Praveen Kumar Dikkala

Dr. Praveen Kumar Dikkala


Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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11 January 2022 in Foods
Verified
Journal Article
Open access
PDF file
Minaxi SharmaMinaxi Sharma
Minaxi Sharma
Stephen Inbaraj BaskaranStephen Inbaraj Baskaran
Stephen Inbaraj Baskaran
PDPraveen Kumar Dikkala
Praveen Kumar Dikkala
KSKandi Sridhar
Kandi Sridhar
AMArjun Naik Mude
Arjun Naik Mude
KNKairam Narsaiah
Kairam Narsaiah
Curcumin has been demonstrated to have biological activities and its fortification in food products is an important strategy to deliver bioactive ingredients at target sites. However, studies have documented a curcumin low bioavailability and low intake. Hence, combining functional ingredients with food should be needed to prevent widespread nutrient intake shortfalls and associated deficiencies. Thus, curcumin was encapsulated in calcium-alginate and their characteristics as well as in vitro release behavior of curcumin hydrogel beads (CHBs) was studied. Moreover, CHBs were fortified in development of functional Kulfi and their quality characteristics were studied. The encapsulation efficiency was up to 95.04%, indicating that most of the curcumin was entrapped. FTIR shifts in the bands were due to the replacement of sodium ions to the calcium ions. In vitro release (%) for CHBs was found to be 67.15% after 2 h, which increased slightly up to 67.88% after 4 h. The average swelling index of CHBs was found to be 10.21 to 37.92 from 2 to 12 h in PBS (pH 7.40). Control and Kulfi fortified with CHBs showed no significant difference (p > 0.05) in colour (L = 73.03 and 75.88) and the melting rate (0.88 mL/min and 0.63 mL/min), respectively. Standard plate count was reduced in the Kulfi fortified with CHBs (13.77 × 104 CFU/mL) with high sensory score for overall acceptability (8.56) compared to the control (154.70 × 104 CFU/mL). These findings suggested the feasibility of developing CHBs to mask the bitterness, enhance the solubility, and increase the bioavailability in gastrointestinal conditions. Additionally, Kulfi could be a suitable dairy delivery system for curcumin bioactive compounds.

8 August 2023 in Foods
Verified
Journal Article
Open access
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Deepanka SaikiaDeepanka Saikia
Deepanka Saikia
RKRadhakrishnan Kesavan
Radhakrishnan Kesavan
Stephen Inbaraj BaskaranStephen Inbaraj Baskaran
Stephen Inbaraj Baskaran
PDPraveen Kumar Dikkala
Praveen Kumar Dikkala
Prakash Kumar NayakPrakash Kumar Nayak
Prakash Kumar Nayak
KSKandi Sridhar
Kandi Sridhar
Elephant apple (Dillenia indica L.) grows wild in Southeast Asia’s forests, including in China, India, Nepal, Bangladesh, and Sri Lanka. Elephant apples are considered essential fruit crops because of their high nutritional value, which includes high levels of vitamin C, carbohydrates, fats, fibre, protein, minerals, and fatty acids. It is important to understand the nutritional value and health benefits of elephant apples in order to increase fruit intake in people’s daily diets. The present review paper focuses on elephant apple’s phytochemistry, bioactive compounds, therapeutic value, and medicinal capabilities for designing and developing a wide range of food formulations. Proteins, minerals, fats, crude fibre, carbohydrates, vitamin C, tannins, malic acid, and glucose are abundant in the leaves, bark, and fruit of the elephant apple. In addition to nutritional components, many phytochemicals found in elephant apples have been identified as bioactive compounds with a broad range of biological activities, the most prominent of which are antioxidant, anticancer, antidiabetic, and anti-inflammatory properties. Overall, elephant apple is a rich, natural source of bioactive compounds with potential applications in the production of value-added foods and nutraceuticals for disease prevention and management.

7 January 2025 in Pharmaceutics
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Journal Article
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RPRachitha P
Rachitha P
Nagaraj BasavegowdaNagaraj Basavegowda
Nagaraj Basavegowda
NLNityashree Kyathegowdanadoddi Lakshmanagowda
Nityashree Kyathegowdanadoddi Lakshmanagowda
VRVinay Raghavendra
Vinay Raghavendra
Niju sagar.DNiju sagar.D
Niju sagar.D
Minaxi SharmaMinaxi Sharma
Minaxi Sharma
Malignant growth is expected to surpass other significant causes of death as one of the top reasons for dismalness and mortality worldwide. According to a World Health Organization (WHO) study, this illness causes approximately between 9 and 10 million instances of deaths annually. Chemotherapy, radiation, and surgery are the three main methods of treating cancer. These methods seek to completely eradicate all cancer cells while having the fewest possible unintended impacts on healthy cell types. Owing to the lack of target selectivity, the majority of medications have substantial side effects. On the other hand, nanomaterials have transformed the identification, diagnosis, and management of cancer. Nanostructures with biomimetic properties have been grown as of late, fully intent on observing and treating the sickness. These nanostructures are expected to be consumed by growth in areas with profound disease. Furthermore, because of their extraordinary physicochemical properties, which incorporate nanoscale aspects, a more prominent surface region, explicit geometrical features, and the ability to embody different substances within or on their outside surfaces, nanostructures are remarkable nano-vehicles for conveying restorative specialists to their designated regions. This review discusses recent developments in nanostructured materials such as graphene, dendrimers, cell-penetrating peptide nanoparticles, nanoliposomes, lipid nanoparticles, magnetic nanoparticles, and nano-omics in the diagnosis and management of cancer.

22 January 2022 in Agriculture
Verified
Journal Article
Open access
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PRPreethi Rokalla
Preethi Rokalla
Stephen Inbaraj BaskaranStephen Inbaraj Baskaran
Stephen Inbaraj Baskaran
PDPraveen Kumar Dikkala
Praveen Kumar Dikkala
KSKandi Sridhar
Kandi Sridhar
DDDaniel Smith Dasi
Daniel Smith Dasi
NKNaveen Kumar Kalletlapally
Naveen Kumar Kalletlapally
Modified atmosphere packaging (MAP) has been widely applied to extend the shelf-life of fresh-cut produces, such as ready-to-eat pomegranate arils. However, many studies used MAP to extend the shelf-life of arils at 3, 4, and 15 °C. The evidence suggested that MAP can extend the shelf-life of arils at an ambient temperature. Therefore, we attempted to extend the shelf-life of ready-to-eat pomegranate arils using active MAP at an ambient temperature and evaluated its chemical, quality, and microbial properties. Samples were flushed with specific gas compositions of oxygen (O2) and carbon dioxide (CO2) at an ambient temperature and 60 ± 2% relative humidity (RH). The findings demonstrated that active MAP increased the titratable acidity (0.32–3.64%), anthocyanins (0.27–0.42 g/L), reducing sugars (1.06–10.13%), and total soluble solids (15–19 °Brix), while it decreased the pH (3.20–3.54) and hardness (4.60–9.40 N) with a microbial load of ≤5 log CFU/g at ambient temperature for 5 days. Ultimately, active MAP could be an effective technique to be used in ready-to-eat produce industries and has the potential to guarantee a longer shelf-life at ambient temperature without the use of refrigerator facilities.

22 April 2024 in Foods
Verified
Journal Article
Open access
PDF file
RJRifat Jabeen
Rifat Jabeen
NJNusrat Jan
Nusrat Jan
BNBazila Naseer
Bazila Naseer
Prakash Kumar SarangiPrakash Kumar Sarangi
Prakash Kumar Sarangi
KSKandi Sridhar
Kandi Sridhar
Stephen Inbaraj BaskaranStephen Inbaraj Baskaran
Stephen Inbaraj Baskaran
γ-aminobutyric acid (GABA), recognized as a primary inhibitory neurotransmitter within the brain, serves a crucial role in the aging process and in neurodegenerative conditions such as Alzheimer’s disease. Research has demonstrated the beneficial effects of GABA, particularly for elderly individuals. Given that elderly individuals often encounter challenges with swallowing food, beverages designed to address dysphagia represent a preferable option for this demographic. Among the different processing techniques, the germination process triggers biochemical changes, leading to an increase in certain nutrients and bioactive compounds (e.g., GABA). Therefore, we attempted to develop a novel functional beverage utilizing germinated brown rice enriched with GABA and studied its nutritional and bio-functional characterization. The optimal conditions (X1, X2, X3 and X4.) were determined: powdered sugar (40 g), chocolate powder (20 g), sodium carboxymethyl cellulose (0.5 g), GBR (220 g), and water (440 mL). The results of storage studies indicated that the germinated-brown-rice-based beverage exhibited favorable nutritional attributes, including increased γ-oryzanol (52.73 ± 1.56%), total phenolic content (26.68 ± 1.56 mg GAE/100 g), niacin (5.17 ± 0.14%), and GABA (42.12 ± 0.63 mg/100 g) levels. Additionally, the beverage demonstrated notable antioxidant activity (74.23 ± 2.37 µmol TE/100 g), suggesting potential health-promoting effects. Sensory evaluation revealed satisfactory acceptability among consumers, highlighting its palatability. Overall, this study elucidates the development of a novel functional beverage utilizing germinated brown rice enriched with GABA, offering promising nutritional and bio-functional characteristics for health-conscious consumers.

25 October 2021 in Journal of Food Processing and Preservation
Verified
Journal Article
Closed access
PDF file
SVSai Krishna Vedantam
Sai Krishna Vedantam
JSJhansi Lakshmi Sagili
Jhansi Lakshmi Sagili
PDPraveen Kumar Dikkala
Praveen Kumar Dikkala
KSKandi Sridhar
Kandi Sridhar
Celiac disease is triggered by consumption of gluten-rich foods that has emerged as a major global health problem. In fact, it is now important to look for an alternate and cheap source to develop gluten-free diet using alternative ingredients. Therefore, the aim of the study was to evaluate the effect of moth bean flour and xanthan gum addition on the functional, thermal, pasting, and rheological properties of gluten-free maize dough. The results showed that the addition of moth bean and xanthan gum increased the functional (e.g., water absorption capacity of 1.89-2.52 g/g) and thermal (e.g., gelatinization onset temperature (To: 68.55-70.55 °C) and enthalpy (ΔH: 1.66-2.89 J/g)) properties, while pasting properties varied. All formulations showed more solid-elastic than viscous behaviour (G'>G") with tan δ <1. Thus, the study concluded that the addition of protein source and hydrocolloid to maize flour can be a potential alternative to develop gluten-free bread and buns.