Bridges in a marine environment have been suffering from the chloride attack for a long period of time. Due to the fact that different sections of piers may be exposed to different conditionals, the chloride‐induced corrosion not only affects the scale of the deterioration process but also significantly modifies over time the damage propagation mechanisms and the seismic damage distribution. In order to investigate the seismic damage of existing RC bridges subject to spatial chloride‐induced corrosion in a marine environment, Duracrete model is applied to determine the corrosion initiation time of reinforcing steels under different exposure conditionals and the degradation models of reinforcing steels, confined concrete, and unconfined concrete are obtained based on the previous investigation. According to the seismic fragility assessment method, the damage assessment approach for the existing RC bridges subject to spatial chloride‐induced corrosion in a marine environment is present. Moreover, a case study of a bridge under two kinds of water regions investigated the influence of spatial chloride‐induced corrosion on the seismic damage of piers and other components. The results show that the spatial chloride‐induced corrosion may result in the section at the low water level becoming more vulnerable than the adjacent sections and the alteration of seismic damage distribution of piers. The corrosion of pier will increase the seismic damage probability of itself, whereas it will result in a reduction of seismic damage probability of other components. Moreover, the alteration of seismic damage distribution of piers will amplify the effect. Due to the fact that the spatial chloride‐induced corrosion of piers may alter the yield sequence of cross section, it then affects the seismic performance assessment of piers. A method to determine the evolution probability of yield sequence of corroded piers is proposed at last. From the result, the evolution probability of yield sequence of piers in longitudinal direction depends on the relationship between the height of piers and submerged zone. Moreover, the height of piers, submerged zone, and tidal zone have a common influence on the evolution of yield sequence of piers in transversal direction.