Sarah E. Finch, Jinho D. Choi. Proceedings of the 21th Annual Meeting of the Special Interest Group on Discourse and Dialogue. 2020.

Jaemin Shin, Hyungjun Yoon, Seungjoo Lee, Sungjoon Park, Yunxin Liu, Jinho Choi, Sung-Ju Lee. Proceedings of the 2023 Conference on Empirical Methods in Natural Language Processing. 2023.

Sarah E. Finch, Ellie S. Paek, Jinho D. Choi. Proceedings of the 24th Meeting of the Special Interest Group on Discourse and Dialogue. 2023.

The capabilities of natural language processing (NLP) methods have expanded significantly in recent years, and progress has been particularly driven by advances in data science and machine learning. However, NLP is still largely underused in patient-oriented clinical research and care (POCRC). A key reason behind this is that clinical NLP methods are typically developed, optimized, and evaluated with narrowly focused data sets and tasks (eg, those for the detection of specific symptoms in free texts). Such research and development (R&D) approaches may be described as problem oriented, and the developed systems perform specialized tasks well. As standalone systems, however, they generally do not comprehensively meet the needs of POCRC. Thus, there is often a gap between the capabilities of clinical NLP methods and the needs of patient-facing medical experts. We believe that to increase the practical use of biomedical NLP, future R&D efforts need to be broadened to a new research paradigm—one that explicitly incorporates characteristics that are crucial for POCRC. We present our viewpoint about 4 such interrelated characteristics that can increase NLP systems’ suitability for POCRC (3 that represent NLP system properties and 1 associated with the R&D process)—(1) interpretability (the ability to explain system decisions), (2) patient centeredness (the capability to characterize diverse patients), (3) customizability (the flexibility for adapting to distinct settings, problems, and cohorts), and (4) multitask evaluation (the validation of system performance based on multiple tasks involving heterogeneous data sets). By using the NLP task of clinical concept detection as an example, we detail these characteristics and discuss how they may result in the increased uptake of NLP systems for POCRC.

Existing Retrieval-Augmented Generation (RAG) systems face challenges in enterprise settings due to limited retrieval scope and data security risks. When relevant internal documents are unavailable, the system struggles to generate accurate and complete responses. Additionally, using closed-source Large Language Models (LLMs) raises concerns about exposing proprietary information. To address these issues, we propose the Secure Multifaceted-RAG (SecMulti-RAG) framework, which retrieves not only from internal documents but also from two supplementary sources: pre-generated expert knowledge for anticipated queries and on-demand external LLM-generated knowledge. To mitigate security risks, we adopt a local open-source generator and selectively utilize external LLMs only when prompts are deemed safe by a filtering mechanism. This approach enhances completeness, prevents data leakage, and reduces costs. In our evaluation on a report generation task in the automotive industry, SecMulti-RAG significantly outperforms traditional RAG—achieving 79.3–91.9% win rates across correctness, richness, and helpfulness in LLM-based evaluation and 56.3–70.4% in human evaluation. This highlights SecMulti-RAG as a practical and secure solution for enterprise RAG.