David A. Martínez

Dr. David A. Martínez

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Research Focus & Metrics

Academic Career Length

5Years (2022-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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29 December 2022 in Veterinary Sciences
Verified
Journal Article
Open access
PDF file
DMDavid A. Martínez
David A. Martínez
MCManuel F. Chamorro
Manuel F. Chamorro
TPThomas Passler
Thomas Passler
LHLaura Huber
Laura Huber
PWPaul H. Walz
Paul H. Walz
AWAmelia R. Woolums
Amelia R. Woolums
Maternal antibodies interfere with BRSV vaccine responses and efficacy in young calves. The objective of this study was to determine if vaccination before the complete absorption of colostral antibodies results in adequate immune priming and clinical protection of beef calves. Within 6 h of life, calves were randomly assigned to 2 different treatment groups. Group Vacc (n = 25) received a single dose of a modified-live virus (MLV) BRSV vaccine intranasally (IN) and group Control (n = 25) received 2 mL of 0.9% saline IN. At approximately 3 months of age, all calves were experimentally challenged with BRSV. Serum and nasal secretion samples were collected before and after challenge for BRSV real-time RT-PCR and antibody testing. Respiratory signs were not observed before challenge. After challenge, respiratory scores were similar between groups. On the challenge day, >40% of calves in each group were febrile. The mean serum and nasal BRSV-specific antibody titers indicated natural BRSV exposure before the experimental challenge in both groups. All calves tested positive for BRSV and had a similar duration of shedding after challenge. Based on these results, vaccination at birth does not offer advantages for immune priming or clinical protection for beef calves in BRSV-endemic cow-calf herds.

25 June 2022 in Veterinary Record Case Reports
Verified
Journal Article
Closed access
JYJi-Hang Yin
Ji-Hang Yin
DMDavid A. Martínez
David A. Martínez
MCManuel F. Chamorro
Manuel F. Chamorro
Sandra Leanne DillardSandra Leanne Dillard
Sandra Leanne Dillard
RCRussell Cattley
Russell Cattley

22 June 2023 in Revista de Medicina Veterinaria
Verified
Journal Article
Open access
PDF file
CMClaudia María Daza Medina
Claudia María Daza Medina
MAMartha Susana Franco Ayala
Martha Susana Franco Ayala
DMDavid A. Martínez
David A. Martínez
Los potros neonatos son susceptibles a enfermedades potencialmente mortales. Por tanto, es importante identificar marcadores que permitan predecir la supervivencia de estos pacientes, e iniciar el tratamiento adecuado para cada caso. Este estudio fue realizado en el Centro de Perinatología Equina Foal Care ubicado en Cajicá, Cundinamarca. Se revisaron y analizaron las historias clínicas de 106 potros que ingresaron a hospitalización entre septiembre de 2019 y diciembre de 2020 para evaluar el valor predictivo de los parámetros de gases sanguíneos y electrolitos frente a la supervivencia de potros neonatos hospitalizados. Se utilizaron diferentes pruebas estadísticas como la prueba de Kolmogorov Smirnov, U de Mann-Whitney, regresión logística binaria, pruebas de chi cuadrado, odds ratio y análisis de la curva de características del operador del receptor (ROC). Se observó que el desorden ácido-básico más común al ingreso a hospitalización fue la acidosis metabólica (37/106), y el desequilibrio electrolítico más frecuente fue la hipocalcemia (89/106). La variable más significativamente relacionada con la supervivencia fue el pH > 7,35 (p = ,007; OR = 0,288; IC = 95 %, 0,117-0,706). Los factores de riesgo asociados con la no supervivencia de los potros fueron pH < 7,35, lactato > 4,5 y glucosa < 119,5 mg/dl.