Manuel Murbach

Dr. Manuel Murbach


Research Focus & Metrics

Academic Career Length

15Years (2012-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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14 February 2013 in Magnetic Resonance in Medicine
Verified
Journal Article
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MMManuel Murbach
Manuel Murbach
ENEsra Neufeld
Esra Neufeld
MCMyles Capstick
Myles Capstick
WKWolfgang Kainz
Wolfgang Kainz
DBDavid O. Brunner
David O. Brunner
NKNiels Kuster
Niels Kuster
Purpose: This article investigates the safety of radiofrequency induced local thermal hotspots within a 1.5T body coil by assessing the transient local peak temperatures as a function of exposure level and local thermoregulation in four anatomical human models in different Z‐positions.Methods: To quantize the effective thermal stress of the tissues, the thermal dose model cumulative equivalent minutes at 43°C was employed, allowing the prediction of thermal tissue damage risk and the identification of potentially hazardous MR scan‐scenarios. The numerical results were validated by B1+− and skin temperature measurements.Results: At continuous 4 W/kg whole‐body exposure, peak tissue temperatures of up to 42.8°C were computed for the thermoregulated model (60°C in nonregulated case). When applying cumulative equivalent minutes at 43°C damage thresholds of 15 min (muscle, skin, fat, and bone) and 2 min (other), possible tissue damage cannot be excluded after 25 min for the thermoregulated model (4 min in nonregulated).Conclusion: The results are found to be consistent with the history of safe use in MR scanning, but not with current safety guidelines. For future safety concepts, we suggest to use thermal dose models instead of temperatures or SAR. Special safety concerns for patients with impaired thermoregulation (e.g., the elderly, diabetics) should be addressed. Magn Reson Med 71:421–431, 2014. © 2013 Wiley Periodicals, Inc.

13 May 2016 in Magnetic Resonance in Medicine
Verified
Journal Article
Closed access
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MMManuel Murbach
Manuel Murbach
ENEsra Neufeld
Esra Neufeld
Theodoros SamarasTheodoros Samaras
Theodoros Samaras
Juan CórcolesJuan Córcoles
Juan Córcoles
FRFraser J. Robb
Fraser J. Robb
NKNiels Kuster
Niels Kuster

24 September 2015 in Magnetic Resonance in Medicine
Verified
Journal Article
Open access
PDF file
MMManuel Murbach
Manuel Murbach
ENEsra Neufeld
Esra Neufeld
ECEugenia Cabot
Eugenia Cabot
EZEarl Zastrow
Earl Zastrow
Juan CórcolesJuan Córcoles
Juan Córcoles
NKNiels Kuster
Niels Kuster
Purpose: To assess the effect of radiofrequency (RF) shimming of a 3 Tesla (T) two‐port body coil on B1+ uniformity, the local specific absorption rate (SAR), and the local temperature increase as a function of the thermoregulatory response.Methods: RF shimming alters induced current distribution, which may result in large changes in the level and location of absorbed RF energy. We investigated this effect with six anatomical human models from the Virtual Population in 10 imaging landmarks and four RF coils. Three thermoregulation models were applied to estimate potential local temperature increases, including a newly proposed model for impaired thermoregulation.Results: Two‐port RF shimming, compared to circular polarization mode, can increase the B1+ uniformity on average by +32%. Worst‐case SAR excitations increase the local RF power deposition on average by +39%. In the first level controlled operating mode, induced peak temperatures reach 42.5°C and 45.6°C in patients with normal and impaired thermoregulation, respectively.Conclusion: Image quality with 3T body coils can be significantly increased by RF shimming. Exposure in realistic scan scenarios within guideline limits can be considered safe for a broad patient population with normal thermoregulation. Patients with impaired thermoregulation should not be scanned outside of the normal operating mode. Magn Reson Med 76:986–997, 2016.

13 February 2012 in Bioelectromagnetics
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Journal Article
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MMManuel Murbach
Manuel Murbach
MCMaria Christopoulou
Maria Christopoulou
PCPedro Crespo‐Valero
Pedro Crespo‐Valero
PAPeter Achermann
Peter Achermann
NKNiels Kuster
Niels Kuster

1 January 2014 in BMC Veterinary Research
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Journal Article
Open access
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MHMichael Robert Hässig
Michael Robert Hässig
MWMarietta Wullschleger
Marietta Wullschleger
HNHanspeter Naegeli
Hanspeter Naegeli
JKJaqueline Kupper
Jaqueline Kupper
BSBernhard Spiess
Bernhard Spiess
MMManuel Murbach
Manuel Murbach
The influence of electromagnetic fields on the health of humans and animals is still an intensively discussed and scientifically investigated issue (Prakt Tierarzt 11:15-20, 2003; Umwelt Medizin Gesellschaft 17:326-332, 2004; J Toxicol Environment Health, Part B 12:572–597, 2009). We are surrounded by numerous electromagnetic fields of variable strength, coming from electronic equipment and its power cords, from high-voltage power lines and from antennas for radio, television and mobile communication. Particularly the latter cause’s controversy, as everyone likes to have good mobile reception at anytime and anywhere, whereas nobody wants to have such a basestation antenna in their proximity.