Accurate gene prediction in metagenomics fragments is a computationally challenging task due to the short-read length, incomplete, and fragmented nature of the data. Most gene-prediction programs are based on extracting a large number of features and then applying statistical approaches or supervised classification approaches to predict genes. In our study, we introduce a convolutional neural network for metagenomics gene prediction (CNN-MGP) program that predicts genes in metagenomics fragments directly from raw DNA sequences, without the need for manual feature extraction and feature selection stages. CNN-MGP is able to learn the characteristics of coding and non-coding regions and distinguish coding and non-coding open reading frames (ORFs). We train 10 CNN models on 10 mutually exclusive datasets based on pre-defined GC content ranges. We extract ORFs from each fragment; then, the ORFs are encoded numerically and inputted into an appropriate CNN model based on the fragment-GC content. The output from the CNN is the probability that an ORF will encode a gene. Finally, a greedy algorithm is used to select the final gene list. Overall, CNN-MGP is effective and achieves a 91% accuracy on testing dataset. CNN-MGP shows the ability of deep learning to predict genes in metagenomics fragments, and it achieves an accuracy higher than or comparable to state-of-the-art gene-prediction programs that use pre-defined features.
Automatic handwriting recognition has received considerable attention over the past three decades. Handwriting recognition systems are useful for a wide range of applications. Much research has been conducted to address the problem in Latin languages. However, less research has focused on the Arabic language, especially concerning recognizing children’s Arabic handwriting. This task is essential as the demand for educational applications to practice writing and spelling Arabic letters is increasing. Thus, the development of Arabic handwriting recognition systems and applications for children is important. In this paper, we propose two deep learning-based models for the recognition of children’s Arabic handwriting. The proposed models, a convolutional neural network (CNN) and a pre-trained CNN (VGG-16) were trained using Hijja, a recent dataset of Arabic children’s handwriting collected in Saudi Arabia. We also train and test our proposed models using the Arabic Handwritten Character Dataset (AHCD). We compare the performance of the proposed models with similar models from the literature. The results indicate that our proposed CNN outperforms the pre-trained CNN (VGG-16) and the other compared models from the literature. Moreover, we developed Mutqin, a prototype to help children practice Arabic handwriting. The prototype was evaluated by target users, and the results are reported.
Computational approaches, specifically machine-learning techniques, play an important role in many metagenomic analysis algorithms, such as gene prediction. Due to the large feature space, current de novo gene prediction algorithms use different combinations of classification algorithms to distinguish between coding and non-coding sequences. In this study, we apply a filter method to select relevant features from a large set of known features instead of combining them using linear classifiers or ignoring their individual coding potential. We use minimum redundancy maximum relevance (mRMR) to select the most relevant features. Support vector machines (SVM) are trained using these features, and the classification score is transformed into the posterior probability of the coding class. A greedy algorithm uses the probability of overlapped candidate genes to select the final genes. Instead of using one model for all sequences, we train an ensemble of SVM models on mutually exclusive datasets based on GC content and use the appropriated model to classify candidate genes based on their read’s GC content. Our proposed algorithm achieves an improvement over some existing algorithms. mRMR produces promising results in gene prediction. It improves classification performance and feature interpretation. Our research serves as a basis for future studies on feature selection for gene prediction.
Recommender systems are used as effective information-filtering techniques to automatically predict and identify sets of interesting items for users based on their preferences. Recently, there have been increasing efforts to use sentiment analysis of user reviews to improve the recommendations of recommender systems. Previous studies show the advantage of integrating sentiment analysis with recommender systems to enhance the quality of recommendations and user experience. However, limited research has been focused on recommender systems for Arabic content. This study, therefore, sets out to improve Arabic recommendation systems and investigate the impact of using sentiment analysis of user reviews on the quality of recommendations. We propose two collaborative filtering recommender systems for Arabic content: the first depends on users’ ratings, and the second uses sentiment analysis of users’ reviews to enhance the recommendations. These proposed models were tested using the Large-Scale Arabic Book Reviews dataset. Our results show that, when the user review sentiment analysis is combined with recommender systems, the quality of the recommendations is improved. The best model was the singular value decomposition (SVD) with the Arabic BERT–mini model, which yielded minimum errors in terms of RMSE and MAE values and outperformed the performance of other previous studies in the literature.