Quantifying the importance of nodes in complex networks is known as the problem of identifying influential nodes and is considered a critical aspect in interacting with these networks. This problem has many applications such as controlling rumors, sickness spreading, and viral marketing, where its importance has been understood by the research society in the last decade. This paper proposes a new semi-local centrality to identify influential nodes in complex networks based on the theory of Local Average Shortest Path with extended Neighborhood concept (LASPN). LASPN focuses on a distributed technique to extract the subgraph associated with each node and apply the average shortest path theory to it. We use the extended neighborhood concept to find the nearest neighbors of each node with low complexity, where this can lead to high efficiency in dealing with large-scale networks. In addition to applying relative changes in the average shortest path, the proposed metric considers the importance of the node itself as well as its nearest neighbors in ranking the nodes. Evaluation of the proposed centrality metric has been done through numerical simulations on several real-world networks. The results based on Kendall's $$\tau$$ coefficient under the SIR infection spreading model show that LASPN improves the performance by 2.7% compared to the best available equivalent method.
Cross-modal retrieval aims to search samples of one modality via queries of other modalities, which is a hot issue in the community of multimedia. However, two main challenges, i.e., heterogeneity gap and semantic interaction across different modalities, have not been solved efficaciously. Reducing the heterogeneous gap can improve the cross-modal similarity measurement. Meanwhile, modeling cross-modal semantic interaction can capture the semantic correlations more accurately. To this end, this paper presents a novel end-to-end framework, called Dual Attention Generative Adversarial Network (DA-GAN). This technique is an adversarial semantic representation model with a dual attention mechanism, i.e., intra-modal attention and inter-modal attention. Intra-modal attention is used to focus on the important semantic feature within a modality, while inter-modal attention is to explore the semantic interaction between different modalities and then represent the high-level semantic correlation more precisely. A dual adversarial learning strategy is designed to generate modality-invariant representations, which can reduce the cross-modal heterogeneity efficiently. The experiments on three commonly used benchmarks show the better performance of DA-GAN than these competitors.
Drought stress-related gene identification is vital in revealing the drought resistance mechanisms underlying rice and for cultivating rice-resistant varieties. Traditional methods, such as Genome-Wide Association Studies (GWAS), usually identify hundreds of candidate stress genes, and further validation by biological experiements is then time-consuming and laborious. However, computational and prioritization methods can effectively reduce the number of candidate stress genes. This study introduces a random walk with restart algorithm (RWR), a state-of-the-art guilt-by-association method, to operate on rice multiplex biological networks. It explores the physical and functional interactions between biological molecules at different levels and prioritizes a set of potential genes. Firstly, we integrated a Protein–Protein Interaction (PPI) network, constructed by multiple protein interaction data, with a gene coexpression network into a multiplex network. Then, we implemented the RWR on multiplex networks (RWR-M) with known drought stress genes as seed nodes to identify potential drought stress-related genes. Finally, we conducted association analysis between the potential genes and the known drought stress genes. Thirteen genes were identified as rice drought stress-related genes, five of which have been reported in the recent literature to be involved in drought stress resistance mechanisms.
The precise identification of splice sites is essential for unraveling the structure and function of genes, constituting a pivotal step in the gene annotation process. In this study, we developed a novel deep learning model, DRANetSplicer, that integrates residual learning and attention mechanisms for enhanced accuracy in capturing the intricate features of splice sites. We constructed multiple datasets using the most recent versions of genomic data from three different organisms, Oryza sativa japonica, Arabidopsis thaliana and Homo sapiens. This approach allows us to train models with a richer set of high-quality data. DRANetSplicer outperformed benchmark methods on donor and acceptor splice site datasets, achieving an average accuracy of (96.57%, 95.82%) across the three organisms. Comparative analyses with benchmark methods, including SpliceFinder, Splice2Deep, Deep Splicer, EnsembleSplice, and DNABERT, revealed DRANetSplicer’s superior predictive performance, resulting in at least a (4.2%, 11.6%) relative reduction in average error rate. We utilized the DRANetSplicer model trained on O. sativa japonica data to predict splice sites in A. thaliana, achieving accuracies for donor and acceptor sites of (94.89%, 94.25%). These results indicate that DRANetSplicer possesses excellent cross-organism predictive capabilities, with its performance in cross-organism predictions even surpassing that of benchmark methods in non-cross-organism predictions. Cross-organism validation showcased DRANetSplicer’s excellence in predicting splice sites across similar organisms, supporting its applicability in gene annotation for understudied organisms. We employed multiple methods to visualize the decision-making process of the model. The visualization results indicate that DRANetSplicer can learn and interpret well-known biological features, further validating its overall performance. Our study systematically examined and confirmed the predictive ability of DRANetSplicer from various levels and perspectives, indicating that its practical application in gene annotation is justified.
Accurate body dimension and weight measurements are critical for optimizing poultry management, health assessment, and economic efficiency. This study introduces an innovative deep learning-based model leveraging multimodal data—2D RGB images from different views, depth images, and 3D point clouds—for the non-invasive estimation of duck body dimensions and weight. A dataset of 1023 Linwu ducks, comprising over 5000 samples with diverse postures and conditions, was collected to support model training. The proposed method innovatively employs PointNet++ to extract key feature points from point clouds, extracts and computes corresponding 3D geometric features, and fuses them with multi-view convolutional 2D features. A Transformer encoder is then utilized to capture long-range dependencies and refine feature interactions, thereby enhancing prediction robustness. The model achieved a mean absolute percentage error (MAPE) of 5.73% and an R2 of 0.953 across seven morphometric parameters describing body dimensions, and an MAPE of 10.49% with an R2 of 0.952 for body weight, indicating robust and consistent predictive performance across both structural and mass-related phenotypes. Unlike conventional manual measurements, the proposed model enables high-precision estimation while eliminating the necessity for physical handling, thereby reducing animal stress and broadening its application scope. This study marks the first application of deep learning techniques to poultry body dimension and weight estimation, providing a valuable reference for the intelligent and precise management of the livestock industry with far-reaching practical significance.
As a prominent topic in food computing, cross-modal recipe retrieval has garnered substantial attention. However, the semantic alignment across food images and recipes cannot be further enhanced due to the lack of intra-modal alignment in existing solutions. Additionally, a critical issue named food image ambiguity is overlooked, which disrupts the convergence of models. To these ends, we propose a novel Multi-Modal Alignment Method for Cross-Modal Recipe Retrieval (MMACMR). To consider inter-modal and intra-modal alignment together, this method measures the ambiguous food image similarity under the guidance of their corresponding recipes. Additionally, we enhance recipe semantic representation learning by involving a cross-attention module between ingredients and instructions, which is effective in supporting food image similarity measurement. We conduct experiments on the challenging public dataset Recipe1M; as a result, our method outperforms several state-of-the-art methods in commonly used evaluation criteria.