Producing and manipulating graphene on fab-compatible scale, while maintaining its remarkable carrier mobility, is key to finalize its technological application. We show that a large-scale approach (chemical vapor deposition on Cu followed by polymer-mediated semi-dry transfer) yields single-layer graphene crystals fully comparable, in terms of electronic transport, to micro-mechanically exfoliated flakes. Hexagonal boron nitride is used to encapsulate the graphene crystals—without taking part to their detachment from the growth catalyst—and study their intrinsic properties in field-effect devices. At room temperature, the electron-phonon coupling sets the mobility to ∼ 1.3 × 10⁵ cm² V⁻¹ s⁻¹ at ∼ 10¹¹ cm⁻² concentration. At T = 4.2 K, the mobility (>6 × 10⁵ cm² V⁻¹ s⁻¹ at ∼ 10¹¹ cm⁻²) is limited by the devices’ physical edges, and charge fluctuations < 7 × 10⁹ cm⁻² are detected. Under perpendicular magnetic fields, we observe early onset of Landau quantization (B ∼ 50 mT) and signatures of electronic correlation, including the fractional quantum Hall effect.