Nanotechnological advancements over the past few years have led to the development of newer treatment strategies in brain cancer therapy which leads to the establishment of nano oncology. Nanostructures with high specificity, are best suitable to penetrate the blood–brain barrier (BBB). Their desired physicochemical properties, such as small sizes, shape, higher surface area to volume ratio, distinctive structural features, and the possibility to attach various substances on their surface transform them into potential transport carriers able to cross various cellular and tissue barriers, including the BBB. The review emphasizes nanotechnology-based treatment strategies for the exploration of brain tumors and highlights the current progress of different nanomaterials for the effective delivery of drugs for brain tumor therapy.

Background: The nanotechnology which has vast growth in the research field and the outcome product of nanotechnology is nanoparticles. Quantum dots with a size range of 2-10nm represents a new form in nanotechnology materials. It has showed widespread attention in recent years in the field of science and its application in drug delivery. Quantum dots are semiconductor nanocrystals which possess interesting properties and characteristics such as unique optical properties, quantum confinement effect and emit fluorescence on excitation with a light source which makes them a potential candidate for nano-probes and for carriers for biological application. Objective: The objective of the article is to explain the role and application of Quantum dots in drug delivery and its future application in pharmaceutical science and research. This review focuses on drug delivery through Quantum dots and Quantum dots helping nanocarriers for drug delivery. The development of QD nano-carriers for drugs has become a hotspot in the fields of nano-drug research. The Quantum Dot labelled nano-carrier can able to deliver the drugs with fewer side effects and it can able to trace the drug location in the body. Results: The Fluorescent emission of Quantum dots is better than other organic dyes which leads to better drug delivery for cancer or acting as a tag for other drug carriers. Conclusion: Because of emission property of Quantum Dots, it can be said used with other drug carriers and later it can be traced with the help of Quantum Dots. Quantum dots can be said as smart Drug delivery.

Psoriasis is a chronic autoimmune condition that is described by infected skin patches. Ultradeformable vesicles have been a novel carrier for the treatment of psoriasis in topical and transdermal ...

Praveen Halagali1, Rohan Singadi2, Hunsur Ranganath Arjun3, Gundada Sivaraj Rakshanaa3, Salini Parameswaran Nair3, Prashant Halagali4 and Preethi Somanna1 Author informationPDFCitations 1Department of Pharmaceutics, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Mysuru, Karnataka, INDIA 2Department of Pharmaceutical Chemistry, KLE College of Pharmacy, KLE Academy of Higher Education and Research, Belagavi, Karnataka, INDIA

Background Fumaria parviflora (FP) is a medicinal herb that is used in several traditional medicines to treat diseases like folliculitis, erysipelas. Fumaria parviflora Lam. belonging to the family Papaveraceae is used widely in traditional and folkloric medicine. It is known as ‘Pittapapra’ in Ayurveda, and ‘Shahtaraa’ in Unani is used to treat various ailments like indigestion, vomiting, fever, and fatigue. It is showing properties like anthelminthic, diuretic, diaphoretic, and blood-purifying properties. The present study is done to evaluate the antibacterial and antifungal properties of the extract. Materials and Methods The plant extract was isolated by using a Soxhlet apparatus by using ethanol as the solvent. The extract was filtered using filter paper and heated in the oven to obtain the plant extract concentrate. The o/w emulsion-based cream was evaluated for pH, viscosity, thermal stability, spreadability, antibacterial (S. aureus and E. coli) and antifungal (C. albicans and A. niger) activity. Results The o/w emulsion-based cream formulations were found to be stable, found to have pH compatible to human skin, no skin irritancy and also have good spreadability properties, and found to be effective against bacterial cells but no considerable effect on fungal cells. Conclusion The o/w emulsion-based cream formulations were examined for both antibacterial and antifungal activities but from the results we concluded that Fumaria parviflora Lam. is found to be effective against bacterial cells and useful in treating bacterial skin infections.