Introduction: Wular Lake, one of the largest freshwater lakes in South Asia and a Ramsar-designated site, sustains biodiversity, fisheries, and livelihoods in the Kashmir Valley. However, increasing anthropogenic activities have raised concerns about heavy metal (HM) contamination in its sediments due to their persistence and ecological risks.Methods: A total of 32 surface sediment samples were collected from Wular Lake to determine the levels, distribution, and potential sources of HMs including Co, Cu, Fe, Mn, Ni, Pb, Zn, and Cr. Grain size composition, concentration analysis, and pollution indices such as contamination factor (CF), geoaccumulation index (Igeo), enrichment factor (EF), pollution load index (PLI), and potential ecological risk index (PERI) were applied. Multivariate statistics, including correlation, factor, and cluster analyses, were used to identify pollution sources.Results: Sediments predominantly comprised silt (5.8%–88.8%). Average HM concentrations were Co (34.26 mg/kg), Cu (53.2 mg/kg), Mn (1,478 mg/kg), Ni (78.85 mg/kg), Zn (113 mg/kg), and Cr (96.08 mg/kg), all exceeding natural background levels, suggesting anthropogenic enrichment. Risk assessment indicated moderate contamination (PLI = 1.17; PERI = 19.20), with site-specific hotspots of elevated pollution. Strong correlations were observed among Co, Ni, Fe and among Cu, Pb, Zn. Factor analysis attributed 77.1% of the variance to industrial, urban, and agricultural activities, while cluster analysis segregated sites according to pollution intensity.Discussion: The findings indicate that Wular Lake sediments are moderately contaminated by heavy metals, primarily due to industrial discharge, agricultural practices, and urban runoff. Although the overall ecological risk was low to moderate, localized hotspots warrant urgent monitoring and management. Strengthening pollution mitigation measures is essential to safeguard the ecological health of this Ramsar site.

This study investigates the antioxidant and antimicrobial potential of Arisaema propinquum, a medicinal herb from the Pir Panjal range of the Kashmir Himalayas. Caffeic acid was isolated and characterized from methanolic extracts of its aerial parts. Fourier-transform infrared (FTIR) spectroscopy confirmed the presence of functional groups indicative of polyphenols, flavonoids, terpenoids, esters, and other metabolites. In vitro antioxidant activity was assessed using the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging, superoxide dismutase (SOD) mimetic, and deoxyribose degradation assays. The deoxyribose assay showed dose-dependent inhibition of 63.2%, 69.7%, and 80.3% at concentrations of 100, 150, and 200 µg/mL, respectively, while the methanolic extract exhibited an IC₅₀ of 49.74 µg/mL in the H₂O₂ scavenging assay. Total phenolic and flavonoid contents were quantified as 40.33 ± 1.9 mg GAE/g DW and 32.77 ± 1.35 mg rutin equivalent/g DW, respectively. In vivo antioxidant activity was evaluated using Saccharomyces cerevisiae, where the extract supported 76.17 ± 0.58% cell survival under oxidative stress. The findings suggest that the antioxidant and antimicrobial properties of A. propinquum are attributable to its rich phytochemical profile, supporting its potential in therapeutic applications.