Chitosan derived from chitin has gathered much interest as a biopolymer due to its known and possible broad applications. Chitin is a nitrogen-enriched polymer abundantly present in the exoskeletons of arthropods, cell walls of fungi, green algae, and microorganisms, radulae and beaks of molluscs and cephalopods, etc. Chitosan is a promising candidate for a wide variety of applications due to its macromolecular structure and its unique biological and physiological properties, including solubility, biocompatibility, biodegradability, and reactivity. Chitosan and its derivatives have been known to be applicable in medicine, pharmaceuticals, food, cosmetics, agriculture, the textile and paper industries, the energy industry, and industrial sustainability. More specifically, their use in drug delivery, dentistry, ophthalmology, wound dressing, cell encapsulation, bioimaging, tissue engineering, food packaging, gelling and coating, food additives and preservatives, active biopolymeric nanofilms, nutraceuticals, skin and hair care, preventing abiotic stress in flora, increasing water availability in plants, controlled release fertilizers, dye-sensitised solar cells, wastewater and sludge treatment, and metal extraction. The merits and demerits associated with the use of chitosan derivatives in the above applications are elucidated, and finally, the key challenges and future perspectives are discussed in detail.

Polyethyleneglycol-coated biocompatible CuO–ZnO nanocomposites were fabricated hydrothermally varying Zn:Cu ratios as 1:1, 2:1, and 1:2, and their antibacterial activity was determined through the well diffusion method against the Gram-negative Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae, and the Gram-positive Staphylococcus aureus. The minimum inhibitory concentration and the minimum bactericidal concentration values of the synthesized samples were determined. Subsequently, the time synergy kill assay was performed to elucidate the nature of the overall inhibitory effect against the aforementioned bacterial species. The mean zone of inhibition values for all four samples are presented. The inhibitory effect increased with increasing concentration of the nanocomposite (20, 40 and 60 mg/ml) on all the bacterial species except for S. aureus. According to the MBC/MIC ratio, ZnO was found to be bacteriostatic for E. coli and P. aeruginosa, and bactericidal for S. aureus and K. pneumoniae. Zn:Cu 2:1 was bactericidal on all bacterial species. A bacteriostatic effect was observed on E. coli and P. aeruginosa in the presence of Zn:Cu 1:1 whereas, it showed a bactericidal effect on S. aureus and K. pneumoniae. Zn:Cu 1:2 exhibited a bacteriostatic effect on E. coli while a bactericidal effect was observed for E. coli, P. aeruginosa, and K. pneumoniae. The metal oxide nanocomposites were found to be more sensitive towards the Gram-positive strain than the Gram-negative strains. Further, all the nanocomposites possess anti-oxidant activity as shown by the DPPH assay.

High-purity (98.8%, TiO₂) rutile nanoparticles were successfully synthesized using ilmenite sand as the initial titanium source. This novel synthesis method was cost-effective and straightforward due to the absence of the traditional gravity, magnetic, electrostatic separation, ball milling, and smelting processes. Synthesized TiO₂ nanoparticles were 99% pure. Also, highly corrosive environmentally hazardous acid leachate generated during the leaching process of ilmenite sand was effectively converted into a highly efficient visible light active photocatalyst. The prepared photocatalyst system consists of anatase-TiO₂/rutile-TiO₂/Fe₂O₃ (TF-800), rutile-TiO₂/Fe₂TiO₅ (TFTO-800), and anatase-TiO₂/Fe₃O₄ (TF-450) nanocomposites, respectively. The pseudo-second-order adsorption rate of the TF-800 ternary nanocomposite was 0.126 g mg^-1 min^-1 in dark conditions, and a 0.044 min^-1 visible light initial photodegradation rate was exhibited. The TFTO-800 binary nanocomposite adsorbed methylene blue (MB) following pseudo-second-order adsorption (0.224 g mg^-1 min^-1) in the dark, and the rate constant for photodegradation of MB in visible light was 0.006 min^-1. The prepared TF-450 nanocomposite did not display excellent adsorptive and photocatalytic performances throughout the experiment period. The synthesized TF-800 and TFTO-800 were able to degrade 93.1 and 49.8% of a 100 mL, 10 ppm MB dye solution within 180 min, respectively.