In nuclear facilities, the mandatory atmosphere surveillance is operated by Continuous Air Monitors. This standalone instrument is designed to measure the airborne aerosol activity concentration and to trig an alarm signal when a predetermined activity concentration is exceeded. However, a rapid resuspension event of coarse aerosol leads to a measurement error: the airborne aerosol activity concentration is over-evaluated. Prior results have shown that the coarse aerosol deposit disturbs the background evaluation for the radioactivity measurement. The interactions between radioactive aerosols (with radon daughters) and coarse non-radioactive aerosols have to be investigated by running together aerosol models and nuclear simulations. Therefore, this paper investigates different ways to represent an aerosol deposit in numerical simulations. We developed two numerical aerosol deposit models that we integrated into Geant4, a tool for the simulation of the passage of radiations through matter, and then compared these to experimental results. The simplest model was discarded, and by using the second model, we managed to correctly frame our simulation results as an experimental measurement: an aerosol has been correctly considered in a nuclear simulation. By combining theory, simulations, and experimentations on both aerosol science and nuclear physics, this research will be able to improve the comprehension of monitors’ behaviour in delicate situations and, more broadly, the filtration of aerosols using radioactivity.