The current coronavirus disease 2019 (COVID-19) pandemic is one example of the scores of zoonotic diseases responsible for various outbreaks resulting in the deaths of millions of people for centuries. The COVID-19 pandemic has broken the age-old healthcare infrastructure and led to utter chaos. In the shadow of this pandemic, other zoonotic infections like the nipah virus, monkeypox, and langya virus, to name a few, have been neglected. Hence, outbreaks caused by such zoonotic viruses are rising in their endemic areas, like the Indian subcontinent. The mortality and morbidity due to such zoonoses are greater than usual due to the shortage of healthcare professionals caused by the COVID-19 crisis. Due to the lack of vaccines and therapeutics directed against this viral infection, treatment of patients is limited to supportive management and prevention, making preparedness for these potential zoonotic viral outbreaks essential. This paper highlights some of these zoonotic infections, which perpetuated and wreaked havoc while the world was occupied with containing the COVID-19 pandemic.

The Russian invasion of Ukraine in 2022 has caused a humanitarian crisis impacting millions of individuals within Ukraine and globally. While war-related healthcare delivery has been discussed in both the academic biomedical literature and in non-peer-reviewed sources, little academic attention has been paid to overseas medical students who have had to abandon their education. These constitute nearly a third of the 80,000 international students in Ukraine and represent a valuable part of the global healthcare workforce. This article utilizes the illustrative case of the over 18,000 Indian-origin medical students enrolled in Ukraine to review the state of overseas medical students in Ukraine and war-related interruption in education. Literature, both academic and non-academic, published up until October 1, 2022, pertaining to the conflict, the impact on students, the demands of various stakeholders, and the proposed solutions, was reviewed through the use of appropriate keyword-based searches. Factors influencing the decision to pursue education in Ukraine and their pre-crisis pathway to home practice are first discussed. Indian-origin students have historically gone on to Ukraine after securing insufficiently competitive ranks in the national medical school entrance exam, thus preventing them from getting a heavily subsidized education at publicly funded institutions in India. In the 2022 Russo-Ukrainian conflict, these students have faced not only actual and potential challenges related to their safety, shelter, food, and home return, they have been considerably impacted by the uncertainty regarding their educational prospects back home. The article then delineates the nuances and challenges in attempting to reintegrate a large potential healthcare workforce in the home country, and discusses possible solutions, especially those being implemented by the government. Urgent need exists for the involvement of all stakeholders and careful consensus-building before the proposed reintegration from an equity-based perspective.

Disease X is caused by pathogen X, an unknown infectious agent that can potentially trigger an epidemic or pandemic. Pathogen X might be any pathogen, including bacteria, viruses, parasites, fungi, and prions. WHO uses the term ‘Disease X’ for any new emerging disease caused by an unknown pathogen X. Disease X stands for any possible future pandemic in WHO’s shortlist of high-priority diseases. This review looks at the manifestations of the recent COVID-19 epidemic as the first Disease X to evaluate what has happened and to learn from what went wrong in India and worldwide. To this end, a summary is presented of response measures by governments, often lacking flows of information, discrepancies in the views of experts and decisions of policymakers, and undesirable variations in individual and collective behavior and their consequences. The elements of combating Disease X in a world with considerable inequalities in relevant knowledge, expertise, information, quality of governance, and financial possibilities are discussed. Based on this, recommendations are given for an innovative global pandemic preparedness system.