Mario Zanaty

Dr. Mario Zanaty

Department of Neurosurgery, University of Iowa Hospital and Clinics, Iowa City, IA, USA
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Research Focus & Metrics

Academic Career Length

14Years (2013-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 January 2015 in The Scientific World Journal
Verified
Journal Article
Open access
PDF file
NANorman Ajiboye
Norman Ajiboye
NCNohra Chalouhi
Nohra Chalouhi
RSRobert M Starke
Robert M Starke
MZMario Zanaty
Mario Zanaty
RBRodney Bell
Rodney Bell
The evolution of imaging techniques and their increased use in clinical practice have led to a higher detection rate of unruptured intracranial aneurysms. The diagnosis of an unruptured intracranial aneurysm is a source of significant stress to the patient because of the concerns for aneurysmal rupture, which is associated with substantial rates of morbidity and mortality. Therefore, it is important that decisions regarding optimum management are made based on the comparison of the risk of aneurysmal rupture with the risk associated with intervention. This review provides a comprehensive overview of the epidemiology, pathophysiology, natural history, clinical presentation, diagnosis, and management options for unruptured intracranial aneurysms based on the current evidence in the literature. Furthermore, the authors discuss the genetic abnormalities associated with intracranial aneurysm and current guidelines for screening in patients with a family history of intracranial aneurysms. Since there is significant controversy in the optimum management of small unruptured intracranial aneurysms, we provided a systematic approach to their management based on patient and aneurysm characteristics as well as the risks and benefits of intervention.

1 May 2014 in Neurosurgery
Verified
Journal Article
Closed access
PDF file
NCNohra Chalouhi
Nohra Chalouhi
MZMario Zanaty
Mario Zanaty
STStavropoula Tjoumakaris
Stavropoula Tjoumakaris
LGL. Fernando Gonzalez
L. Fernando Gonzalez
DHDavid Hasan
David Hasan
PJPascal Jabbour
Pascal Jabbour
BACKGROUND:. Endovascular vessel reconstruction with the pipeline embolization device (PED) has become common practice. Data on the safety and efficacy

18 February 2014 in Neuroradiology
Verified
Journal Article
Closed access
PDF file
MZMario Zanaty
Mario Zanaty
NCNohra Chalouhi
Nohra Chalouhi
STStavropoula I. Tjoumakaris
Stavropoula I. Tjoumakaris
LGL. Fernando Gonzalez
L. Fernando Gonzalez
RRRobert Rosenwasser
Robert Rosenwasser
PJPascal Jabbour
Pascal Jabbour

9 December 2013 in BioMed Research International
Verified
Journal Article
Open access
PDF file
MZMario Zanaty
Mario Zanaty
NCNohra Chalouhi
Nohra Chalouhi
RSRobert M. Starke
Robert M. Starke
STStavropoula Tjoumakaris
Stavropoula Tjoumakaris
LGL. Fernando Gonzalez
L. Fernando Gonzalez
PJPascal Jabbour
Pascal Jabbour
The management of mycotic aneurysm has always been subject to controversy. The aim of this paper is to review the literature on the intracranial infected aneurysm from pathogenesis till management while focusing mainly on the endovascular interventions. This novel solution seems to provide additional benefits and long-term favorable outcomes.

1 January 2014 in Frontiers in Neurology
Verified
Journal Article
Open access
PDF file
MZMario Zanaty
Mario Zanaty
NCNohra Chalouhi
Nohra Chalouhi
STStavropoula Tjoumakaris
Stavropoula Tjoumakaris
RRRobert H. Rosenwasser
Robert H. Rosenwasser
LGL. Fernando Gonzalez
L. Fernando Gonzalez
PJPascal Jabbour
Pascal Jabbour
Endovascular therapy is now the treatment of choice for intracranial aneurysms (IAs) for its efficacy and safety profile. The use of flow diversion (FD) has recently expanded to cover many types of IAs in various locations. Some institutions even attempt FD as first line treatment for unruptured IAs. The most widely used devices are the pipeline embolization device (PED), the SILK flow diverter (SFD), the flow redirection endoluminal device (FRED), and Surpass. Many questions were raised regarding the long-term complications, the optimal regimen of dual antiplatelet therapy, and the durability of treatment effect. We reviewed the literature to address these questions as well as other concerns on FD when treating IAs.

5 February 2014 in Neurological Research
Verified
Journal Article
Closed access
MZMario Zanaty
Mario Zanaty
NCNohra Chalouhi
Nohra Chalouhi
STStavropoula I. Tjoumakaris
Stavropoula I. Tjoumakaris
LGL. Fernando Gonzalez
L. Fernando Gonzalez
RRRobert H. Rosenwasser
Robert H. Rosenwasser
PJPascal M. Jabbour
Pascal M. Jabbour
The management of unruptured aneurysms (UAs), whose incidence is increasing, is still a controversial issue. Many studies have been investigating the link between the geometry of the aneurysm and the risk of future rupture in order to bring forth a clear decision plan. The different estimators studied are the aneurysm's geometry and hemodynamic features on one hand, and the patient's clinical characteristics on the other. We reviewed the literature while focusing on the different geometrical parameters that have been used in estimating the future risk of rupture. These include mainly the size ratio (SR), the aspect ratio, the non-sphericity index (NI), the undulation index (UI), and the vessel aneurysm inclination angle (AA), to name a few.