Groundwater is a critical water supply for safe drinking water, agriculture, and industry worldwide. In the Khanewal district of Punjab, Pakistan, groundwater has severely deteriorated during the last few decades due to environmental changes and anthropogenic activities. Therefore, 68 groundwater samples were collected and analyzed for their main ions and trace elements to investigate the suitability of groundwater sources for drinking and agricultural purposes. Principal component analysis (PCA) and cluster analysis (CA) were employed to determine the major factors influencing groundwater quality. To assess the groundwater’s appropriateness for drinking and irrigation, drinking and agricultural indices were used. The pH of the groundwater samples ranged from 6.9 to 9.2, indicating that the aquifers were slightly acidic to alkaline. The major cations were distributed as follows: Na⁺ > Ca²⁺ > Mg²⁺ > K⁺. Meanwhile, the anions are distributed as follows: HCO₃⁻ > SO₄²⁻ > Cl⁻ > F⁻. The main hydrochemical facies were identified as a mixed type; however, a mixed magnesium, calcium, and chloride pattern was observed. The reverse ion exchange process helps in exchanging Na⁺ with Ca²⁺ and Mg²⁺ ions in the groundwater system. Rock weathering processes, such as the dissolution of calcite, dolomite, and gypsum minerals, dominated the groundwater hydrochemistry. According to the Weight Arithmetic Water Quality Index (WAWQI), 50% of the water samples were unsafe for drinking. The Wilcox diagram, USSL diagram, and some other agricultural indices resulted in around 32% of the groundwater samples being unsuitable for irrigation purposes. The Khanewal’s groundwater quality was vulnerable due to geology and the influence of anthropogenic activities. For groundwater sustainability in Khanewal, management strategies and policies are required.

HKUST-1 is a copper-based metal–organic framework (MOF). The HKUST-1/PMS/Vis system can effectively degrade RhB and MB but accomplish poor removal of AO ₇ and MR, which is attributed to the repulsion between surface charges.