Mountain glaciers are known to be strongly affected by global climate change. Here we compute temporally consistent changes in glacier area, surface elevation and ice mass over the entire European Alps between 2000 and 2014. We apply remote sensing techniques on an extensive database of optical and radar imagery covering 93% of the total Alpine glacier volume. Our results reveal rapid glacier retreat across the Alps (−39 km² a⁻¹) with regionally variable ice thickness changes (−0.5 to −0.9 m a⁻¹). The strongest downwasting is observed in the Swiss Glarus and Lepontine Alps with specific mass change rates up to −1.03 m.w.e. a⁻¹. For the entire Alps a mass loss of 1.3 ± 0.2 Gt a⁻¹ (2000–2014) is estimated. Compared to previous studies, our estimated mass changes are similar for the central Alps, but less negative for the lower mountain ranges. These observations provide important information for future research on various socio-economic impacts like water resource management, risk assessments and tourism.

Glaciers are indicators of ongoing anthropogenic climate change¹. Their melting leads to increased local geohazards², and impacts marine³ and terrestrial^4,5 ecosystems, regional freshwater resources⁶, and both global water and energy cycles^7,8. Together with the Greenland and Antarctic ice sheets, glaciers are essential drivers of present^9,10 and future^11–13 sea-level rise. Previous assessments of global glacier mass changes have been hampered by spatial and temporal limitations and the heterogeneity of existing data series^14–16. Here we show in an intercomparison exercise that glaciers worldwide lost 273 ± 16 gigatonnes in mass annually from 2000 to 2023, with an increase of 36 ± 10% from the first (2000–2011) to the second (2012–2023) half of the period. Since 2000, glaciers have lost between 2% and 39% of their ice regionally and about 5% globally. Glacier mass loss is about 18% larger than the loss from the Greenland Ice Sheet and more than twice that from the Antarctic Ice Sheet¹⁷. Our results arise from a scientific community effort to collect, homogenize, combine and analyse glacier mass changes from in situ and remote-sensing observations. Although our estimates are in agreement with findings from previous assessments^14–16 at a global scale, we found some large regional deviations owing to systematic differences among observation methods. Our results provide a refined baseline for better understanding observational differences and for calibrating model ensembles^12,16,18, which will help to narrow projection uncertainty for the twenty-first century^11,12,18.

Making good decisions in extremely complex and difficult processes and situations has always been both a key task as well as a challenge in the clinic and has led to a large amount of clinical, legal and ethical routines, protocols and reflections in order to guarantee fair, participatory and up-to-date pathways for clinical decision-making. Nevertheless, the complexity of processes and physical phenomena, time as well as economic constraints and not least further endeavours as well as achievements in medicine and healthcare continuously raise the need to evaluate and to improve clinical decision-making. This article scrutinises if and how clinical decision-making processes are challenged by the rise of so-called artificial intelligence-driven decision support systems (AI-DSS). In a first step, this article analyses how the rise of AI-DSS will affect and transform the modes of interaction between different agents in the clinic. In a second step, we point out how these changing modes of interaction also imply shifts in the conditions of trustworthiness, epistemic challenges regarding transparency, the underlying normative concepts of agency and its embedding into concrete contexts of deployment and, finally, the consequences for (possible) ascriptions of responsibility. Third, we draw first conclusions for further steps regarding a ‘meaningful human control’ of clinical AI-DSS.