Elisa Pesce is a Postdoc Researcher at the National Institute of Molecular Genetics (INGM), Milano. She is a highly skilled senior scientist with an extensive background in protein synthesis control (more than 10 years) and immunology. She is working in the Translational Research Unit at INGM, where in the last two years she contributed to many projects based on COVID-19. In particular, she led a study to characterize the role of exosomes upon viral infection, both at the immunological and proteomic level. During her postdoc, she developed a platform named iRIA (in vitro Ribosomes Interaction Assay) to study protein–protein interaction between the ribosomal surface and recombinant proteins. With the iRIA, she performed an automated screening of synthetic drugs, and she discovered three compounds with a biological activity that can modulate the binding of eIF6 to the 60S and then translation. This study represents an important starting point for future studies addressing the possibility of pharmacologically inhibiting the activity of eIF6.