Rienk Rienks

Dr. Rienk Rienks

orcid

Research Focus & Metrics

Academic Career Length

5Years (2022-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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23 June 2025 in BMJ Open
Verified
Journal Article
Open access
EFErik Frijters
Erik Frijters
HNHendrik Nathoe
Hendrik Nathoe
RGRemco Grobben
Remco Grobben
LBLysette Broekhuizen
Lysette Broekhuizen
RRRienk Rienks
Rienk Rienks
BVBirgitta Velthuis
Birgitta Velthuis
Objective: Coronary artery disease (CAD) is a main cause of incapacitating adverse cardiac events in aviation. Military aircrew ≥40 years in the Netherlands undergo a 5-year exercise ECG (X-ECG), which lacks precision to identify relevant CAD. The study aim was to identify the screening value of cardiac CT (CCT) in asymptomatic military aircrew. Design: Prospective, single-centre, cross-sectional study. Setting: Conducted at the Centre for Man in Aviation, Royal Netherlands Air Force. CT scans were performed at the University Medical Centre, Utrecht. Participants: Asymptomatic military aircrew ≥40 years were asked to undergo CCT, with coronary artery calcium score (CACS) and coronary CT angiography (CCTA), following their aeromedical exam. CCT was performed in 211 participants (median age 49.3 years (43.6–52.8), 98% men, 65% pilots). Outcome measures: The main objective was to determine the prevalence of relevant CAD. Clinically relevant CAD (CR-CAD) is defined as CACS ≥100 and/or a stenosis ≥50%. Aeromedically relevant CAD (AR-CAD) includes CR-CAD and/or a left main stenosis >30% or an aggregate stenosis ≥120%. Secondary objectives included assessing the prevalence of mild coronary stenosis (defined as 25%–49% stenosis), the presence of high-risk plaque (HRP) features and CCT safety. Results: CR-CAD was found in 25 male aircrew (12%), with a CACS of ≥100 in 21 (10%) and a stenosis ≥50% in 10 (5%), including two with CACS 0. Two additional men had ≥120% aggregate stenosis, bringing total AR-CAD to 27 (13%). Twenty-nine men (14%) had mild stenosis. HRP features were present in 44 (21%). There were no CT-related complications. Of 196 participants who underwent X-ECG, seven showed abnormal results; one had relevant CAD. Conclusions: Contrast-enhanced CCTA provides additional information both on high-risk features and obstructive CAD compared with CACS only. CCT is safe and is of additional value to X-ECG in a low-risk population with a high-hazard occupation. Trial registration number: NCT05508893.

Verified
Journal Article
Open access
PDF file
RKRobert Martijn Kauling
Robert Martijn Kauling
RRRienk Rienks
Rienk Rienks
JCJudith A. A. E. Cuypers
Judith A. A. E. Cuypers
HJHarald T. Jorstad
Harald T. Jorstad
JRJolien W. Roos-Hesselink
Jolien W. Roos-Hesselink
Conventionally, scuba diving has been discouraged for adult patients with congenital heart disease (ACHD). This restrictive sports advice is based on expert opinion in the absence of high-quality diving-specific studies. However, as survival and quality of life in congenital heart disease (CHD) patients have dramatically improved in the last decades, a critical appraisal whether such restrictive sports advice is still applicable is warranted. In this review, the cardiovascular effects of diving are described and a framework for the work-up for ACHD patients wishing to engage in scuba diving is provided. In addition, diving recommendations for specific CHD diagnostic groups are proposed.

6 May 2022 in Undersea and Hyperbaric Medicine
Verified
Journal Article
Closed access
RRRienk Rienks
Rienk Rienks
ACAmsterdam CardioExpert Clinic for Sports and Occupational Cardiology
Amsterdam CardioExpert Clinic for Sports and Occupational Cardiology
MBMattijn Buwalda
Mattijn Buwalda
OSOdijk Medical And Educational Services
Odijk Medical And Educational Services
JBJeroen Bucx
Jeroen Bucx
RHRob van Hulst
Rob van Hulst
Similar to aviation, diving is performed in an environment in which acute incapacitation may lead to a fatal outcome. In aeromedicine, a pilot is considered “unfit to fly” when the cardiovascular event risk exceeds one percent per annum, the so-called 1% rule. In diving no formal limits to cardiovascular risk have been established. Cardiovascular risk of divers can be calculated using the modified Canadian Cardiovascular Society (CCS) Risk of Harm formula: risk of harm (RH: cardiovascular fatality rate per year during diving: number × 10-5 divers/year) = time diving (TD: number of dives × 10-4) × sudden cardiac incapacitation (SCI: cardiovascular diver event rate per year (number × 10-5/year). The SCI and thus the RH are strongly dependent on age. Using the CCS criterion for RH, 5 × 10-5 divers/year, and considering an average of 25 dives per year per diver, the calculated maximum acceptable SCI is 2%/year, consistent with current practice for dive medical examinations. If the SCI were to exceed 2%/year, a diver could be considered “unfit to dive,” which could particularly benefit older (≥ 50 years) divers, in whom cardiovascular risk factors are often not properly treated. For the prevention of fatal diving accidents due to atherosclerotic cardiovascular disease, a dive medical examination is of limited value for young (<50 years) divers who have no cardiovascular risk factors. Introducing a cardiovascular risk management system for divers may achieve a reduction in fatal diving accidents that result from cardiovascular disease in older divers engaged in both recreational and professional diving.

9 August 2022 in European Journal of Clinical Investigation
Verified
Journal Article
Closed access
HJHarald T. Jørstad
Harald T. Jørstad
RRRienk Rienks
Rienk Rienks