Shivankar Agrawal

Dr. Shivankar Agrawal

Indian Council of Medical Research, New Delhi, Delhi, International
orcid

Research Focus & Metrics

Academic Career Length

24Years (2003-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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21 November 2017 in Frontiers in Pharmacology
Verified
Journal Article
Open access
Shivankar AgrawalShivankar Agrawal
Shivankar Agrawal
DADebabrata Acharya
Debabrata Acharya
AAAlok Adholeya
Alok Adholeya
CBColin Barrow
Colin Barrow
Sunil DeshmukhSunil Deshmukh
Sunil Deshmukh
Marine environments are largely unexplored and can be a source of new molecules for the treatment of many diseases such as malaria, cancer, tuberculosis, HIV etc. The Marine environment is one of the untapped bioresource of getting pharmacologically active nonribosomal peptides (NRPs). Bioprospecting of marine microbes have achieved many remarkable milestones in pharmaceutics. Till date, more than 50% of drugs which are in clinical use belong to the nonribosomal peptide or mixed polyketide-nonribosomal peptide families of natural products isolated from marine bacteria, cyanobacteria and fungi. In recent years large numbers of nonribosomal have been discovered from marine microbes using multi-disciplinary approaches. The present review covers the NRPs discovered from marine microbes and their pharmacological potential along with role of genomics, proteomics and bioinformatics in discovery and development of nonribosomal peptides drugs.

1 February 2018 in Phytochemistry Letters
Verified
Journal Article
Closed access
Shivankar AgrawalShivankar Agrawal
Shivankar Agrawal
AAAlok Adholeya
Alok Adholeya
CBColin Barrow
Colin Barrow
Sunil DeshmukhSunil Deshmukh
Sunil Deshmukh

1 November 2020 in South African Journal of Botany
Verified
Journal Article
Open access
Shivankar AgrawalShivankar Agrawal
Shivankar Agrawal
Sunil DeshmukhSunil Deshmukh
Sunil Deshmukh
MRM. Sudhakara Reddy
M. Sudhakara Reddy
Ram PrasadRam Prasad
Ram Prasad
MGMayurika Goel
Mayurika Goel

25 October 2016 in Frontiers in Pharmacology
Verified
Journal Article
Open access
PDF file
Shivankar AgrawalShivankar Agrawal
Shivankar Agrawal
AAAlok Adholeya
Alok Adholeya
Sunil DeshmukhSunil Deshmukh
Sunil Deshmukh
Marine biodiversity is recognized by a wide and unique array of fascinating structures. The complex associations of marine microorganisms, especially with sponges, bryozoans, and tunicates, make it extremely difficult to define the biosynthetic source of marine natural products or to deduce their ecological significance. Marine sponges and tunicates are important source of novel compounds for drug discovery and development. Majority of these compounds are nitrogen containing and belong to non-ribosomal peptide (NRPs) or mixed polyketide–NRP natural products. Several of these peptides are currently under trial for developing new drugs against various disease areas, including inflammatory, cancer, neurodegenerative disorders and infectious disease. This review features pharmacologically active NRPs from marine sponge and tunicates based on their biological activities.

17 May 2021 in Biotechnology and Applied Biochemistry
Verified
Journal Article
Closed access
PDF file
Shivankar AgrawalShivankar Agrawal
Shivankar Agrawal
SSSreeparna Samanta
Sreeparna Samanta
Sunil DeshmukhSunil Deshmukh
Sunil Deshmukh

1 November 2020 in South African Journal of Botany
Verified
Journal Article
Open access
Sunil DeshmukhSunil Deshmukh
Sunil Deshmukh
Shivankar AgrawalShivankar Agrawal
Shivankar Agrawal
VPVed Prakash
Ved Prakash
MGManish K. Gupta
Manish K. Gupta
MRM. Sudhakara Reddy
M. Sudhakara Reddy