Background: The prevalence of overweight or obesity in women of reproductive age continues to increase. A high pre-pregnancy body mass index (BMI) has been shown to increase the risk of pregnancy complications and predispose offspring to childhood obesity. However, little is known about factors affecting women’s ability to achieve sustainable weight management and very few studies have applied behavior change theory to qualitative data.Aim: This study aimed to explore barriers and facilitators for weight management among women with overweight or obesity, who wanted to lose weight before pregnancy.Methods: We conducted semi-structured interviews with 17 women with a BMI ≥ 27 kg/m², who planned to become pregnant in the near future. Data were analyzed using an abductive approach and the Capability, Opportunity, Motivation, and Behavior model was applied as a conceptual framework.Results: The women’s strongest motivator for pre-conception weight loss was their ability to become pregnant. Barriers to successful weight management included their partners’ unhealthy behaviors, mental health challenges, competing priorities, and internalized weight stigmatization. The women described careful planning, partners’ health behaviors, social support, and good mental health as facilitators for sustainable weight management.Conclusion: Our study provides insights into factors affecting weight management among women with overweight or obesity in the pre-conception period. Future interventions on weight management require a holistic approach, including a focus on social support, especially from the partner, and mental health, as well as an effort to limit internalized weight stigma.

Research on peer support programmes for people with type 2 diabetes has shown a positive effect on health-related behaviours, yet little is known about what causes this effect. This study researched the mechanisms generating immediate outcomes (changes in awareness) and intermediate outcomes (behavioural changes) among socially vulnerable people with type 2 diabetes in a Danish peer support intervention. Using a realist-informed evaluation approach, we investigated how nonprofessional volunteers perceived and performed as peer supporters, and how these activated mechanisms in the interaction between peers and peer supporters. Furthermore, we explored how contextual factors related to peers and peer supporters influenced how mechanisms worked. The study was based on a qualitative multimethod case-study design (n=11). Data consisted of semistructured interviews with four key informants (peer, peer supporter, project manager, and a diabetes nurse) (n=27), participation observation of two peer supporter training courses, one network meeting, two supervisions for peer supporters, and logbooks from peer supporters. Data were analysed using systematic text condensation. The findings revealed that the peer supporters used their lived experience to perceive and perform in the peer support meetings. Furthermore, being with a like-minded person with type 2 diabetes activated mechanisms, such as trust, respect, empathy, care, and honesty between peers and peer supporters, which led to increased self-care awareness among the peers (immediate outcome). Finally, the findings revealed that contextual factors, such as peer supporters lived experiences and peers and peer supporters sociodemographic characteristics and health conditions, affected how the mechanisms were at stake. Thus, our study contributes on how to support socially vulnerable people with type 2 diabetes and where peer support programmes can supplement the established healthcare system by providing social and emotional support to this vulnerable group. This trial is registered with ClinicalTrials.gov, Retrospective Registration (20 Jan 2021), registration number NCT04722289.

Mexico exhibits one of the highest prevalence rates of overweight and obesity globally, accompanied by a surge in non-communicable diseases, which in turn leads to elevated mortality rates. Existing efforts to address rising obesity rates have shown limited effectiveness. Maternal weight, diet, and physical activity (PA) during pregnancy affect the mother's and offspring's health. Despite the importance of establishing and engaging in healthy behaviors during pregnancy, little is known about which factors impact these behaviors among pregnant women in Mexico. This study explored perspectives on factors impacting healthy dietary behaviors and PA in pregnancy from pregnant women and health care professionals in Mexico. We conducted semistructured interviews with 11 pregnant women and 12 health care professionals working in prenatal care. Data were analyzed using qualitative content analysis in a stepwise inductive approach. Classifying factors at the 1) individual level, 2) relational level, and 3) health care system level, three overall themes emerged. At the individual level, challenges with lack of time and competing priorities as well as knowledge of healthy dietary behaviors and PA were identified. At the relational level, influencing factors encompassed financial, social, and emotional support along with descriptive norms. At the health care system level, guidelines for PA during pregnancy and the quality of care were noted. This study identified factors impacting healthy dietary behaviors and PA in pregnancy in Mexico. Important considerations for future interventions include addressing sociocultural norms around healthy dietary behaviors and PA in pregnancy and involving pregnant women's families, closest social networks, and health care professionals working at the prenatal care unit.

Introduction: The global prevalence of people living with overweight has tripled since 1975 and more than 40% of Danish women enter pregnancy being overweight. With the increasing rates of obesity observed in children, adolescents and adults, there is an urgent need for preventive measures. Risk factors for childhood obesity include maternal overweight or obesity before conception and excessive weight gain during pregnancy. Interventions aimed at modifying maternal lifestyle during pregnancy have demonstrated minimal positive or no impact on the health of the children. The ‘healthy lifestyle before and during pregnancy to prevent childhood obesity — the PRE-STORK trial’ aims to provide insights into the effect of a lifestyle intervention initiated before conception and continued during pregnancy in women with overweight or obesity, on neonatal adiposity in their children. Methods and analysis: In this randomised, two-arm, parallel-group, controlled trial, we will include 360 women with overweight or obesity (aged 18–40; body mass index 25–44 kg/m ² ) and their partners. The women will be randomised to receive either standard of care or a lifestyle intervention focused on preconception body weight reduction, regular physical exercise, healthy diet and support from a mentor before and during pregnancy. The primary outcome is the difference in neonatal adiposity measured in their children at birth. Children conceived during the trial will constitute a birth cohort, monitoring the effects on their health until the age of 18 years. Ethics and dissemination: The trial has been approved by the Regional Committee on Health Research Ethics in the Capital Region of Denmark (identification number H-22011403) and will be conducted in agreement with the Declaration of Helsinki. All results, whether positive, negative and inconclusive, will be disseminated at national or international scientific meetings and in peer-reviewed scientific journals. Trial registration number: ClinicalTrials.gov: NCT05578690 (October 2022).

Introduction We codesigned an intervention with a low-resourced community with the aim to investigate the effects of time-restricted eating (TRE) on changes in body weight and associated cardiometabolic outcomes in South African women living with overweight/obesity and HIV who have initiated dolutegravir (DTG)-based antiretroviral therapy (ART). Methods and analysis Women with overweight or obesity (body mass index ≥25 kg/m², no upper limit), aged 20–45 years, living with HIV and in a low-resourced community, and receiving DTG-based ART for less than 2 years will be recruited from a community healthcare centre in Khayelitsha, Cape Town (n=152). Participants will be randomised 1:1 to the TRE group (n=76) or standard of care control group (n=76) for 12 months. The TRE group will be required to restrict their eating window to ~8–10 hours/day and will receive nutritional information sessions at baseline and at 3, 6, 9 and 12 months. The primary outcome of body weight will be assessed at baseline and monthly. Cardiometabolic measures will be reported as secondary outcomes. At baseline, 6- and 12 months, an oral glucose tolerance test (to estimate insulin sensitivity and beta-cell function), questionnaires (sociodemographic, food insecurity, quality of life, social support and sleep quality) and a quantified food frequency questionnaire (total energy and macronutrient composition) will be completed. Every 3 months, appetite ratings, bioelectrical impedance (fat mass and fat-free mass), fasting venous bloods (glucose, insulin, gut hormones and systemic inflammation) and process evaluation (qualitative interviews) will be completed. Monthly monitoring will also include anthropometry and blood pressure. Ethics and dissemination The study is conducted in accordance with the Declaration of Helsinki and has been approved by the Human Research Ethics Committee of the University of Cape Town (628/2021). Verbal and written consent is required from study participants. Results of this study will be published in peer-reviewed journals and presented at conferences. Trial registration number PACTR202302484999720.

Adhering to dietary recommendations after gestational diabetes mellitus (GDM) can mitigate the risk of early-onset type 2 diabetes. Psychosocial aspects, such as health literacy and perceived stress, may affect adherence to these recommendations; yet this remains underexplored in women with recent GDM. This study aimed to examine the association between health literacy and dietary quality 10-14 weeks postpartum and to assess the influence of perceived stress. Cross-sectional study. This study used baseline data from the Face-it trial, including 283 Danish women with recent GDM 10-14 weeks postpartum. Dietary quality was measured using the Dietary Quality Score (DQS), health literacy using two domains of the Health Literacy Questionnaire: HLQ-2 (Having sufficient information to manage my health) and HLQ-3 (Actively managing my health), and stress using the Perceived Stress Scale (PSS). Multiple linear regression examined the association between HLQ-2 and DQS, and HLQ-3 and DQS, adjusting for age, education, and country of birth. Additional analyses examined the influence of perceived stress. Among women with recent GDM, reporting Having sufficient information to manage their health (HLQ-2) and Actively managing their health (HLQ-3) were positively associated with dietary quality, with βadjusted = 0.55 [95 % CI: 0.22-0.87] and βadjusted = 1.12 [95 % CI: 0.84-1.41], respectively. Perceived stress did not affect these associations. Health literacy was positively associated with dietary quality among Danish women with recent GDM. Stress did not affect this association.