My research is focused on cerebrovascular diseases and vascular complications associated with diabetes. I have a broad background in integrated basic and translational research projects, including extracellular exosomes and microvesicles, stem cell therapy, and the microRNAs (miRs) in ischemic stroke with diabetes. My research approaches include using transgenic mouse models in combination with animal surgeries, such as middle cerebral artery occlusion (MCAO) for inducing ischemic stroke, telemetric probe implantation for recording blood pressure and heart rate, minipump/microinjection for chronic/acute drug administration, and animal modeling for diet and brain injection-induced hemorrhagic strokes. I have also been actively involved in translational studies by investigating the role of exosomes/microvesicles in stroke and diabetic patients.