Skin, mental health and the central nervous system (CNS) are connected by a deep link. It is not only the aesthetic and sometimes the disfiguring aspects of dermatological conditions that can cause a severe psychological burden; also, different studies have shown how chronic skin-inflammatory diseases may influence the activity of the CNS and vice versa. Moreover, the skin and brain share a common embryogenic origin. Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease affecting the hair follicles of the apocrine regions. The main clinical features are nodules, abscesses, cysts, fistulae and disfiguring scars. Pain and stinking discharge from fistulae are often present. It is not surprising that the psychological burden associated with HS is frequently a challenge in dermatologists’ daily routines. Patients often suffer from depression and anxiety, but also from substance abuse, psychotic and bipolar disorders and an increased suicide risk. The aim of this article is to review the main psychiatric disorders associated with HS and their pathophysiology. Research on Pubmed was conducted with the key words Hidradenitis suppurativa, psychiatric, depression, anxiety, bipolar, schizophrenia, abuse, suicidal. A high incidence of psychiatric disorders has been described in HS compared to controls. Hidradenitis suppurativa is not a rare disease, and acknowledging the HS psychological burden, psychiatric-associated diseases and associated biomolecular pathways will help dermatologists to better care for their patients.

Citation: Caccavale S, Boccellino MP, Fiorentino C, Argenziano G. Pigmented Trichoepitheliomas, Not an Uncommon Variant: A Dermoscopical Insight. Dermatol Pract Concept. 2024;14(1):e2024009. DOI: https://doi.org/10.5826/dpc.1401a9 Accepted: July 30, 2023; Published: January 2024 Copyright: ©2024 Caccavale et al. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (BY-NC-4.0), https://creativecommons.org/licenses/by-nc/4.0/, which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original authors and source are credited. Funding: None. Competing interests: None. Authorship: All authors have contributed significantly to this publication. Corresponding author: Stefano Caccavale, MD, Dermatology Unit, Department of Mental and Physical Health and Preventive Medicine, University of Campania Luigi Vanvitelli, Via Sergio Pansini, 5, 80131 Naples, Italy; phone: +39 3336365526; fax: +39 0815468759; e-mail: stefano85med@libero.it Keywords : dermoscopy, pigmented trichoepithelioma, Trichoepithelioma, basal cell carcinoma This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Psoriasis is a chronic inflammatory skin disease associated with metabolic comorbid conditions, including obesity. The crosstalk between adipose | POSTER

Citation: Caccavale S, Fiorentino C, Boccellino MP, Pagliuca F, Jurakic Toncic R, Argenziano G. Multiple Pigmented Trichoepitheliomas: A Case Report. Dermatol Pract Concept. 2023;13(2):e2023128. DOI: https://doi.org/10.5826/dpc.1302a128 Accepted: November 2, 2022; Published: April 2023 Copyright: ©2023 Caccavale et al. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (BY-NC-4.0), https://creativecommons.org/licenses/by-nc/4.0/, which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original authors and source are credited. Funding: None. Competing interests: None. Authorship: All authors have contributed significantly to this publication. Corresponding author: Stefano Caccavale, MD, Dermatology Unit, Department of Mental and Physical Health and Preventive Medicine, University of Campania Luigi Vanvitelli, Via Sergio Pansini, 5, 80131 Naples, Italy; phone: +39 3336365526; fax: +39 0815468759; e-mail: stefano85med@libero.it This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.