Atopic dermatitis (AD) is a long-lasting inflammatory dermatological condition characterized by itchy, eczematous, sparsely tiny blisters that hold a clear watery substance. Additionally, the diseased skin can suppurate, occasionally with weeping with thickening of the affected skin. This is considered one of the top skin disorders involving both children and adult populations globally. The principal therapeutic intervention for AD is long-standing topical glucocorticoids, which have been used for several decades. Corticosteroid therapy brings several adverse drug effects (ADRs), including irreversible skin atrophy. Tacrolimus belongs to the class of calcineurin inhibitors, which is a type of immunomodulator possessing promising efficacy in treating AD. Topical tacrolimus is an effective and safe non-corticosteroid substitute treatment for AD. We reviewed the available literature to compare and institute the safety, efficacy, and effectiveness of tacrolimus when equated to corticosteroid therapy in managing AD.

Medical education has gone through tremendous evolution over the last few centuries. In the pre-Flexner and Osler era, medical education was mainly an apprenticeship-based model. After Flexner’s report in 1910, medical schools were more formalized in the West and became affiliated with universities. They ran four-year undergraduate courses comprising 2 years in preclinical basic science and two years in the clinical phase. Many other countries followed the British model, with five years of undergraduate training and one year of intensive internship training in the hospital. These knowledge-laden, didactic, teacher-centered courses could not produce skilled physicians to meet the challenges and health care needs of the 21st century. That is why innovative teaching methodologies were introduced in medical schools. Problembased learning, team-based learning, flipped classrooms, and integrated curriculum concepts were introduced. In Bangladesh, the medical education also going through a similar transition and heading towards an integrated medical curriculum. Pharmacology being a core preclinical science, is, in fact, at the cusps of clinical education. To produce competent physicians with good prescribing competency, knowledge of drugs is essential. In this perspective, pharmacology is a unique subject that should be integrated across all phases of medical education. Bangladesh Journal of Medical Science Vol. 21 No. 02 April’22 Page : 249-261

This study was done to find the pattern of drug abuse and its associated factors among the patients admitted in addiction rehabilitation centers. This descriptive cross sectional study was conducted among 150 drug addicted patients at the central drug addiction cure center at Tejgaon, Dhaka. Data were collected with a pre tested structured questionnaire. The study was conducted under the department of community medicine, National Institute of Preventive and Social Medicine (NIPSOM), Mohakhali, Dhaka during March to May 2008. Among the 150 respondents, males constituted 87%, females 12.7%. Most of the respondents (49.3%) were in the age group twenty five to thirty five years. Ninety two percent (92%) of respondents were Muslims, 78.62% urban dwellers, 14.0% from rural areas and 7.33% came from nearby slums. Literacy rate of drug abusers was 81.3%. 33.3% were unemployed, mean family monthly income was ten thousand taka. Drug of initiation was ganja/cannabis in 48.0% and finally addicted to heroin. Inhalation was the route of choice (56.6%), oral route 30.9% and intravenous drug users (IDU's) 12.5% were remarkable. Peer pressure was a major contributing factor 55.5% for drug initiation. Black market (illegal spot) 77.3% was mainly the source of procurement of drug. Mean duration of drug intake was 4.2 years. Significant association was found between male sex and drug intake (p<0.05), and between age group 25-35 years and drug intake (P< 0.05). Drug dependence is highly prevalent among educated people. Familial confliction and peer pressure lead to different drug abuse. DOI: http://dx.doi.org/10.3329/fmcj.v8i2.20371 Faridpur Med. Coll. J. 2013;8(2): 63-66

Background The outbreak of COVID-19 has remained a massive challenge for healthcare workers specially physicians. Effective professional training has a crucial role in preparing doctors for responding to pandemics. Objective To assess the effectiveness of existing training modules on enhancing knowledge, ensuring safe practice, and improving behavior on COVID-19 among physicians. Methods This is a descriptive, cross-sectional, online survey; where a virtual questionnaire was used to collect data through online professional platforms. A pre-tested survey tool was employed to assess the impact of professional training on infection prevention and control. Results Total 161 physicians participated in this survey from 15 different countries. Most of the respondents (72%) received training from various sources like the workplace (60%) and international agencies (21%), through the in-person or online format. Knowledge assessment revealed advanced (43%) and competent (40%) understanding by the participants. Improving knowledge progression was displayed by the cohort who received professional training (p<0.00). Physicians’ positive behavior and good practices were observed with the training modules. Conclusion It became evident from this study, that professional training is effective in enhancing knowledge, improving behavior, and ensuring safe practices. Hence, designing such training modules for the physicians is warranted to tackle ongoing and future pandemics.

Using medications in patient care is a cornerstone of modern therapies, which brings with it the risk of unwanted medication-related harm or adverse effects (AEs) to drugs [1,2], and not having a causal relationship with the treatment [3].

Sodium-glucose cotransporter 2 (SGLT2) inhibitors, widely used in the treatment of type 2 diabetes, have recently emerged as potential anticancer agents due to their effects on tumor metabolism and growth signaling pathways. This article presents a viewpoint on the growing body of preclinical evidence linking SGLT2 inhibition to antitumor activity, including reduced glucose uptake, AMPK activation, mTOR suppression, and cell cycle arrest. Agents such as canagliflozin, dapagliflozin, and empagliflozin have demonstrated efficacy across various cancer models, though clinical validation remains limited. We propose that SGLT2 inhibitors may offer a promising therapeutic strategy in metabolically active tumors, especially when guided by molecular profiling. While further research is needed, these findings support reconsidering the oncologic relevance of this drug class within a personalized medicine framework.