Zdeněk Hon

Dr. Zdeněk Hon

orcid

Research Focus & Metrics

Academic Career Length

20Years (2007-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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8 April 2015 in Sustainability
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Journal Article
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ZHZdeněk Hon
Zdeněk Hon
JÖJan Österreicher
Jan Österreicher
LNLeos Navratil
Leos Navratil
The article summarizes contemporary scientific knowledge of depleted uranium effects on human health due to its use in military conflicts. The discussion covers cases of minimal risk due to external irradiation resulting from the storage and handling of depleted uranium ammunition and, in contrast, important toxicological and radio-toxicological risks of late effects resulting from the inhalation and ingestion of dust particles produced by the burning of the core of the anti-tank ammunition.

28 April 2016 in Molecules
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VPVladimír Pitschmann
Vladimír Pitschmann
ZHZdeněk Hon
Zdeněk Hon
Toxin weapon research, development, production and the ban on its uses is an integral part of international law, with particular attention paid to the protection against these weapons. In spite of this, hazards associated with toxins cannot be completely excluded. Some of these hazards are also pointed out in the present review. The article deals with the characteristics and properties of natural toxins and synthetic analogs potentially constituting the basis of toxin weapons. It briefly describes the history of military research and the use of toxins from distant history up to the present age. With respect to effective disarmament conventions, it mentions certain contemporary concepts of possible toxin applications for military purposes and the protection of public order (suppression of riots); it also briefly refers to the question of terrorism. In addition, it deals with certain traditional as well as modern technologies of the research, synthesis, and use of toxins, which can affect the continuing development of toxin weapons. These are, for example, cases of new toxins from natural sources, their chemical synthesis, production of synthetic analogs, the possibility of using methods of genetic engineering and modern biotechnologies or the possible applications of nanotechnology and certain pharmaceutical methods for the effective transfer of toxins into the organism. The authors evaluate the military importance of toxins based on their comparison with traditional chemical warfare agents. They appeal to the ethics of the scientific work as a principal condition for the prevention of toxin abuse in wars, military conflicts, as well as in non-military attacks.

22 January 2022 in Global Pediatric Health
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Journal Article
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GGGabriela Galková
Gabriela Galková
PBPavel Böhm
Pavel Böhm
ZHZdeněk Hon
Zdeněk Hon
THTomáš Heřman
Tomáš Heřman
RDRadan Doubrava
Radan Doubrava
LNLeoš Navrátil
Leoš Navrátil
Introduction. The disagreement of the general public’s views on home births is practically identical for the professional public and specialists also. The core of the problem lies in the disunity between individual countries of the European Union—complete prohibition under the risk of committing a crime on one side and standard procedure perceived as something completely common on the other side. Methods. The authors focused on the prevalence of home births in individual EU countries, together with the proportion of neonatological mortality compared to the number of live births, which are data that, unlike home births, are mandatory in each EU Member State. Data on home births were obtained from available official and verified sources such as the Ministry of Health, reviews published by the WHO, or published peer-reviewed scientific and professional works. Secondary data were procured via Web of Science, Scopus, or PubMed. Results. The aim of the study was to trace the documented numbers of home births in the individual states of the European Union in the years 2015 to 2019, to analyze them with data on live births together and with data on infant mortality. A comparative analysis of the compiled data can be used to conclude which countries have the highest domestic birth rates and how the birth rate is manifested in these countries. Based on the analysis of available data, it can be determined that the Netherlands, Denmark, and Germany have the highest share of domestic births. The link between home births and increased neonatal mortality has not been established. Eastern Europe countries have the highest neonatal mortality, namely Romania (1.19%) and Malta (0.63%). Conclusion. The Netherlands has the highest domestic birth rate per 100 000 inhabitants with a 5-year average of 161 922 (overall average of all live births 993.40), but is also in 11th place in neonatal mortality, together with Denmark and Belgium, which have 0.35% neonatal neonatal mortality. The country with the lowest neonatal mortality of 0.19% is Slovenia. The total average of all children born in 5 years (915 live births) is 1.422. When monitoring the number of domestic births in other countries in the years 2015 to 2019, an increasing tendency of this trend is observed.

1 January 2010 in Acta Medica (Hradec Kralove, Czech Republic)
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JPJiří Patočka
Jiří Patočka
ZHZdeněk Hon
Zdeněk Hon
Ethylene glycol is a colorless, odorless, sweet-tasting but poisonous type of alcohol found in many household products. The major use of ethylene glycol is as an antifreeze in, for example, automobiles, in air conditioning systems, in de-icing fluid for windshields, and else. People sometimes drink ethylene glycol mistakenly or on purpose as a substitute for alcohol. Ethylene glycol is toxic, and its drinking should be considered a medical emergency. The major danger from ethylene glycol is following ingestion. Due to its sweet taste, peoples and occasionally animals will sometimes consume large quantities of it if given access to antifreeze. While ethylene glycol itself has a relatively low degree of toxicity, its metabolites are responsible for extensive cellular damage to various tissues, especially the kidneys. This injury is caused by the metabolites, glycolic and oxalic acid and their respective salts, through crystal formation and possibly other mechanisms. Toxic metabolites of ethylene glycol can damage the brain, liver, kidneys, and lungs. The poisoning causes disturbances in the metabolism pathways, including metabolic acidosis. The disturbances may be severe enough to cause profound shock, organ failure, and death. Ethylene glycol is a common poisoning requiring antidotal treatment.

4 January 2023 in Toxics
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VPVladimír Pitschmann
Vladimír Pitschmann
ZHZdeněk Hon
Zdeněk Hon
The emergence of modern chemical weapons and chemical warfare is traditionally associated with World War I, but the use of poisons in the military has its roots deep in the past. The sources of these poisons have always been natural agents that also served as medicines. This relationship between poison and medicine, and nowadays between chemical warfare and medicine, or between ‘military chemistry’ and pharmacy, appears to be very important for understanding not only the history but also the possible future of both phenomena. This article looks at some historical examples of the use of drugs as chemical weapons and, conversely, the use of chemical weapons as medicines. It seeks to find answers to some questions that are particularly relevant to the implementation of the Chemical Weapons Convention, which aims to achieve a world without chemical warfare.

1 May 2015
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Conference Paper
Closed access
JSJakub Schlenker
Jakub Schlenker
VSVladimir Socha
Vladimir Socha
PSPavel Smrcka
Pavel Smrcka
KHKarel Hana
Karel Hana
VBVladimir Begera
Vladimir Begera
MVMartin Viteznik
Martin Viteznik
The article presents a FlexiGuard modular biotelemetric system for real-time monitoring of special military units. The main focus of the system is on automated monitoring of special forces via parallel monitoring of each member of the special team individually, witch includes collecting sets of physiologic (or environmental) parameters. The systems consists of a set of sensors (for monitoring temperature, heart rate, acceleration, humidity etc.) and modular sensing unit, which records the measured data and sends them to the visualization unit. The measured values (i.e. heart rate, surface temperature of the body and so on) are then visualized in the graphic user interface of the visualization unit. Testing of the functionality of the system took place in both laboratory and real environment. In the case of carrying out the measurements on 34 soldiers at series of 4 probands at the same time, the sensor networks worked without any loss of signal. During the data transfer to the visualization unit, a loss of approx 0.2% of packets occurred. The system thus can offer information to the commander, which may prove essential for the optimalization of operational strategies, taking the state of wellbeing of the team members into account.