we evaluated the gastric fluid content. The cross-sectional area (CSA) of the antrum was measured in the RLD position, aiding the calculation of the gastric fluid volume according to an established formula by Perlas. Ultrasound measurements of 97 children were evaluated. The median fasting duration was 4 h for liquids and 9 h for thick liquids and solids. Solid content was absent in all the children. Five children (5.2%) exhibited a grade 2 antrum, implying that fluid content was visible in both the supine and RLD positions. The median antral CSA in the RLD was 2.36 cm2, with a median gastric volume of 0.46 mL/kg. For patients with a grade 0 antrum, a moderate and positive correlation was observed between the antral CSA and BMI, and a strong and positive correlation was evident between the antral CSA and age, similar to a grade 1 antrum. Only a single child (1%) had a potentially elevated risk of aspiration of gastric contents. Hence, the occurrence of a “high risk stomach” was 1% (95% confidence interval: 0.1–4.7%) and is consistent with the literature. As a necessary precaution, we propose the regular use of ultrasound evaluations of gastric contents, given their non-invasive, bedside-friendly, and straightforward implementation, for identifying risks when fasting times are uncertain and for ruling out unknown risk factors in each potential patient.

11 February 2025 in Medical Science Monitor
Verified
Journal Article
Open access
BÖBuket Özyaprak
Buket Özyaprak
YAYılmaz Apaydın
Yılmaz Apaydın
ŞBŞule Balk
Şule Balk
MGMehmet Gamlı
Mehmet Gamlı
AIAbdulkadir İsKender
Abdulkadir İsKender
NKNail Kahraman
Nail Kahraman
BACKGROUND Acute renal failure (ARF) is a critical complication following open-heart surgery, significantly impacting morbidity and mortality. This study aimed to evaluate the association between intraoperative renal near-infrared spectroscopy (NIRS) findings and postoperative ARF in 357 patients undergoing cardiac surgery with cardiopulmonary bypass (CPB). MATERIAL AND METHODS This prospective study included 357 patients undergoing open-heart surgery with CPB. ARF diagnosis was based on KDIGO criteria. NIRS sensors were placed bilaterally at the T12/L2 level under ultrasound guidance, and renal oxygenation (rSO2) values were continuously monitored intraoperatively. Patients were categorized into ARF and non-ARF groups for comparative analysis. RESULTS ARF developed in 12.3% (n=44) of patients. ARF patients were older (p=0.024) and had longer surgery (p<0.001), CPB (p=0.004), and aortic cross-clamping durations (p=0.013). They required more blood products (p<0.001) and intra-aortic balloon pump support (p=0.027). Intensive care unit stays were significantly longer in ARF patients (p=0.036). NIRS analysis showed significant rSO2 reductions in ARF patients. Time spent with rSO2 below 80%, 70%, and 60% was a strong predictor of ARF. Receiver operating characteristic (ROC) analyses demonstrated that time exceeding 30 minutes below the 60% threshold predicted ARF with 96.5% specificity and 86.4% sensitivity. CONCLUSIONS Intraoperative NIRS monitoring is crucial for detecting renal perfusion abnormalities during high-risk surgeries. Declines below 80%, 70%, and 60% thresholds strongly predict ARF. Timely interventions, such as fluid resuscitation and hemodynamic support, can mitigate risks. ARF patients require intensive postoperative monitoring due to prolonged ICU stays and complications.

3 January 2022 in The European Research Journal
Verified
Journal Article
Open access
PDF file
ÜKÜmran Karaca
Ümran Karaca
FAFiliz Ata
Filiz Ata
CYCanan Yilmaz
Canan Yilmaz
ABAYŞE NESLİHAN BALKAYA
AYŞE NESLİHAN BALKAYA
TOTuğba Onur
Tuğba Onur
Objectives: We aimed to evaluate the anesthetic approaches of patients who underwent surgery in our hospital during the early COVID-19 pandemic period.Methods: All patients admitted to general surgery (GS), orthopedics, neurosurgery (NS), urology, cardiovascular surgery (CVS), thoracic surgery, ear nose throat, and plastic and reconstructive surgery at the operating rooms in our hospital in early pandemic periods were scanned retrospectively. Demographical data, surgical indications, urgency, anesthetic methods, and complications are evaluated. Anesthetic methods used in the operations were examined as general anesthesia, regional anesthesia, and sedoanalgesia. In addition, patients’ hospital stay period, intensive care unit admission rate, 30 days mortality, and COVID-19 positivity after surgery were examined.Results: Two hundred and ninety patients were admitted for operation in our hospital during a pandemic. CVS, Orthopedics, and GS were departments that admitted the most number of patients with ratios of 27.2%, 26.2%, and 25.2% respectively. The patients who underwent emergency surgery were seen in the CVS with 79 patients and the orthopedics with 73 patients. In anesthesia management, the application rate of general anesthesia was 44.1%, regional anesthesia 33.1%, and sedoanalgesia 22.8%. Totally 61 patients were admitted to ICU. According to surgical branches, 30-day mortality rates were determined as 8.3% in NS, 6.6% in GS, 3.8% in CVS, and 2.7% in orthopedics respectively. Four patients were postoperative COVID-19 positive in total.Conclusions: Anesthetic approaches in surgical patients may affect the length of hospital stay, referral to the intensive care unit, and mortality in the early period of the COVID-19 pandemic.

3 March 2023 in The European Research Journal
Verified
Journal Article
Open access
PDF file
TOTuğba Onur
Tuğba Onur
ADAsiye Demirel
Asiye Demirel
AOANIL ONUR
ANIL ONUR
SOSeyda Ozgunay
Seyda Ozgunay
ÜKÜmran Karaca
Ümran Karaca
MEMesut Engin
Mesut Engin
Objectives: Epidural anesthesia, once considered a gold standard, has significant complications: hypotension, urinary retention, and catastrophic neurological damage in rare cases. While paravertebral analgesia can provide similar analgesic effectiveness to epidural analgesia, it is associated with fewer side effects. To compare the perioperative and postoperative effects of epidural (ED) and ultrasound-guided paravertebral block (PVB) applications in thoracotomy surgeries. Methods: Fifty-two patients underwent elective thoracotomy; Group 1 (ED, n = 23) and Group 2 (PVB, n = 29) were evaluated. A comparison of hemodynamic parameters and complications preoperatively and postoperatively, postoperative analgesia requirements, visual analog scale (VAS) pain scores within 24 hours at specified times, the amount of analgesic used, the time to mobilize, the time to discharge, and the VAS values measured at three months was made. Results: There was no difference between the study groups regarding demographic and ASA values, most comorbid chronic diseases, obesity, and smoking. The number of attempts, the postoperative 2nd hour VAS score, and the doses of paracetamol and tramadol used was significantly higher in Group 1 than in Group 2 (p = 0.002, p = 0.002, p = 0.012, and p = 0.022, respectively). There was no statistical difference between the groups in terms of postoperative 6, 12, 24 hours, and 3 months VAS scores, first mobilization and discharge, time to remove the thorax tube, intensive care (PACU) need, and perioperative and postoperative complications (p > 0.05). Conclusions: Ultrasound-guided PVB can be considered a safe and effective alternative to ED in thoracotomy surgery.

1 December 2022 in Bagcilar Medical Bulletin
Verified
Journal Article
Closed access
ADAsiye Demirel
Asiye Demirel
ABAYŞE NESLİHAN BALKAYA
AYŞE NESLİHAN BALKAYA
TOTuğba Onur
Tuğba Onur
SOSeyda Ozgunay
Seyda Ozgunay