Imen Belhadj Slimen

Dr. Imen Belhadj Slimen

orcid

Research Focus & Metrics

Academic Career Length

13Years (2014-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
17 October 2014 in International Journal of Hyperthermia
Verified
Journal Article
Closed access
ISImen Belhadj Slimen
Imen Belhadj Slimen
TNTaha Najar
Taha Najar
AGAbdeljelil Ghram
Abdeljelil Ghram
HDHajer Dabbebi
Hajer Dabbebi
MMMoncef Ben Mrad
Moncef Ben Mrad
MAManef Abdrabbah
Manef Abdrabbah
In recent years there has been enormous interest in researching oxidative stress. Reactive oxygen species (ROS) are derived from the metabolism of oxygen as by-products of cell respiration, and are continuously produced in all aerobic organisms. Oxidative stress occurs as a consequence of an imbalance between ROS production and the available antioxidant defence against them. Nowadays, a variety of diseases and degenerative processes such as cancer, Alzheimer's and autoimmune diseases are mediated by oxidative stress. Heat stress was suggested to be an environmental factor responsible for stimulating ROS production because of similarities in responses observed following heat stress compared with that occurring following exposure to oxidative stress. This manuscript describes the main mitochondrial sources of ROS and the antioxidant defences involved to prevent oxidative damage in all the mitochondrial compartments. It also deals with discussions concerning the cytotoxic effect of heat stress, mitochondrial heat-induced alterations, as well as heat shock protein (HSP) expression as a defence mechanism.

6 August 2015 in Journal of Animal Physiology and Animal Nutrition
Verified
Journal Article
Closed access
PDF file
ISImen Belhadj Slimen
Imen Belhadj Slimen
TNT. Najar
T. Najar
AGA. Ghram
A. Ghram
MAM. Abdrrabba
M. Abdrrabba

18 January 2017 in Journal of Agricultural and Food Chemistry
Verified
Journal Article
Closed access
ISImen Belhadj Slimen
Imen Belhadj Slimen
TNTaha Najar
Taha Najar
MAManef Abderrabba
Manef Abderrabba

1 January 2017 in Cell Biology
Verified
Journal Article
Open access
PDF file
ISImen Belhadj Slimen
Imen Belhadj Slimen
MMMahmoud Mabrouk
Mahmoud Mabrouk
CHChaabane Hanène
Chaabane Hanène
TNTaha Najar
Taha Najar
MAManef Abderrabba
Manef Abderrabba
Opuntia ficus-indica belongs to the Cactaceae family and is widespread in semi-arid and arid regions. Cactus pears are known for their health promoting properties which are due to a variety of bioactive molecules. This study aims to identify and quantify phenolic acids, flavonoids and betanin from spineless Opuntia ficus-indica fruits. Fresh mature samples were crushed, and extracted with 50% aqueous ethanol. The identification process was carried out using a Shimadzu high performance liquid chromagraph equipped with a quadrupole mass spectrum. Quantification was made using calibration curves of analytical standards. 9 phenolic acids, 1 flavan-3-ol, 2 flavanones, 3 flavonols, 6 flavones and 2 betacyanins were identified. Important levels of betanin, quinic acid, cirsiliol, acacetin, transcinnamic acid, rutin and naringin were calculated. Our results indicated that Opuntia ficus-indica fruits are an important dietary source of phenolic compounds and betalains with high antioxidant capacity.

10 April 2023 in Molecules
Verified
Journal Article
Open access
PDF file
BKBochra Bejaoui Kefi
Bochra Bejaoui Kefi
CSChaima Sdiri
Chaima Sdiri
IBIkram Bensouf
Ikram Bensouf
ISImen Belhadj Slimen
Imen Belhadj Slimen
MLManel Ben Larbi
Manel Ben Larbi
Naceur M'HamdiNaceur M'Hamdi
Naceur M'Hamdi
Heat stress is one of the most stressful events in livestock life, negatively impacting animal health, productivity, and product quality. Moreover, the negative impact of heat stress on animal product quality has recently attracted increasing public awareness and concern. The purpose of this review is to discuss the effects of heat stress on the quality and the physicochemical component of meat in ruminants, pigs, rabbits, and poultry. Based on PRISMA guidelines, research articles were identified, screened, and summarized based on inclusion criteria for heat stress on meat safety and quality. Data were obtained from the Web of Science. Many studies reported the increased incidences of heat stress on animal welfare and meat quality. Although heat stress impacts can be variable depending on the severity and duration, the exposure of animals to heat stress (HS) can affect meat quality. Recent studies have shown that HS not only causes physiological and metabolic disturbances in living animals but also alters the rate and extent of glycolysis in postmortem muscles, resulting in changes in pH values that affect carcasses and meat. It has been shown to have a plausible effect on quality and antioxidant activity. Acute heat stress just before slaughter stimulates muscle glycogenolysis and can result in pale, tender, and exudative (PSE) meat characterized by low water-holding capacity (WHC). The enzymatic antioxidants such as superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) act by scavenging both intracellular and extracellular superoxide radicals and preventing the lipid peroxidation of the plasma membrane. Therefore, understanding and controlling environmental conditions is crucial to successful animal production and product safety. The objective of this review was to investigate the effects of HS on meat quality and antioxidant status.

1 January 2016 in Journal of Food and Nutrition Sciences
Verified
Journal Article
Open access
PDF file
ISImen Belhadj Slimen
Imen Belhadj Slimen
TNTaha Najar
Taha Najar
MAManef Abderrabba
Manef Abderrabba
Cacti are known for their minimum water requirement. They grow extensively in arid lands, where they were traditionally used for both human and animal food. Opuntia ficus-indica, commonly referred to as prickly pear or nopal cactus, was known as a medicinal plant, owing to its rich composition in polyphenols, vitamins, polyunsaturated fatty acids and amino acids. This makes cactus pear a promising crop for commercial food applications. Recent scientific investigations showed thatcactus products may be efficiently used as a source of foods additives, mainly fibre, colorants and antioxidants. Tablets, cookies and other forms of fibre derived from cactus cladodes are currently marketed in severalAmerican countries. This review details the main functional phytochemicals characterizing different tissues of Opuntia ficus-indica.