Agriculture is facing challenges such as water scarcity, low fertilizer utilization, food security and environmental sustainability. Therefore, the development of slow-release fertilizer (SRF) with controlled water retention and release is particularly important. Slow-release fertilizer hydrogel (SRFH) has a three-dimensional (3D) network structure combined with fertilizer processing, displaying excellent hydrophilicity, biocompatibility and controllability. Cellulose has abundant hydroxyl groups as well as outstanding biodegradability and special mechanical properties, which make it a potential candidate material for the fabrication of hydrogels. This work would analyze and discuss various methods for preparing stimulus-responsive cellulose hydrogels and their combinations with different fertilizers. Moreover, the application and release mechanism of stimulus-responsive cellulose hydrogels in SRF have been summarized as well. Finally, we would explore the potential issues of stimulus-responsive cellulose hydrogels serving as an SRF, propose reasonable solutions and give an outlook of the future research directions.