The “sol–gel method” was used to prepare spherical chitosan-modified bentonite (SCB) hydrogels in this study. The SCB hydrogels were characterized and used as sorbents to remove tetracycline (TC) from aqueous solutions. The adsorbents were characterized by SEM, XRD, FTIR, TG, and BET techniques. Various characterization results showed that the SCB adsorbent had fewer surface pores and a specific surface area that was 96.6% lower than the powder, but the layered mesoporous structure of bentonite remained unchanged. The adsorption process fit to both the Freundlich model and the pseudo-second-order kinetic model showed that it was a non-monolayer chemical adsorption process affected by intra-particle diffusion. The maximum monolayer adsorption capacity determined by the Langmuir model was 39.49 mg/g. Thermodynamic parameters indicated that adsorption was a spontaneous, endothermic, and entropy-increasing process. In addition, solid–liquid separation was easy with the SCB adsorbent, providing important reference information for the synthesis of SCB as a novel and promising adsorbent for the removal of antibiotics from wastewater at the industrial level.

In northwest China, the limited amount of water resources are classified mostly as brackish water. Nanofiltration is a widely applied desalination technology used for brackish water treatment; however, membrane fouling restricts its application. Herein, we modified the membrane with triethanolamine (TEOA) and optimized the operating conditions (transmembrane pressure, temperature, and crossflow velocity) to control the nanofiltration membrane fouling by brackish water. Based on the physiochemical characteristics and desalination performance of the prepared membranes, the membrane modified with 2% TEOA (MPCM2) was identified as the optimal membrane, and 0.5 MPa, 25 °C, and 7 cm/s were identified as the optimal operating conditions through a series of nanofiltration experiments. Moreover, the membrane cleaning procedure for fouled MPCM2 was further determined, and a two-step cleaning procedure using ethylene diamine tetraacetic acid disodium followed by HCl with a permeance recovery rate of 98.77% was identified as the optimal cleaning procedure. Furthermore, the characterizations of the fouled and cleaned MPCM2 showed that the optimized cleaning procedure could recover the properties of MPCM2 to near virgin. This study is of great significance for the long-term stable operation of nanofiltration processes in brackish water treatment to ensure the supply of healthy water in the water-deficient areas of northwest China.