Johannes Kahn

Dr. Johannes Kahn

Department of Neuroradiology, Charité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Augustenburger Platz 1, 13353 Berlin, Germany

Research Focus & Metrics

Academic Career Length

14Years (2013-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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6 April 2015 in Acta Radiologica
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Journal Article
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JKJohannes Kahn
Johannes Kahn
UGUlrich Grupp
Ulrich Grupp
DKDavid Kaul
David Kaul
GBGeorg Böning
Georg Böning
TLTobias Lindner
Tobias Lindner
FSFlorian Streitparth
Florian Streitparth
Background: Rising numbers of computed tomography (CT) examinations worldwide have led to a focus on dose reduction in the latest developments in CT technology. Iterative reconstruction (IR) models bear the potential to effectively reduce dose while maintaining adequate image quality. Purpose: To assess the impact of adaptive statistical iterative reconstruction (ASIR) technique on dose reduction and image quality in a dedicated whole body CT (WBCT) protocol for trauma patients. Material and Methods: A total of 122 subjects with multiple trauma was prospectively included in our study. Subjects who had to undergo a WBCT following a severe trauma were randomly assigned to two different groups: Group A was examined with an ASIR protocol for the body series ( n = 64), group B ( n = 58) was examined using a standard filtered back projection (FBP) protocol. Image quality was assessed both quantitatively by calculating signal-to-noise ratio (SNR) and contrast-to-noise ratios (CNRs) and qualitatively by two observers who evaluated image quality using a 5-point scale system. Applied dose was analyzed as CTDIvol (mGy), total DLP (mGyxcm), and effective dose (mSv). Results: Applied dose for the body series in group A was about 23% lower than in group B ( P < 0.05). SNR and CNRs for different tissues were not significantly different. Subjective image quality ratings were excellent and showed no significant difference, with a high inter-reader agreement. Conclusion: ASIR contributes to a relevant dose reduction without any loss of image quality in a dedicated WBCT protocol for patients with multiple trauma.


1 February 2021 in European Journal of Radiology
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Journal Article
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JVJan Oliver Voss
Jan Oliver Voss
CDChristian Doll
Christian Doll
JRJan D. Raguse
Jan D. Raguse
BBBenedicta Beck-Broichsitter
Benedicta Beck-Broichsitter
TWThula Cannon Walter-Rittel
Thula Cannon Walter-Rittel
NTNadine Thieme
Nadine Thieme

10 July 2014 in European Radiology
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DKDavid Kaul
David Kaul
UGUlrich Grupp
Ulrich Grupp
JKJohannes Kahn
Johannes Kahn
Pirus GhadjarPirus Ghadjar
Pirus Ghadjar
EWEdzard Wiener
Edzard Wiener
FSFlorian Streitparth
Florian Streitparth


26 June 2017 in RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren
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Journal Article
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JKJohannes Kahn
Johannes Kahn
DKDavid Kaul
David Kaul
GBGeorg Böning
Georg Böning
RRRoman Rotzinger
Roman Rotzinger
PFPatrick Freyhardt
Patrick Freyhardt
FSFlorian Streitparth
Florian Streitparth
Purpose As a supra-regional level-I trauma center, we evaluated computed tomography (CT) acquisitions of polytraumatized patients for quality and dose optimization purposes. Adapted statistical iterative reconstruction [(AS)IR] levels, tube voltage reduction as well as a split-bolus contrast agent (CA) protocol were applied. Materials and Methods 61 patients were split into 3 different groups that differed with respect to tube voltage (120 – 140 kVp) and level of applied ASIR reconstruction (ASIR 20 – 50 %). The CT protocol included a native acquisition of the head followed by a single contrast-enhanced acquisition of the whole body (64-MSCT). CA (350 mg/ml iodine) was administered as a split bolus injection of 100 ml (2 ml/s), 20 ml NaCl (1 ml/s), 60 ml (4 ml/s), 40 ml NaCl (4 ml/s) with a scan delay of 85 s to detect injuries of both the arterial system and parenchymal organs in a single acquisition. Both the quantitative (SNR/CNR) and qualitative (5-point Likert scale) image quality was evaluated in parenchymal organs that are often injured in trauma patients. Radiation exposure was assessed. Results The use of IR combined with a reduction of tube voltage resulted in good qualitative and quantitative image quality and a significant reduction in radiation exposure of more than 40 % (DLP 1087 vs. 647 mGyxcm). Image quality could be improved due to a dedicated protocol that included different levels of IR adapted to different slice thicknesses, kernels and the examined area for the evaluation of head, lung, body and bone injury patterns. In synopsis of our results, we recommend the implementation of a polytrauma protocol with a tube voltage of 120 kVp and the following IR levels: cCT 5mm: ASIR 20; cCT 0.625 mm: ASIR 40; lung 2.5 mm: ASIR 30, body 5 mm: ASIR 40; body 1.25 mm: ASIR 50; body 0.625 mm: ASIR 0. Conclusion A dedicated adaptation of the CT trauma protocol (level of reduction of tube voltage and of IR) according to the examined body region (head, lung, body, bone) combined with a split bolus CA injection protocol allows for a high-quality CT examination and a relevant reduction of radiation exposure in the examination of polytraumatized patients Key Points Citation Format